公开(公告)号：US20060199029A1

公开(公告)日：2006-09-07

申请号：US11317682

申请日：2005-12-23

申请人： Junkang Liu ,  Mark Pellerite ,  George Moore ,  Michael Semonick

发明人： Junkang Liu ,  Mark Pellerite ,  George Moore ,  Michael Semonick

IPC分类号： B32B27/00

CPC分类号： C08F220/18 ,  C08F220/24 ,  C08F220/30 ,  C08K5/06 ,  C08K5/101 ,  C09D133/16 ,  C09J133/16 ,  Y10T428/31855 ,  C08L33/16

摘要： In one aspect, the invention provides a fluorochemical composition comprising a mixture of: a fluorochemical selected from the formula: wherein RF is a fluorinated group having the formula: Rf—W—, wherein Rf is a perfluoroalkyl or perfluoropolyether group and W is a divalent linking group; PI is a monovalent pendant organic moiety comprising benzophenone, substituted benzophenone, acetophenone, or substituted acetophenone groups; R is H, CH3, or F; Rh is lower alkyl selected from the group consisting of linear or branched alkyl groups having from 1 to about 8 carbon atoms, cycloalky containing alkyl groups having from 4 to about 8 carbon atoms, and cycloalkyl groups having from 3 to about 8 carbon atoms, all optionally containing catenated O or N atoms; m is at least 2; n is at least 1; q is zero or greater; and a hydrofluoroether.

摘要翻译： 一方面，本发明提供一种含氟化合物组合物，其包含以下混合物的混合物：选自下式的含氟化合物：其中RF是具有下式的氟化基团：其中R 1，R 2， f是全氟烷基或全氟聚醚基团，W是二价连接基团; PI是包含二苯甲酮，取代的二苯甲酮，苯乙酮或取代的苯乙酮基团的单价侧基有机部分; R是H，CH 3或F; Rh是选自具有1至约8个碳原子的直链或支链烷基，含有4至约8个碳原子的含环烷基的烷基和具有3至约8个碳原子的环烷基的低级烷基，全部 任选地含有连接的O或N原子; m至少为2; n至少为1; q为零或更大; 和氢氟醚。

公开(公告)号：US20070197470A1

公开(公告)日：2007-08-23

申请号：US10572113

申请日：2003-09-17

申请人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

发明人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

IPC分类号： A61K31/7008 ,  A61K9/12

CPC分类号： A61K31/7008

摘要： The present invention has disclosed a use of N-acetyl-D-glucosamine in the preparation of a medicament for regulating microecological balance of mucocutaneous membrane. N-acetyl-D-glucosamine has functions of promoting bacteria and cellular redistribution and against allochthonous flora colonization. Preparations comprising N-acetyl-D-glucosamine as main active substance are able to be used for regulating microecological balance of mucocutaneous membrane, and have advantages of significant therapeutic effects, simple manufacture, nonirritant, non-pollution, etc.

摘要翻译： 本发明公开了N-乙酰基-D-葡糖胺在制备用于调节粘膜皮肤膜的微生态平衡的药物中的用途。 N-乙酰基-D-葡糖胺具有促进细菌和细胞再分配和抗同种异体植物群定植的功能。 包含N-乙酰基-D-葡糖胺作为主要活性物质的制剂能够用于调节皮肤膜的微生态平衡，具有显着的治疗效果，制造简单，无刺激性，无污染等优点。

公开(公告)号：US07345030B2

公开(公告)日：2008-03-18

申请号：US10551091

申请日：2004-03-29

申请人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

发明人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

IPC分类号： A61K31/70 ,  C07H5/04

CPC分类号： A61K31/7008

摘要： The present invention is directed to the use of N-acetyl-D-glucosamine to treat organ lesions caused by toxicants and drugs. The present invention is also directed to a method for treating organ lesions caused by toxicant comprising administering to a patient suffering from organ lesions a pharmaceutical composition comprising N-acetyl-D-glucosamine or a pharmaceutically acceptable salt thereof.

摘要翻译： 本发明涉及N-乙酰基-D-葡糖胺用于治疗由毒物和药物引起的器官损害的用途。 本发明还涉及一种用于治疗由毒物引起的器官损害的方法，包括向患有器官损害的患者施用包含N-乙酰基-D-葡糖胺或其药学上可接受的盐的药物组合物。

公开(公告)号：US20070178161A1

公开(公告)日：2007-08-02

申请号：US10551258

申请日：2004-03-29

申请人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

发明人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

IPC分类号： A61K31/7008 ,  A61K9/14

CPC分类号： A61K31/7008

摘要： The present invention relates to a use of N-acetyl-D-glucosamine in the manufacture of a medicament for treating non-specific inflammations caused by physical/chemical factors and controlling symptoms thereof. A preparation comprising N-acetyl-D-glucosamine as main active component for treating non-specific inflammations caused by physical/chemical factors exhibits merits of significant therapeutical effects and simple manufacture and has no side effect.

摘要翻译： 本发明涉及N-乙酰基-D-葡糖胺在制备用于治疗由物理/化学因素引起的非特异性炎症并控制其症状的药物中的用途。 作为用于治疗由物理/化学因素引起的非特异性炎症的N-乙酰基-D-葡糖胺作为主要活性成分的制剂，具有显着的治疗效果和制造简单的优点，并且没有副作用。

公开(公告)号：US20070160527A1

公开(公告)日：2007-07-12

申请号：US10551081

申请日：2004-03-29

申请人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

发明人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

IPC分类号： A61K51/00

CPC分类号： A61K31/7008

摘要： The present invention discloses a method for treating local lesions or systematic symptoms caused by autoimmune reactions, a use of N-acetyl-D-glucosamine for treating local lesions or systematic symptoms caused by autoimmune reactions, and a use of N-acetyl-D-glucosamine in the manufacture of a medicament for treating local lesions or systematic symptoms caused by autoimmune reactions.

摘要翻译： 本发明公开了一种治疗由自身免疫反应引起的局部病变或系统症状的方法，使用N-乙酰基-D-葡糖胺治疗局部病变或由自身免疫反应引起的系统症状，以及使用N-乙酰基-D- 葡糖胺制造用于治疗由自身免疫反应引起的局部损害或系统症状的药物。

公开(公告)号：US20060281707A1

公开(公告)日：2006-12-14

申请号：US10551091

申请日：2004-03-29

申请人： Qiwang Xu ,  Junkang Liu

发明人： Qiwang Xu ,  Junkang Liu

IPC分类号： A61K31/7008

CPC分类号： A61K31/7008

摘要： The present invention discloses a use of N-acetyl-D-glucosamine in the manufacture of a medicament for treating organ lesions caused by toxicants and drugs. A preparation comprising N-acetyl-D-glucosamine as main active component for treating organ lesions caused by toxicants and drugs exhibits merits of a directive action mechanism, significant therapeutical effects and simple manufacture and has no side effect.

摘要翻译： 本发明公开了N-乙酰基-D-葡糖胺在制备用于治疗由毒物和药物引起的器官损害的药物中的用途。 作为用于治疗由毒物和药物引起的器官损害的主要活性成分的N-乙酰基-D-葡糖胺的制剂，具有指导作用机制，显着的治疗效果和制造简单的优点，没有副作用。

公开(公告)号：US07015207B2

公开(公告)日：2006-03-21

申请号：US10469325

申请日：2002-02-28

申请人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

发明人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

IPC分类号： A01N43/04 ,  A61K31/70

CPC分类号： A61K31/7008

摘要： The present invention has disclosed a use of N-acetyl-D-glucosamine in the preparation of a medicine for preventing and treating the sexual disfunction. The preparation taken N-acetyl-D-glucosamine as a main active component has been used to prevent and cure the sexual disfunction, and has the merits of remarkable curative effect, easy to prepare, no side effect and so on.

摘要翻译： 本发明公开了N-乙酰基-D-葡糖胺在制备用于预防和治疗性功能障碍的药物中的用途。 以N-乙酰基-D-葡萄糖胺为主要成分的制剂已被用于预防和治疗性功能障碍，具有疗效显着，易于准备，无副作用等优点。

公开(公告)号：US20070191291A1

公开(公告)日：2007-08-16

申请号：US10572226

申请日：2003-09-18

申请人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

发明人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

IPC分类号： A61K31/7048 ,  A61K31/7034 ,  A61K31/7008 ,  A61K31/496 ,  A61K31/4709 ,  A61K31/65 ,  A61K31/43 ,  A61K31/545

CPC分类号： A61K45/06 ,  A61K31/43 ,  A61K31/4704 ,  A61K31/545 ,  A61K31/65 ,  A61K31/7008 ,  A61K31/7036 ,  A61K31/7048 ,  A61K2300/00

摘要： The use of the combination of N-acetyl-D-glucosamine and antibiotics for the preparation of antibacterial drugs is disclosed. In the therapies of infections with antibiotics, the pathogens may be changed into slender shaped forms called cryptic growth cells (CGCs), CGCs can colonize and thereby physiological drug resistance arises. In the meantime, normal bacteria colonies in the body may be also changed into CGCs upon administration of antibiotics. These changes result in complications after the therapies, such as disorder of bacteria colonies in the body, disorder of GI functions and other chronic diseases. The combination of antibiotics and N-acetyl-D-aminoglycosamine can prevent of CGC, and the complications after antibiotics therapy.

摘要翻译： 公开了使用N-乙酰基-D-葡糖胺和抗生素的组合来制备抗菌药物。 在用抗生素感染的治疗中，病原体可能会变成细长形状称为隐窝生长细胞（CGC），CGC可以定居，从而产生生理耐药性。 同时，在施用抗生素后，身体中的正常细菌菌落也可以变成CGC。 这些变化导致治疗之后的并发症，例如身体细菌菌落紊乱，GI功能障碍和其他慢性疾病。 抗生素与N-乙酰基-D-氨基糖胺的组合可以预防CGC，以及抗生素治疗后的并发症。

公开(公告)号：US20070042995A1

公开(公告)日：2007-02-22

申请号：US10550784

申请日：2004-03-29

申请人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

发明人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

IPC分类号： A61K31/7008

CPC分类号： A61K31/7008

摘要： The present invention discloses a use of N-acetyl-D-glucosamine or pharmaceutically acceptable salts thereof in the manufacture of a medicament for treating local lesions or systematic symptoms caused by infections of virus or bacteria. A parenteral preparation comprising N-acetyl-D-glucosamine or pharmaceutically acceptable salts thereof as active component is capable of controlling systematic toxic symptoms caused by infections of virus and bacteria and local and systematic lesions caused by endotoxins and exotoxins, and exhibits an excellence rate of 90%.

摘要翻译： 本发明公开了N-乙酰基-D-葡糖胺或其药学上可接受的盐在制备用于治疗由病毒或细菌感染引起的局部损害或系统症状的药物中的用途。 包含N-乙酰基-D-葡糖胺或其药学上可接受的盐作为活性组分的肠胃外制剂能够控制由病毒和细菌感染引起的系统性毒性症状以及由内毒素和外毒素引起的局部和系统性病变，并显示出优异的 90％。

公开(公告)号：US06946452B2

公开(公告)日：2005-09-20

申请号：US10469326

申请日：2002-02-28

申请人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

发明人： Qiwang Xu ,  Junkang Liu ,  Zetao Yuan

IPC分类号： A61K31/7008 ,  A61P1/08 ,  A01N43/04 ,  A61K31/70

CPC分类号： A61K31/7008

摘要： The present invention has disclosed a use of N-acetyl-D-glucosamine in the manufacture of a medicament for preventing and treating motion sickness, the preparation in which N-acetyl-D-glucosamine is taken as a main active component is able to be used for preventing and treating motion sickness with an effective rate up to more than 90%.

摘要翻译： 本发明公开了N-乙酰基-D-葡糖胺在制备用于预防和治疗晕车病的药物中的用途，其中N-乙酰基-D-葡糖胺作为主要活性成分的制剂能够是 用于预防和治疗晕车，有效率高达90％以上。