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    Novel Statin Pharmaceutical Compositions and Related Methods of Treatment
    4.
    发明申请
    Novel Statin Pharmaceutical Compositions and Related Methods of Treatment 审中-公开
    新型他汀类药物组合物及相关治疗方法

    公开(公告)号：US20090042979A1

    公开(公告)日：2009-02-12

    申请号：US12184888

    申请日：2008-08-01

    申请人： Hector Guzman ,  Orn Almarsson ,  Julius Remenar

    发明人： Hector Guzman ,  Orn Almarsson ,  Julius Remenar

    IPC分类号： A61K31/21 ,  A61P9/10

    CPC分类号： A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  A61K31/21 ,  A61K31/22 ,  A61K31/405 ,  A61K45/06 ,  A61K47/12 ,  A61K2300/00

    摘要： The invention provides novel omega-3 oil formulations of one or more statins. These formulations are readily bioavailable. Notably, because the formulations of the invention contain an omega-3 oils as the major ingredient, they not only provide an antihypercholesterolemic effect due to the statin active ingredient, they also provide recommended daily dosages of omega-3 oils (i.e., approximately 1 gram of omega-3 oil per day), or a portion thereof. The invention also provides novel salts of one or more statins.

    摘要翻译： 本发明提供一种或多种他汀类的新型ω-3油制剂。 这些制剂容易生物利用。 值得注意的是，由于本发明的制剂含有ω-3油作为主要成分，它们不仅由于他汀类活性成分而提供抗高胆固醇血症作用，而且还提供推荐的每日剂量的ω-3油（即约1克 的ω-3油）或其一部分。 本发明还提供一种或多种他汀类药物的新型盐。

    Novel statin pharmaceutical compositions and related methods of treatment
    8.
    发明申请
    Novel statin pharmaceutical compositions and related methods of treatment 失效
    新型他汀类药物组合物及相关治疗方法

    公开(公告)号：US20060034815A1

    公开(公告)日：2006-02-16

    申请号：US11197880

    申请日：2005-08-05

    申请人： Hector Guzman ,  Julius Remenar ,  Orn Almarsson

    发明人： Hector Guzman ,  Julius Remenar ,  Orn Almarsson

    IPC分类号： A61K38/43

    CPC分类号： A61K31/201 ,  A61K31/20 ,  A61K31/202 ,  A61K31/22 ,  A61K31/405 ,  A61K45/06 ,  A61K47/12 ,  A61K2300/00

    摘要： The invention provides novel omega-3 oil solutions of one or more statins. These solutions are readily bioavailable. Notably, because the solutions of the invention contain an omega-3 oil as the major ingredient, they not only provide an antihypercholesterolemic effect due to the statin active ingredient, they also provide recommended daily dosages of omega-3 oils (i.e., approximately 1 gram of omega-3 oil per day), or a portion thereof. The invention also provides novel salts of one or more statins.

    摘要翻译： 本发明提供一种或多种他汀类的新型ω-3油溶液。 这些解决方案很容易生物利用。 值得注意的是，由于本发明的溶液含有ω-3油作为主要成分，它们不仅由于他汀类活性成分而提供抗高胆固醇血症作用，而且还提供推荐的每日剂量的ω-3油（即约1克 的ω-3油）或其一部分。 本发明还提供一种或多种他汀类药物的新型盐。

    Novel Saperconazole Crystalline Forms and Related Processes, Pharmaceutical Compositions and Methods
    10.
    发明申请
    Novel Saperconazole Crystalline Forms and Related Processes, Pharmaceutical Compositions and Methods 审中-公开
    新型沙伯康唑结晶形式及相关工艺，药物组合物和方法

    公开(公告)号：US20070293674A1

    公开(公告)日：2007-12-20

    申请号：US11568131

    申请日：2005-04-21

    申请人： Lisa Scoppettuolo ,  Matthew Peterson ,  Orn Almarsson ,  Julius Remenar

    发明人： Lisa Scoppettuolo ,  Matthew Peterson ,  Orn Almarsson ,  Julius Remenar

    IPC分类号： C07D403/14

    CPC分类号： C07D405/14 ,  A61K31/496

    摘要： The invention provides novel soluble conazole crystalline forms (e.g., cisitraconazole, saperconazole) that include salts, co-crystals and polymorphs useful as pharmaceuticals. The invention also provides pharmaceutical compositions comprising, and processes for making, these conazole crystalline forms. Methods of using such compositions for the treatment or prevention of systemic and local fungal, yeast, and dermatophyte infections are also provided.

    摘要翻译： 本发明提供了可用作药物的盐，共晶和多晶型物的新型可溶性唑型结晶形式（例如顺硝霉唑，沙伯康唑）。 本发明还提供药物组合物，其包含和制备这些azole唑晶型。 还提供了使用这些组合物来治疗或预防全身和局部真菌，酵母和皮肤癣菌感染的方法。