摘要:
A method, system, apparatus, and computer-readable medium are provided for exposing and utilizing property values maintained at a server computer. A request is received at the server computer for a resource, such as a Web page. In response to receiving the request, a determination is made by the server computer as to whether a property value maintained at the server computer should be returned with the resource. If the property value should be returned with the resource, the current value of the specified property is retrieve and is rendered into the resource as a variable statement specifying the current value of the property. The resource, including the variable statement, is then returned to the requesting application where it may be utilized.
摘要:
A method, system, and apparatus for implementing object interfaces at runtime are provided. According to the method, a request is received for a resource that includes a client side object that supports an object interface. In response to the request, program code is generated that implements the interface. Once the program code implementing the object interface has been generated, the requested resource and the program code implementing the object interface are returned in response to the request for the resource. An intermediary object for mediating communication between objects is also generated and returned in response to the request. If the object interface implements an interface for consuming data, the object interface registers itself with the intermediary object as an event consumer. If the object interface implements a provider interface, the object interface calls the intermediary object in response to the occurrence of a specified type of event.
摘要:
A method, system, and apparatus for customizing web part objects. A web part object 28 that is capable of providing a presentation is accessed. Once the web part object is accessed, a specification file 38 associated with the web part object is also accessed. The specification file contains additional code, such as HTML, JAVA Script, or other code. The additional code is applied to a web part to modify the presentation of the web part. Thus, the presentation of the web part is modified in accordance with the specification file to provide a modified presentation.
摘要:
A method for calendaring an activity based on roles, including the steps of acquiring a request for calendaring the activity for a plurality of roles invited to attend the activity; acquiring data on existing activities which have been calendared for all the specific individuals in the plurality of roles invited to attend the activity; and determining the time interval for holding the activity based on the data on existing activities which have been calendared for all the specific individuals in the plurality of roles invited to attend the activity and the request for calendaring the activity.
摘要:
The invention provides methods for determining the activity of a plurality of nucleic acid regulatory elements. These methods may facilitate, e.g., the systematic reverse engineering, and optimization of mammalian cis-regulatory elements at high resolution and at a large scale. The method may include integration of multiplexed DNA synthesis and sequencing technologies to generate and quantify the transcriptional regulatory activity of e.g., thousands of arbitrary DNA sequences in parallel in cell-based as says (e.g., mammalian cell based assays).
摘要:
Methods for alleviating the suppression of humoral immunity by myeloid-dependent suppressor cells (MDSCs) are provided which include the administration of a VISTA antagonist and an iNOS/NO inhibitor in a subject in need thereof, e.g., subjects with cancer or infectious disease wherein VISTA is aberrantly expressed. This combination has been discovered to elicit a synergistic or additive effect on alleviating suppression of humoral immunity by VISTA which is elicited by MDSCs.
摘要:
Disclosed are Dpo4 DNA polymerase mutants with increased DNA synthesis processivity. The mutant enzymes, Dpo4 A181D and Dpo4 E63K, are constructed based on the wild-type Dpo4 derived from Sulfolobus solfataricus to obtain Dpo4DNA polymerase mutants with increased DNA processivity. The extension length of Dpo4 A181D and Dpo4 E63K are respectively increased by 25% and 18.8% than that of the wild-type Dpo4. The fidelity of Dpo4 A181D and wild-type Dpo4 are similar, and the fidelity of Dpo4 E63K is increased from that of the wild-type Dpo4. In summary, the mutants Dpo4 A181D and Dpo4 E63K obtained by the present invention have increased processivity compared to that of the wild-type Dpo4 DNA polymerase.
摘要:
Embodiments of the present disclosure are directed to a heat exchange device that includes a condenser configured to receive a refrigerant, an evaporator having an evaporation tube bundle, a throttling device configured to receive a first portion of the refrigerant from the condenser and to expand the first portion of the refrigerant before directing the first portion to the evaporator, and an ejector having a high pressure conduit, a low pressure conduit, and an outlet conduit, the ejector is configured to receive the first portion from the throttling device or a second portion of the refrigerant from the condenser via the high pressure conduit, receive a third portion of the refrigerant from the evaporator via the low pressure conduit, mix the first portion or the second portion with the third portion to form a mixed refrigerant, and direct the mixed refrigerant to the evaporator via the outlet conduit.
摘要:
Aspects of this disclosure describe measuring intervals within a cardiac cycle to, for example, determine whether a patient is a candidate for cardiac therapy initiation or modification. The intervals may be measured in response to a trigger identifying a physiological event. The intervals and an identification of the physiological event may be stored. A physician or clinician may determine whether the patient is a candidate for cardiac therapy modification based on the measured intervals.