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公开(公告)号：US07137974B2
公开(公告)日：2006-11-21
申请号：US10626282
申请日：2003-07-24
申请人： Joseph M. Almasian , Brett M. Belongia , Frank Lentine , Martin Morrissey , Curtis Nauseda , Chau Nguyen , Stephen Proulx , Naren Renganath
发明人： Joseph M. Almasian , Brett M. Belongia , Frank Lentine , Martin Morrissey , Curtis Nauseda , Chau Nguyen , Stephen Proulx , Naren Renganath
CPC分类号： F16L29/007 , A61M39/14 , A61M39/18 , A61M39/22 , F16L2201/44 , G01N1/2035 , G01N2001/205 , G01N2001/2071 , Y10S604/905 , Y10T137/87925
摘要： A sterile to sterile connection device comprising a connector and one or more coupling devices. The connector has body portion which has two openings sealed from the environment so as to form a sterile environment within the connector. At least one of the openings being sealed from the environment by a sterile barrier plug. The connector also has a port capable movement within the body of the connector to at least an open and a closed position. The coupling device is formed of a body having two openings and a stem having a bore through at least a portion of the stem. The stem is contained within the body and capable of moving at least linearly through the body between a first and second stem position. One of the openings of the stem is sealed from the environment by a sterile barrier plug and the other is sealed to a presterilized component. The coupling device opening containing the sterile barrier plug is attached to either the inlet or outlet of the connector.
摘要翻译： 一种无菌至无菌连接装置，包括连接器和一个或多个联接装置。 连接器具有主体部分，其具有与环境密封的两个开口，以便在连接器内形成无菌环境。 至少一个开口通过无菌隔离塞与环境密封。 连接器还具有能够在连接器主体内移动至少至少一个打开和关闭位置的端口。 联接装置由具有两个开口的主体和具有穿过杆的至少一部分的孔的杆构成。 杆体容纳在主体内并且能够至少在第一和第二杆位置之间线性移动通过主体。 杆的一个开口通过无菌阻塞塞与环境密封，另一个被密封到预先灭活的部件上。 包含无菌阻塞塞的联接装置开口连接到连接器的入口或出口。
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公开(公告)号：US20050090797A1
公开(公告)日：2005-04-28
申请号：US10626282
申请日：2003-07-24
申请人： Joseph Almasian , Brett Belongia , Frank Lentine , Martin Morrissey , Curtis Nauseda , Chau Nguyen , Stephen Proulx , Naren Renganath
发明人： Joseph Almasian , Brett Belongia , Frank Lentine , Martin Morrissey , Curtis Nauseda , Chau Nguyen , Stephen Proulx , Naren Renganath
CPC分类号： F16L29/007 , A61M39/14 , A61M39/18 , A61M39/22 , F16L2201/44 , G01N1/2035 , G01N2001/205 , G01N2001/2071 , Y10S604/905 , Y10T137/87925
摘要： A sterile to sterile connection device comprising a connector and one or more coupling devices. The connector has body portion which has two openings sealed from the environment so as to form a sterile environment within the connector. At least one of the openings being sealed from the environment by a sterile barrier plug. The connector also has a port capable movement within the body of the connector to at least an open and a closed position. The coupling device is formed of a body having two openings and a stem having a bore through at least a portion of the stem. The stem is contained within the body and capable of moving at least linearly through the body between a first and second stem position. One of the openings of the stem is sealed from the environment by a sterile barrier plug and the other is sealed to a presterilized component. The coupling device opening containing the sterile barrier plug is attached to either the inlet or outlet of the connector.
摘要翻译： 一种无菌至无菌连接装置，包括连接器和一个或多个联接装置。 连接器具有主体部分，其具有与环境密封的两个开口，以便在连接器内形成无菌环境。 至少一个开口通过无菌隔离塞与环境密封。 连接器还具有能够在连接器主体内移动至少至少一个打开和关闭位置的端口。 联接装置由具有两个开口的主体和具有穿过杆的至少一部分的孔的杆构成。 杆体容纳在主体内并且能够至少在第一和第二杆位置之间线性移动通过主体。 杆的一个开口通过无菌阻塞塞与环境密封，另一个被密封到预先灭活的部件上。 包含无菌阻塞塞的联接装置开口连接到连接器的入口或出口。
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公开(公告)号：US20070106264A1
公开(公告)日：2007-05-10
申请号：US11584301
申请日：2006-10-20
CPC分类号： F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要： The present invention relates to a process for the sterile transfer of fluids, be they liquids or gases. It uses a presterilized device comprised of a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to a downstream component such as a filter, pipeline, sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components. The device is attached to an upstream component and the face and the first end of the plunger are steam sterilized in place.
摘要翻译： 本发明涉及一种无菌转移流体（无论是液体还是气体）的方法。 它使用由具有通过其内部的至少一部分形成的孔的主体构成的预灭菌装置。 孔内包含一个可移动的柱塞。 身体有第一和第二端。 第一端包含设计成连接到上游部件的面。 第二端连接到诸如过滤器，管道，样品袋等的下游部件。 柱塞具有相应的第一和第二端。 柱塞在其关闭位置时的第一端与主体的表面对齐，该表面组合形成一个可蒸汽表面，并且一个无菌隔离物抵抗环境的内部其余部分，柱塞和下游部件。 该装置连接到上游部件，柱塞的表面和第一端被蒸汽灭菌就位。
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公开(公告)号：US20110197989A1
公开(公告)日：2011-08-18
申请号：US13092566
申请日：2011-04-22
IPC分类号： B65B3/04
CPC分类号： F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要： The present invention relates to a process for the sterile transfer of fluids, be they liquids or gases. It uses a presterilized device comprised of a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to a downstream component such as a filter, pipeline, sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components. The device is attached to an upstream component and the face and the first end of the plunger are steam sterilized in place.
摘要翻译： 本发明涉及一种无菌转移流体（无论是液体还是气体）的方法。 它使用由具有通过其内部的至少一部分形成的孔的主体构成的预灭菌装置。 孔内包含一个可移动的柱塞。 身体有第一和第二端。 第一端包含设计成连接到上游部件的面。 第二端连接到诸如过滤器，管道，样品袋等的下游部件。 柱塞具有相应的第一和第二端。 柱塞在其关闭位置时的第一端与主体的表面对齐，该表面组合形成一个可蒸汽表面，并且一个无菌隔离物抵抗环境的内部其余部分，柱塞和下游部件。 该装置连接到上游部件，柱塞的表面和第一端被蒸汽灭菌就位。
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公开(公告)号：US08517998B2
公开(公告)日：2013-08-27
申请号：US13092566
申请日：2011-04-22
IPC分类号： A61M5/00
CPC分类号： F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要： The present invention relates to a process for the sterile transfer of fluids, be they liquids or gases. It uses a presterilized device comprised of a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to a downstream component such as a filter, pipeline, sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components. The device is attached to an upstream component and the face and the first end of the plunger are steam sterilized in place.
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公开(公告)号：US08579871B2
公开(公告)日：2013-11-12
申请号：US11584301
申请日：2006-10-20
IPC分类号： A61M5/00
CPC分类号： F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要： The present invention relates to a process for the sterile transfer of fluids, be they liquids or gases. It uses a presterilized device comprised of a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to a downstream component such as a filter, pipeline, sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components. The device is attached to an upstream component and the face and the first end of the plunger are steam sterilized in place.
摘要翻译： 本发明涉及一种无菌转移流体（无论是液体还是气体）的方法。 它使用由具有通过其内部的至少一部分形成的孔的主体构成的预灭菌装置。 孔内包含一个可移动的柱塞。 身体有第一和第二端。 第一端包含设计成连接到上游部件的面。 第二端连接到诸如过滤器，管道，样品袋等的下游部件。 柱塞具有相应的第一和第二端。 柱塞在其关闭位置时的第一端与主体的表面对齐，该表面组合形成一个可蒸汽表面，并且一个无菌隔离物抵抗环境的内部其余部分，柱塞和下游部件。 该装置连接到上游部件，柱塞的表面和第一端被蒸汽灭菌就位。
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公开(公告)号：US07927316B2
公开(公告)日：2011-04-19
申请号：US10500077
申请日：2003-04-25
IPC分类号： A61M5/00
CPC分类号： F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要： The present invention relates to a sterile transfer device for fluids, be they liquids or gases. It is comprised of a body having a bore formed through at least a portion of its interior. Preferably, it is a central bore formed through the entire length of the body. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to a downstream component such as a filter, pipeline, sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components.
摘要翻译： 本发明涉及用于流体的无菌转移装置，无论是液体还是气体。 它由具有通过其内部的至少一部分形成的孔的主体构成。 优选地，其是穿过身体的整个长度形成的中心孔。 孔内包含一个可移动的柱塞。 身体有第一和第二端。 第一端包含设计成连接到上游部件的面。 第二端连接到诸如过滤器，管道，样品袋等的下游部件。 柱塞具有相应的第一和第二端。 柱塞在其关闭位置时的第一端与主体的表面对齐，该表面组合形成一个可蒸汽表面，并且一个无菌隔离物抵抗环境的内部其余部分，柱塞和下游部件。
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公开(公告)号：US20050016620A1
公开(公告)日：2005-01-27
申请号：US10500077
申请日：2003-04-25
IPC分类号： B67D99/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , F16K3/26 , F16K15/18 , F16K17/40 , F16L37/107 , B65B1/04
CPC分类号： F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要： The present invention relates to a sterile transfer device for fluids, be they liquids or gases. It is comprised of a body having a bore formed through at least a portion of its interior. Preferably, it is a central bore formed through the entire length of the body. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to a downstream component such as a filter, pipeline, sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components.
摘要翻译： 本发明涉及用于流体的无菌转移装置，无论是液体还是气体。 它由具有通过其内部的至少一部分形成的孔的主体构成。 优选地，其是穿过身体的整个长度形成的中心孔。 孔内包含一个可移动的柱塞。 身体有第一和第二端。 第一端包含设计成连接到上游部件的面。 第二端连接到诸如过滤器，管道，样品袋等的下游部件。 柱塞具有相应的第一和第二端。 柱塞在其关闭位置时的第一端与主体的表面对齐，该表面组合形成一个可蒸汽表面，并且一个无菌隔离物抵抗环境的内部其余部分，柱塞和下游部件。
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公开(公告)号：US08562572B2
公开(公告)日：2013-10-22
申请号：US11350384
申请日：2006-02-08
IPC分类号： A61M5/00
CPC分类号： F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要： The present invention relates to a sterile sample collection device for fluids and a method of using the same. It is comprised of a transfer device having a body with a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to tube which is then connected to a collection bag. The plunger has corresponding first and second ends. The first end of the plunger when in the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components.
摘要翻译： 本发明涉及一种用于流体的无菌样品收集装置及其使用方法。 它由具有通过其内部的至少一部分形成的孔的本体的转移装置组成。 孔内包含一个可移动的柱塞。 身体有第一和第二端。 第一端包含设计成连接到上游部件的面。 第二端连接到管，然后连接到收集袋。 柱塞具有相应的第一和第二端。 当处于关闭位置时，柱塞的第一端与主体的表面对准，该表面组合形成可蒸发的表面，并且将抗环境的无菌屏障组合到主体内部的其余部分，柱塞和下游部件。
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公开(公告)号：US20060142730A1
公开(公告)日：2006-06-29
申请号：US11350384
申请日：2006-02-08
IPC分类号： A61B19/00
CPC分类号： F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要： The present invention relates to a sterile sample collection device for fluids and a method of using the same. It is comprised of a transfer device having a body with a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to tube which is then connected to a collection bag. The plunger has corresponding first and second ends. The first end of the plunger when in the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components.
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