摘要:
During the progression of atherosclerosis, autoantibodies are induced to epitopes of oxidized low-density lipoprotein (OxLDL), and active immunization of hypercholesterolemic mice with OxLDL ameliorates athero-genesis. The present studies have identified anti-OXLDL autoantibodies that share complete genetic and structural identity with antibodies produced by anti-phosphorylcholine B-cell clone, T15.
摘要:
A method and apparatus for determining spatial locations of defects in a material are described. The method includes providing a plurality of electrodes in contact with a material, applying a sinusoidal voltage to a select number of the electrodes at a predetermined frequency, determining gain and phase angle measurements at other of the electrodes in response to applying the sinusoidal voltage to the select number of electrodes, determining impedance values from the gain and phase angle measurements, computing an impedance spectrum for an area of the material from the determined impedance values, and comparing the computed impedance spectrum with a known impedance spectrum to identify spatial locations of defects in the material.
摘要:
The present invention is based on the discovery of genetic polymorphisms that are associated with cardiovascular disorders, particularly acute coronary events such as myocardial infarction and stroke, and genetic polymorphisms that are associated with responsiveness of an individual to treatment of cardiovascular disorders with statin. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
摘要:
The invention concerns the use of 5-hydroxy-3-thiazolidine-2-thiones of the structure I ##STR1## where R.sub.1 =(CHOH).sub.m, R.sub.2 =(CHOH).sub.n where (m+n)=0 to 6, and R.sub.3 is alkyl or hydroxy-alkyl as depressants in the flotation of mixtures of base metal minerals, particularly those containing molybdenum, copper, lead, zinc; and to flotation processes using these compounds.
摘要:
The present invention describes polynucleotides that have been discovered to correlate to the relative sensitivity or resistance of cells, e.g., breast cell lines, to treatment with compounds that interact with and modulate, e.g., inhibit, protein tyrosine kinases, such as, for example, members of the Src family of tyrosine kinases, e.g., Src, Fgr, Fyn, Yes, Blk, Hck, Lck and Lyn, as well as other protein tyrosine kinases, including, Bcr-abl, Jak, PDGFR, c-kit and Eph receptors. These polynucleotides have been shown to have utility in predicting the resistance and sensitivity of breast cell lines to the compounds. Such polynucleotides comprise polynucleotide predictor or marker sets useful in methods of predicting drug response, and as prognostic or diagnostic indicators in disease management, particularly in those disease areas, e.g., breast cancer, in which signaling through one or more of the aforementioned Src tyrosine and protein tyrosine kinases is involved with the disease process.
摘要:
A lift drive comprising: a spiral drive element having an axis of rotation, a rack having teeth sized and shaped to be engaged by the spiral drive element, the rack having a longitudinal axis parallel to the axis of rotation, and a motor to rotate the spiral drive element, wherein upon the spiral drive element-rotating, one of the spiral drive element and the rack moves relative to the other along the longitudinal axis.
摘要:
A stair lift for lifting and lowering at least one person on a rail on a stairway. There is a carriage mountable to the rail, the carriage having a track engaging drive, and a motor to power the drive, the powered drive causing the carriage to move along the rail. There is a central support post mounted on the carriage and an offset arm connected to the seat support post. The offset arm is mounted to the carriage in one of a left side or a right side position. A seat is mounted on the offset arm, and a notched plate secures the seat in position on the offset arm in either the left side or right side position and permits the seat to swivel between a sideways facing position and an upward facing position to facilitate the person getting into and out of the seat.
摘要:
A disposable microwave food shield for preventing splatter of food onto the interior surfaces of microwave ovens made from absorbent, yet rigid paper material.
摘要:
A lift drive comprising: a spiral drive element having an axis of rotation, a rack having teeth sized and shaped to be engaged by the spiral drive element, the rack having a longitudinal axis parallel to the axis of rotation, and a motor to rotate the spiral drive element, wherein upon the spiral drive element-rotating, one of the spiral drive element and the rack moves relative to the other along the longitudinal axis.
摘要:
A device and method are provided for protecting the inside of a microwave oven from food splattering during cooking. The device is made of breathable food grade paper, is a truncated cone in shape with a pleated side wall for rigidity and at least one reinforcing structure on a top surface. Top surface reinforcement may be one or more folded paper reinforcement bars or folded paper reinforcement members, shaped as circles, squares, or any other convenient shape. Reinforcement bars may be radial across the top surface or nonradial, and may be linear or curvilinear. The food shield device is made by conventional paper die stamping methods.