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38 条记录 (耗时 0.062 秒)

    Assays for detecting pregnancy-associated glycoproteins
    3.
    发明授权
    Assays for detecting pregnancy-associated glycoproteins 有权
    检测妊娠相关糖蛋白的分析

    公开(公告)号：US08192946B2

    公开(公告)日：2012-06-05

    申请号：US12422231

    申请日：2009-04-10

    申请人： Jonathan Green ,  Bhanu Prakash Telugu

    发明人： Jonathan Green ,  Bhanu Prakash Telugu

    IPC分类号： C12Q1/37

    CPC分类号： C12Q1/37 ,  G01N2333/96416 ,  G01N2800/36

    摘要： Disclosed are methods and compositions for detecting pregnancy in an animal by means of assaying peptidase activity of one or more Pregnancy Associated Glycoproteins (PAGs). In certain aspects, methods also comprising use of an antibody that binds immunologically to a PAG that displays proteolytic activity are provided. Substrates of proteolytic PAGs are also provided, as are kits, and methods of use. Further, methods of purifying PAGs based on their proteolytic activity are also provided.

    摘要翻译： 公开了通过测定一种或多种妊娠相关糖蛋白（PAG）的肽酶活性来检测动物中怀孕的方法和组合物。 在某些方面，提供了还包括使用与显示蛋白水解活性的PAG免疫学结合的抗体的方法。 还提供蛋白水解PAG的底物，试剂盒和使用方法。 此外，还提供了基于其蛋白水解活性来纯化PAG的方法。

    UNIFIED COMMUNICATION SYSTEM
    5.
    发明申请
    UNIFIED COMMUNICATION SYSTEM 审中-公开
    统一通信系统

    公开(公告)号：US20110015930A1

    公开(公告)日：2011-01-20

    申请号：US12876514

    申请日：2010-09-07

    申请人： John Ward ,  Haydar Haba ,  Charles Studt ,  Peter Antypas ,  Jonathan Green

    发明人： John Ward ,  Haydar Haba ,  Charles Studt ,  Peter Antypas ,  Jonathan Green

    IPC分类号： G10L13/08

    CPC分类号： H04M3/42229 ,  H04M3/5307 ,  H04M2203/2061 ,  H04M2203/4509 ,  H04M2207/20

    摘要： A unified communication system is disclosed that allows a variety of end point types to participate in a communication event using a common, unified communication system. In some implementations, a calling party interacts with a client application residing on an endpoint to make a communication request to another endpoint. A communication event manager residing in the unified communication system selects a script from a repository of scripts based on the communication event and the capabilities of the endpoints. A communication event execution engine receives a user profile associated with at least one of the endpoints. The user profile can be configured by the user to describe the user's preferences for how the communication should be processed by the unified communication system.

    摘要翻译： 公开了统一的通信系统，其允许各种端点类型使用公共的统一通信系统来参与通信事件。 在一些实现中，主叫方与驻留在端点上的客户端应用进行交互以向另一端点发送通信请求。 驻留在统一通信系统中的通信事件管理器基于通信事件和端点的能力从脚本存储库中选择脚本。 通信事件执行引擎接收与至少一个端点相关联的用户简档。 用户配置文件可以由用户配置，以描述用户对统一通信系统如何处理通信的偏好。

    Unified Communication System
    6.
    发明申请
    Unified Communication System 审中-公开
    统一通信系统

    公开(公告)号：US20110007732A1

    公开(公告)日：2011-01-13

    申请号：US12499607

    申请日：2009-07-08

    申请人： John Ward ,  Haydar Haba ,  Charles Studt ,  Peter Antypas ,  Jonathan Green

    发明人： John Ward ,  Haydar Haba ,  Charles Studt ,  Peter Antypas ,  Jonathan Green

    IPC分类号： H04L12/66 ,  G10L19/00

    CPC分类号： H04M3/42229 ,  H04M3/5307 ,  H04M2203/2061 ,  H04M2203/4509 ,  H04M2207/20

    摘要： A unified communication system is disclosed that allows a variety of end point types to participate in a communication event using a common, unified communication system. In some implementations, a calling party interacts with a client application residing on an endpoint to make a communication request to another endpoint. A communication event manager residing in the unified communication system selects a script from a repository of scripts based on the communication event and the capabilities of the endpoints. A communication event execution engine receives a user profile associated with at least one of the endpoints. The user profile can be configured by the user to describe the user's preferences for how the communication should be processed by the unified communication system.

    摘要翻译： 公开了统一的通信系统，其允许各种端点类型使用公共的统一通信系统来参与通信事件。 在一些实现中，主叫方与驻留在端点上的客户端应用进行交互以向另一端点发送通信请求。 驻留在统一通信系统中的通信事件管理器基于通信事件和端点的能力从脚本存储库中选择脚本。 通信事件执行引擎接收与至少一个端点相关联的用户简档。 用户配置文件可以由用户配置，以描述用户对统一通信系统如何处理通信的偏好。

    Topically administrable pharmaceutical preparations
    9.
    发明授权
    Topically administrable pharmaceutical preparations 失效
    主要管理药物制剂

    公开(公告)号：US5133972A

    公开(公告)日：1992-07-28

    申请号：US546345

    申请日：1990-06-29

    申请人： Pier G. Ferrini ,  Carlo Voellmy ,  Peter H. Stahl ,  Jonathan Green

    发明人： Pier G. Ferrini ,  Carlo Voellmy ,  Peter H. Stahl ,  Jonathan Green

    IPC分类号： A61K9/00 ,  A61K9/70 ,  A61K31/66 ,  A61K31/675 ,  A61P17/00 ,  A61P43/00 ,  C07F9/38

    CPC分类号： A61K9/7053 ,  A61K31/66 ,  A61K31/675 ,  A61K9/7061 ,  A61K9/7076 ,  A61K9/7084

    摘要： The invention relates to topically adminstrable pharmaceutical preparations containing pharmaceutically acceptable methanediphosphonic acid derivatives of formula ##STR1## and their salts, wherein each of R.sub.1 and R.sub.2 is halogen, or wherein R.sub.1 is hydrogen and R.sub.2 is Ar--S-- or Het.sub.1 --NH--, in which Ar is unsubstituted or substituted phenyl and Het.sub.1 is unsubstituted or substituted, monocyclic, 5- or 6-membered monoaza-, diaza- or thiaza-aryl that is bonded via a ring carbon atom, or wherein R.sub.1 is hydrogen or hydroxy and R.sub.2 is --A--R.sub.3, in which A is alkylene and, on the one hand, R.sub.3 is Het.sub.2, which is Het.sub.1 bonded via a ring carbon or ring nitrogen atom, or, on the other hand, R.sub.3 is hydrogen, or amino that is unsubsituted or mono- or di-substituted by identical or different substituents selected from alkyl, cycloalkyl, Ar-alkyl, Ar-O-alkyl, Ar-S-alkyl and Het.sub.1 -alkyl, or that is disubstituted by optionally Ar-containing alkylene, wherein two alkylene carbon atoms mar additionally be linked to one another via alkylene and Ar and Het.sub.1 are each as defined above, with the proviso that when R.sub.2 is --A--R.sub. 3, A is ethylene and R.sub.3 is unsubstituted or C.sub.1 -C.sub.3 alkyl-substituted amino, R.sub.1 is other than hydroxy.

    摘要翻译： 本发明涉及含有药学上可接受的式（I）的甲二膦酸衍生物及其盐的局部给药药物制剂，其中R1和R2各自为卤素，或其中R1为氢，R2为Ar-S-或Het1- NH-，其中Ar是未取代或取代的苯基，Het1是未经取代或取代的单环，5或6元单氮杂，二氮杂 - 或噻唑基 - 芳基，其通过环碳原子键合，或其中R1是氢或 羟基和R 2是-A-R 3，其中A是亚烷基，一方面，R 3是Het 2，其是通过环碳或环氮原子键合的Het1，或者另一方面，R 3是氢，或 未被取代或被相同或不同的选自烷基，环烷基，Ar-烷基，Ar-O-烷基，Ar-S-烷基和Het1 - 烷基的取代基取代或被取代的氨基，或被任意Ar- 其中两个亚烷基碳原子另外与一个a连接 通过亚烷基，Ar和Het1各自如上所定义，条件是当R 2是-A-R 3时，A是亚乙基，R 3是未取代的或C 1 -C 3烷基取代的氨基，R 1不是羟基。

    Folded sheet dispenser with overfill prevention device
    10.
    发明授权
    Folded sheet dispenser with overfill prevention device 有权
    具有防溢流装置的折页机

    公开(公告)号：US08851326B2

    公开(公告)日：2014-10-07

    申请号：US13274957

    申请日：2011-10-17

    申请人： Paul Francis Tramontina ,  Jonathan Green ,  Wolfgang Heich

    发明人： Paul Francis Tramontina ,  Jonathan Green ,  Wolfgang Heich

    IPC分类号： B65D83/08

    CPC分类号： A47K10/424

    摘要： The present invention provides a dispenser for folded sheets having an overfill prevention device, which effectively prevents the dispenser from being overfilled with folded sheet material. The result of the present invention is that a maintainer of the dispenser will have a difficult time overfilling the dispenser.

    摘要翻译： 本发明提供一种用于折叠片材的分配器，其具有防溢出装置，其有效地防止分配器被折叠的片材过度填充。 本发明的结果是分配器的维护者将难以超过分配器的时间。