公开(公告)号：US10010598B2

公开(公告)日：2018-07-03

申请号：US15824694

申请日：2017-11-28

Applicant: KANSAS STATE UNIVERSITY RESEARCH FOUNDATION

Inventor： Sanjeev Narayanan ,  Amit Kumar ,  Tiruvoor Nagaraja ,  Muckatira Chengappa

IPC: A61K39/39 ,  A61K39/114 ,  C07K14/195

CPC classification number: A61K39/114 ,  A61K39/39 ,  C07K14/195

Abstract: The present invention relates to protecting against, treating, and detecting Fusobacteria infections. Compositions and methods derived from nucleic acid and protein sequences of a 40 kDa Adhesin protein are provided to protect against, treat, and detect Fusobacteria infections in a subject. In one aspect, vaccines capable of inducing an immune response to a 40 kDa Adhesin protein are used to protect against Fusobacteria infection. Also, nucleic acid molecules, proteins, immunogens, antibodies, and antisense molecules derived from the sequences of the 40 kDa Adhesin protein may be used to protect against, treat, and detect Fusobacteria infections in a subject.

公开(公告)号：US09884102B2

公开(公告)日：2018-02-06

申请号：US15052594

申请日：2016-02-24

Applicant: KANSAS STATE UNIVERSITY RESEARCH FOUNDATION

Inventor： Sanjeev Narayanan ,  Amit Kumar ,  Tiruvoor Nagaraja ,  Muckatira Chengappa

IPC: C07K14/195 ,  A61K39/114 ,  A61K39/39

CPC classification number: A61K39/114 ,  A61K39/39 ,  C07K14/195

Abstract: The present invention relates to protecting against, treating, and detecting Fusobacteria infections. Compositions and methods derived from nucleic acid and protein sequences of a 40 kDa Adhesin protein are provided to protect against, treat, and detect Fusobacteria infections in a subject. In one aspect, vaccines capable of inducing an immune response to a 40 kDa Adhesin protein are used to protect against Fusobacteria infection. Also, nucleic acid molecules, proteins, immunogens, antibodies, and antisense molecules derived from the sequences of the 40 kDa Adhesin protein may be used to protect against, treat, and detect Fusobacteria infections in a subject.

公开(公告)号：US10220085B2

公开(公告)日：2019-03-05

申请号：US15961996

申请日：2018-04-25

Applicant: KANSAS STATE UNIVERSITY RESEARCH FOUNDATION

Inventor： Sanjeev Narayanan ,  Amit Kumar ,  Tiruvoor Nagaraja ,  Muckatira Chengappa

IPC: A61K39/39 ,  A61K39/114 ,  C07K14/195

Abstract: The present invention relates to protecting against, treating, and detecting Fusobacteria infections. Compositions and methods derived from nucleic acid and protein sequences of a 40 kDa Adhesin protein are provided to protect against, treat, and detect Fusobacteria infections in a subject. In one aspect, vaccines capable of inducing an immune response to a 40 kDa Adhesin protein are used to protect against Fusobacteria infection. Also, nucleic acid molecules, proteins, immunogens, antibodies, and antisense molecules derived from the sequences of the 40 kDa Adhesin protein may be used to protect against, treat, and detect Fusobacteria infections in a subject.