公开(公告)号：US20070122419A1

公开(公告)日：2007-05-31

申请号：US10552330

申请日：2004-04-12

申请人： Joseph Witztum ,  Mi-Kyung Chung ,  Gregg Silverman ,  Peter Shaw ,  Christoph Binder

发明人： Joseph Witztum ,  Mi-Kyung Chung ,  Gregg Silverman ,  Peter Shaw ,  Christoph Binder

IPC分类号： A61K39/09 ,  A61K39/00 ,  A61K31/739

CPC分类号： A61K31/661 ,  A61K31/7028 ,  A61K39/0012 ,  A61K39/092 ,  A61K2039/505 ,  C07K16/18

摘要： During the progression of atherosclerosis, autoantibodies are induced to epitopes of oxidized low-density lipoprotein (OxLDL), and active immunization of hypercholesterolemic mice with OxLDL ameliorates athero-genesis. The present studies have identified anti-OXLDL autoantibodies that share complete genetic and structural identity with antibodies produced by anti-phosphorylcholine B-cell clone, T15.

摘要翻译： 在动脉粥样硬化进程期间，自身抗体被诱导为氧化低密度脂蛋白（OxLDL）的表位，并且用OxLDL主动免疫高胆固醇血小鼠改善动脉粥样硬化。 本研究已经鉴定出与抗磷酸胆碱B细胞克隆T15产生的抗体具有完全的遗传和结构同一性的抗OXLDL自身抗体。

公开(公告)号：US07082983B2

公开(公告)日：2006-08-01

申请号：US10331720

申请日：2002-12-27

申请人： Abdoul Coulibaly ,  Bouaziz Belibel ,  Christoph Binder

发明人： Abdoul Coulibaly ,  Bouaziz Belibel ,  Christoph Binder

IPC分类号： E06B9/56

CPC分类号： B60J1/2063 ,  B60R5/047 ,  E06B9/42 ,  E06B9/60

摘要： A window shade component group which includes a window shade supporting windup shaft with bearing devices for rotatably supporting opposite ends of the windup shaft. At least one of the bearing devices is provided with a blocking device, which is effective for maintaining a spring drive of the windup shaft in the wound position after assembly of the windup shaft. Following installation of the window shade component group in a motor vehicle or appropriate housing, the blocking device is releasable as an incident to actuation of the windup shaft.

公开(公告)号：US20130011857A1

公开(公告)日：2013-01-10

申请号：US13578582

申请日：2011-02-04

申请人： Christoph Binder ,  David Weismann

发明人： Christoph Binder ,  David Weismann

IPC分类号： G01N33/566

CPC分类号： A61K38/1709

摘要： The invention relates to complement Factor H for use in the prevention and treatment of oxidative stress disease conditions in a patient, the use of Factor H in the preparation of a pharmaceutical preparation, and methods of determining the specific binding of Factor H to MDA and/or MAA in a sample.

摘要翻译： 本发明涉及用于预防和治疗患者的氧化应激疾病状况的补体因子H，在制备药物制剂中使用因子H，以及确定因子H与MDA的特异性结合和/ 或MAA。