Sdr proteins from staphylococcus capitis and their use in preventing and treating infections
    2.
    发明申请
    Sdr proteins from staphylococcus capitis and their use in preventing and treating infections 审中-公开
    来自葡萄球菌属capitis的Sdr蛋白及其在预防和治疗感染中的应用

    公开(公告)号:US20070026011A1

    公开(公告)日:2007-02-01

    申请号:US10558479

    申请日:2004-06-01

    摘要: An isolated and/or purified Sdr surface protein from S. capitis and nucleic acids encoding them are provided which includes the SdrX protein which possesses collagen binding activites and the SdrZL protein which possesses SdrZ-like properties. The Sdr surface proteins from S. capitis can be used in pharmaceutical compositions to treat and prevent S. capitis infectionm and can also be used in vaccines and to raise antibodies which can treat or prevent such infections. Because the SdrX protein has been shown to have collagen binding abilities, antibodies to SdrX will have the ability to inhibit or prevent the ability of S. capitis to bind to collagen.

    摘要翻译: 提供了一种分离的和/或纯化的来自头孢菌素的Sdr表面蛋白和编码它们的核酸,其包括具有胶原结合活性的SdrX蛋白和具有SdrZ样特性的SdrZL蛋白。 来自头孢菌素的Sdr表面蛋白质可用于药物组合物中以治疗和预防头孢菌素感染,并且还可用于疫苗和产生可治疗或预防这种感染的抗体。 由于SdrX蛋白已被证明具有胶原结合能力,因此对SdrX的抗体将具有抑制或预防人头颈炎结合胶原蛋白的能力的能力。

    Cotton leaf curl virus (CLCuV) promoter and its use
    4.
    发明授权
    Cotton leaf curl virus (CLCuV) promoter and its use 有权
    棉叶卷曲病毒(CLCuV)启动子及其用途

    公开(公告)号:US06610907B1

    公开(公告)日:2003-08-26

    申请号:US09936552

    申请日:2001-09-14

    IPC分类号: C12N1582

    摘要: The present invention is directed to a cotton leaf curl virus (CLCUV) bi-directional promoter, a method of expressing a heterologous gene in various plant tissues at a high level using the cotton leaf curl virus bi-directional promoter, and an AC2 protein factor from CLCuV genome to improve the expression level of the coat protein-coding gene promoter in the bi-directional promoter. The expression of a heterologous gene in plants is improved by using the materials and methods of the present invention.

    摘要翻译: 本发明涉及棉花卷曲病毒(CLCUV)双向启动子,使用棉花叶卷曲病毒双向启动子在高水平的各种植物组织中表达异源基因的方法,以及AC2蛋白因子 从CLCuV基因组提高双向启动子中外壳蛋白编码基因启动子的表达水平。 通过使用本发明的材料和方法,提高了植物中异源基因的表达。