公开(公告)号：US09393433B2

公开(公告)日：2016-07-19

申请号：US13489770

申请日：2012-06-06

申请人： Jordi Parramon ,  Goran N. Marnfeldt ,  Robert Ozawa ,  Emanuel Feldman ,  Dave Peterson

发明人： Jordi Parramon ,  Goran N. Marnfeldt ,  Robert Ozawa ,  Emanuel Feldman ,  Dave Peterson ,  Yuping He

IPC分类号： A61N1/378 ,  A61N1/08

CPC分类号： A61N1/3787 ,  A61N1/08

摘要： Battery management circuitry for an implantable medical device such as an implantable neurostimulator is described. The circuitry has a T-shape with respect to the battery terminal, with charging circuitry coupled between rectifier circuitry and the battery terminal on one side of the T, and load isolation circuitry coupled between the load and the battery terminal on the other side. The load isolation circuitry can comprise two switches wired in parallel. An undervoltage fault condition opens both switches to isolate the battery terminal from the load to prevent further dissipation of the battery. Other fault conditions will open only one the switches leaving the other closed to allow for reduced power to the load to continue implant operations albeit at safer low-power levels. The battery management circuitry can be fixed in a particular location on an integrated circuit which also includes for example the stimulation circuitry for the electrodes.

摘要翻译： 描述了诸如可植入神经刺激器的可植入医疗装置的电池管理电路。 电路相对于电池端子具有T形，充电电路耦合在整流器电路和T的一侧上的电池端子之间，负载隔离电路耦合在另一侧的负载和电池端子之间。 负载隔离电路可以包括并联的两个开关。 欠压故障条件打开两个开关以将电池端子与负载隔离，以防止电池进一步耗散。 其他故障条件将仅打开一个开关，使另一个闭合，以允许降低负载的功率，以继续进行种植体操作，尽管处于更安全的低功率水平。 电池管理电路可以固定在集成电路的特定位置，该集成电路还包括例如用于电极的刺激电路。

公开(公告)号：US20130023943A1

公开(公告)日：2013-01-24

申请号：US13489770

申请日：2012-06-06

申请人： Jordi Parramon ,  Goran N. Marnfeldt ,  Robert Ozawa ,  Emanuel Feldman ,  Dave Peterson

发明人： Jordi Parramon ,  Goran N. Marnfeldt ,  Robert Ozawa ,  Emanuel Feldman ,  Dave Peterson ,  Yuping He

IPC分类号： A61N1/36

CPC分类号： A61N1/3787 ,  A61N1/08

摘要： Battery management circuitry for an implantable medical device such as an implantable neurostimulator is described. The circuitry has a T-shape with respect to the battery terminal, with charging circuitry coupled between rectifier circuitry and the battery terminal on one side of the T, and load isolation circuitry coupled between the load and the battery terminal on the other side. The load isolation circuitry can comprise two switches wired in parallel. An undervoltage fault condition opens both switches to isolate the battery terminal from the load to prevent further dissipation of the battery. Other fault conditions will open only one the switches leaving the other closed to allow for reduced power to the load to continue implant operations albeit at safer low-power levels. The battery management circuitry can be fixed in a particular location on an integrated circuit which also includes for example the stimulation circuitry for the electrodes.

摘要翻译： 描述了诸如可植入神经刺激器的可植入医疗装置的电池管理电路。 电路相对于电池端子具有T形，充电电路耦合在整流器电路和T的一侧上的电池端子之间，负载隔离电路耦合在另一侧的负载和电池端子之间。 负载隔离电路可以包括并联的两个开关。 欠压故障条件打开两个开关以将电池端子与负载隔离，以防止电池进一步耗散。 其他故障条件将仅打开一个开关，使另一个闭合，以允许降低负载的功率，以继续进行种植体操作，尽管处于更安全的低功率水平。 电池管理电路可以固定在集成电路的特定位置，该集成电路还包括例如用于电极的刺激电路。

公开(公告)号：US20110015705A1

公开(公告)日：2011-01-20

申请号：US12883797

申请日：2010-09-16

申请人： Paul J. Griffith ,  Jordi Parramon ,  Goran N. Marnfeldt ,  Daniel Aghassisn ,  Kiran Nimmagadda ,  Emanuel Feldman ,  Jess W. Shi

发明人： Paul J. Griffith ,  Jordi Parramon ,  Goran N. Marnfeldt ,  Daniel Aghassisn ,  Kiran Nimmagadda ,  Emanuel Feldman ,  Jess W. Shi

IPC分类号： A61N1/08

CPC分类号： A61N1/36125 ,  A61N1/025 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/36071

摘要： An improved architecture for an implantable medical device such as an implantable pulse generator (IPG) is disclosed. In one embodiment, the various functional blocks for the IPG are incorporated into a signal integrated circuit (IC). Each of the functional blocks communicate with each other, and with other off-chip devices if necessary, via a centralized bus governed by a communication protocol. To communicate with the bus and to adhere to the protocol, each circuit block includes bus interface circuitry adherent with that protocol. Because each block complies with the protocol, any given block can easily be modified or upgraded without affecting the design of the other blocks, facilitating debugging and upgrading of the IPG circuitry. Moreover, because the centralized bus can be taken off the integrated circuit, extra circuitry can easily be added off chip to modify or add functionality to the IPG without the need for a major redesign of the main IPG IC.

摘要翻译： 公开了一种用于植入式医疗装置（例如植入式脉冲发生器（IPG））的改进的架构。 在一个实施例中，用于IPG的各种功能块被并入到信号集成电路（IC）中。 每个功能块通过由通信协议管理的集中式总线彼此通信，并且如果需要，与其他片外设备通信。 为了与总线进行通信并遵守协议，每个电路块包括与该协议相关的总线接口电路。 由于每个块符合协议，任何给定的块都可以轻松修改或升级，而不影响其他块的设计，便于IPG电路的调试和升级。 此外，由于集中式总线可以从集成电路中取出，所以额外的电路可以轻松地从芯片上添加到IPG中，以便对IPG进行主要的重新设计。

公开(公告)号：US20080319497A1

公开(公告)日：2008-12-25

申请号：US11767636

申请日：2007-06-25

申请人： Paul J. Griffith ,  Jordi Parramon ,  Goran N. Marnfeldt ,  Daniel Aghassian ,  Kiran Nimmagadda ,  Emanuel Feldman ,  Jess W. Shi

发明人： Paul J. Griffith ,  Jordi Parramon ,  Goran N. Marnfeldt ,  Daniel Aghassian ,  Kiran Nimmagadda ,  Emanuel Feldman ,  Jess W. Shi

IPC分类号： A61N1/08

CPC分类号： A61N1/36125 ,  A61N1/025 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/36071

摘要： An improved architecture for an implantable medical device such as an implantable pulse generator (IPG) is disclosed. In one embodiment, the various functional blocks for the IPG are incorporated into a signal integrated circuit (IC). Each of the functional blocks communicate with each other, and with other off-chip devices if necessary, via a centralized bus governed by a communication protocol. To communicate with the bus and to adhere to the protocol, each circuit block includes bus interface circuitry adherent with that protocol. Because each block complies with the protocol, any given block can easily be modified or upgraded without affecting the design of the other blocks, facilitating debugging and upgrading of the IPG circuitry. Moreover, because the centralized bus can be taken off the integrated circuit, extra circuitry can easily be added off chip to modify or add functionality to the IPG without the need for a major redesign of the main IPG IC.

摘要翻译： 公开了一种用于植入式医疗装置（例如植入式脉冲发生器（IPG））的改进的架构。 在一个实施例中，用于IPG的各种功能块被并入到信号集成电路（IC）中。 每个功能块通过由通信协议管理的集中式总线彼此通信，并且如果需要，与其他片外设备通信。 为了与总线进行通信并遵守协议，每个电路块包括与该协议相关的总线接口电路。 由于每个块符合协议，任何给定的块都可以轻松修改或升级，而不影响其他块的设计，便于IPG电路的调试和升级。 此外，由于集中式总线可以从集成电路中取出，所以额外的电路可以轻松地从芯片上添加到IPG中，以便对IPG进行主要的重新设计。

公开(公告)号：US08649858B2

公开(公告)日：2014-02-11

申请号：US11767636

申请日：2007-06-25

申请人： Paul J. Griffith ,  Jordi Parramon ,  Goran N. Marnfeldt ,  Daniel Aghassian ,  Kiran Nimmagadda ,  Emanuel Feldman ,  Jess W. Shi

发明人： Paul J. Griffith ,  Jordi Parramon ,  Goran N. Marnfeldt ,  Daniel Aghassian ,  Kiran Nimmagadda ,  Emanuel Feldman ,  Jess W. Shi

IPC分类号： A61N1/36 ,  A61N1/08

CPC分类号： A61N1/36125 ,  A61N1/025 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/36071

摘要： An improved architecture for an implantable medical device such as an implantable pulse generator (IPG) is disclosed. In one embodiment, the various functional blocks for the IPG are incorporated into a signal integrated circuit (IC). Each of the functional blocks communicate with each other, and with other off-chip devices if necessary, via a centralized bus governed by a communication protocol. To communicate with the bus and to adhere to the protocol, each circuit block includes bus interface circuitry adherent with that protocol. Because each block complies with the protocol, any given block can easily be modified or upgraded without affecting the design of the other blocks, facilitating debugging and upgrading of the IPG circuitry. Moreover, because the centralized bus can be taken off the integrated circuit, extra circuitry can easily be added off chip to modify or add functionality to the IPG without the need for a major redesign of the main IPG IC.

摘要翻译： 公开了一种用于植入式医疗装置（例如植入式脉冲发生器（IPG））的改进的架构。 在一个实施例中，用于IPG的各种功能块被并入到信号集成电路（IC）中。 每个功能块通过由通信协议管理的集中式总线彼此通信，并且如果需要，与其他片外设备通信。 为了与总线进行通信并遵守协议，每个电路块包括与该协议相关的总线接口电路。 由于每个块符合协议，任何给定的块都可以轻松修改或升级，而不影响其他块的设计，便于IPG电路的调试和升级。 此外，由于集中式总线可以从集成电路中取出，所以额外的电路可以轻松地从芯片上添加到IPG中，以便对IPG进行主要的重新设计。

公开(公告)号：US08666504B2

公开(公告)日：2014-03-04

申请号：US13608490

申请日：2012-09-10

申请人： Vasily Dronov ,  Jordi Parramon ,  Robert Ozawa ,  Md. Mizanur Rahman ,  Emanuel Feldman

发明人： Vasily Dronov ,  Jordi Parramon ,  Robert Ozawa ,  Md. Mizanur Rahman ,  Emanuel Feldman

IPC分类号： A61N1/05

CPC分类号： H01F38/14 ,  A61N1/36 ,  A61N1/37223 ,  A61N1/3787 ,  H02J50/12 ,  H04Q9/12

摘要： Communication and charging circuitry for an implantable medical device is described having a single coil for receiving charging energy and for data telemetry. The circuitry removes from the AC side of the circuit a tuning capacitor and switch traditionally used to tune the tank circuitry to different frequencies for telemetry and charging. As such, the tank circuitry is simplified and contains no switchable components. A switch is serially connected to the storage capacitor on the DC side of the circuit. During telemetry, the switch is opened, thus disconnecting the storage capacitor from the tank circuit, and alleviating concerns that this capacitor will couple to the tank circuit and interfere with telemetry operations. During charging, the switch is closed, which allows the storage capacitor to couple to the tank circuitry through the rectifier during some portions of the tank circuitry's resonance.

摘要翻译： 描述了用于可植入医疗装置的通信和充电电路，其具有用于接收充电能量和用于数据遥测的单个线圈。 该电路从电路的AC侧消除了调谐电容器和传统上用于将电路调谐到不同频率的开关，用于遥测和充电。 因此，容器电路被简化并且不包含可切换的部件。 开关串联连接到电路直流侧的存储电容器。 在遥测期间，开关打开，从而将存储电容器与储能电路断开，并减轻该电容器将耦合到储能电路并干扰遥测操作的担忧。 在充电期间，开关闭合，这允许存储电容器在储罐电路的共振的某些部分期间通过整流器耦合到储能电路。

公开(公告)号：US20130103115A1

公开(公告)日：2013-04-25

申请号：US13608490

申请日：2012-09-10

申请人： Vasily Dronov ,  Jordi Parramon ,  Robert Ozawa ,  Md. Mizanur Rahman ,  Emanuel Feldman

发明人： Vasily Dronov ,  Jordi Parramon ,  Robert Ozawa ,  Md. Mizanur Rahman ,  Emanuel Feldman

IPC分类号： A61N1/08

CPC分类号： H01F38/14 ,  A61N1/36 ,  A61N1/37223 ,  A61N1/3787 ,  H02J50/12 ,  H04Q9/12

摘要： Communication and charging circuitry for an implantable medical device is described having a single coil for receiving charging energy and for data telemetry. The circuitry removes from the AC side of the circuit a tuning capacitor and switch traditionally used to tune the tank circuitry to different frequencies for telemetry and charging. As such, the tank circuitry is simplified and contains no switchable components. A switch is serially connected to the storage capacitor on the DC side of the circuit. During telemetry, the switch is opened, thus disconnecting the storage capacitor from the tank circuit, and alleviating concerns that this capacitor will couple to the tank circuit and interfere with telemetry operations. During charging, the switch is closed, which allows the storage capacitor to couple to the tank circuitry through the rectifier during some portions of the tank circuitry's resonance.

摘要翻译： 描述了用于可植入医疗装置的通信和充电电路，其具有用于接收充电能量和用于数据遥测的单个线圈。 该电路从电路的AC侧消除了调谐电容器和传统上用于将电路调谐到不同频率的开关，用于遥测和充电。 因此，容器电路被简化并且不包含可切换的部件。 开关串联连接到电路直流侧的存储电容器。 在遥测期间，开关打开，从而将存储电容器与储能电路断开，并减轻该电容器将耦合到储能电路并干扰遥测操作的担忧。 在充电期间，开关闭合，这允许存储电容器在储罐电路的共振的某些部分期间通过整流器耦合到储能电路。

公开(公告)号：US07881803B2

公开(公告)日：2011-02-01

申请号：US11550655

申请日：2006-10-18

申请人： Jordi Parramon ,  Kiran Nimmagadda ,  Emanuel Feldman ,  Yuping He

发明人： Jordi Parramon ,  Kiran Nimmagadda ,  Emanuel Feldman ,  Yuping He

IPC分类号： A61N1/40

CPC分类号： A61N1/36125 ,  A61N1/025 ,  A61N1/08 ,  A61N1/372 ,  A61N1/37205 ,  A61N1/3756

摘要： Disclosed herein are circuits and methods for a multi-electrode implantable stimulator device incorporating one decoupling capacitor in the current path established via at least one cathode electrode and at least one anode electrode. In one embodiment, the decoupling capacitor may be hard-wired to a dedicated anode on the device. The cathodes are selectively activatable via stimulation switches. In another embodiment, any of the electrodes on the devices can be selectively activatable as an anode or cathode. In this embodiment, the decoupling capacitor is placed into the current path via selectable anode and cathode stimulation switches. Regardless of the implementation, the techniques allow for the benefits of capacitive decoupling without the need to associate decoupling capacitors with every electrode on the multi-electrode device, which saves space in the body of the device. Although of particular benefit when applied to microstimulators, the disclosed technique can be used with space-saving benefits in any stimulator device.

摘要翻译： 本文公开了用于在经由至少一个阴极电极和至少一个阳极电极建立的电流路径中并入一个去耦电容器的多电极可植入刺激器装置的电路和方法。 在一个实施例中，去耦电容器可以硬连接到器件上的专用阳极。 阴极可以通过刺激开关选择性地激活。 在另一个实施例中，器件上的任何电极可以选择性地激活为阳极或阴极。 在该实施例中，去耦电容通过可选择的阳极和阴极刺激开关放置在电流路径中。 不管实施方案如何，这些技术允许电容去耦的优点，而不需要将去耦电容器与多电极器件上的每个电极相关联，这节省了器件体内的空间。 虽然在应用于微型激励器时特别有益，但是所公开的技术可以在任何刺激器装置中具有节省空间的优点。

公开(公告)号：US08768453B2

公开(公告)日：2014-07-01

申请号：US13237531

申请日：2011-09-20

申请人： Jordi Parramon ,  Jess W. Shi ,  Emanuel Feldman

发明人： Jordi Parramon ,  Jess W. Shi ,  Emanuel Feldman

IPC分类号： A61N1/08

CPC分类号： A61N1/37241 ,  A61N1/025 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/08 ,  A61N1/3605 ,  A61N1/36125 ,  A61N1/36153

摘要： Electrode voltage monitoring circuitry for an implantable neurostimulator system having a plurality of electrode-driver integrated circuits (ICs) in provided. Electrodes from either or both ICs can be chosen to provide stimulation, and one of the IC acts as the master while the other acts as the slave. Electrodes voltages on the slave IC are routed to the master IC, and thus the master IC can monitor both electrode voltages on the slave as well as electrode voltages on the master. Such voltages can be monitored for a variety of purposes, and in particular use of such voltage is disclosed for determining the resistance between electrodes and to set a compliance voltage for stimulation.

摘要翻译： 一种具有多个电极驱动器集成电路（IC）的可植入神经刺激器系统的电极电压监视电路。 可以选择来自任一个或两个IC的电极以提供刺激，并且IC中的一个用作主器件，而另一个用作从器件。 从IC上的电极电压被路由到主IC，因此主IC可以监控从站上的两个电极电压以及主站上的电极电压。 为了各种目的可以监测这样的电压，并且特别地使用这种电压来确定电极之间的电阻并设置用于刺激的顺应性电压。

公开(公告)号：US20070055308A1

公开(公告)日：2007-03-08

申请号：US11221095

申请日：2005-09-06

申请人： Matthew Haller ,  Jordi Parramon ,  Emanuel Feldman

发明人： Matthew Haller ,  Jordi Parramon ,  Emanuel Feldman

IPC分类号： A61N1/00

CPC分类号： A61N1/3787 ,  A61N1/37247 ,  A61N1/37258 ,  A61N1/37264

摘要： A stimulator includes an implantable pulse generator comprising circuit elements, a first power source, such as an ultracapacitor, that provides operating power for the circuit elements of the pulse generator. The pulse generator can also have a memory associated therewith, such as a volatile memory for storing programming data. A second power source that has higher voltage retention than the first power source can also be included. The second power source can be dedicated to the volatile memory and can provide operating power for the volatile memory.

摘要翻译： 刺激器包括可植入脉冲发生器，其包括电路元件，第一电源，例如超级电容器，其为脉冲发生器的电路元件提供工作电力。 脉冲发生器还可以具有与其相关联的存储器，诸如用于存储编程数据的易失性存储器。 还可以包括比第一电源具有更高的电压保持的第二电源。 第二个电源可以专用于易失性存储器，并且可以为易失性存储器提供工作电源。