公开(公告)号：US10792337B2

公开(公告)日：2020-10-06

申请号：US14206914

申请日：2014-03-12

Applicant: KCI Licensing, Inc.

Inventor： Braden King-Fung Leung ,  Ona Whelove ,  Chester R. Edlund ,  John R. Harper

IPC: A61K38/39 ,  A61L26/00 ,  A61K45/06 ,  A61M1/00 ,  A61M5/142 ,  A61F13/00 ,  A61K33/38 ,  A61K38/01 ,  A61K31/14 ,  A61K33/30 ,  A61K33/34 ,  A61K31/201 ,  A61K36/54 ,  A61K31/155 ,  A61K31/785 ,  A61K33/00 ,  A61K31/7036 ,  A61K35/76 ,  A61K36/61 ,  A61K33/04 ,  A61K36/232 ,  A61K36/886 ,  A61K9/00 ,  A61L15/32 ,  A61K31/085 ,  A61K38/40 ,  A61L15/42 ,  A61L15/46

Abstract: Provided herein are biologically active solution compositions comprising one or more sacrificial proteolytic enzyme substrates, one or more preservatives, and one or more antimicrobial agents and methods of using the solution compositions to treat tissue sites, in particular chronic wounds. The compositions may be used in conjunction with negative pressure wound therapy to treat tissue sites.