公开(公告)号：US20240093168A1

公开(公告)日：2024-03-21

申请号：US18260452

申请日：2022-01-04

申请人： KAWASAKI GAKUEN EDUCATIONAL FOUNDATION

发明人： Tatsuo ITO ,  Yurika SHIMIZU

IPC分类号： C12N9/22 ,  A61K31/40 ,  A61K31/505 ,  C12N15/10 ,  C12N15/11

CPC分类号： C12N9/22 ,  A61K31/40 ,  A61K31/505 ,  C12N15/10 ,  C12N15/11 ,  C12N2310/20

摘要： The invention provides a CRISPR-dCas/Cas protein derivative or CRISPR-dCas/Cas protein derivative set derived from a CRISPR-dCas (dead Cas) protein or a CRISPR-Cas protein, as well as a polynucleotide encoding the same, a vector comprising the polynucleotide, a transformant transformed by the vector, a carrier for purifying a target RNA, a method for purifying a target RNA, a method for analyzing an intracellular environment, and a prophylactic or therapeutic agent.