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公开(公告)号:US20190275177A1
公开(公告)日:2019-09-12
申请号:US16334160
申请日:2017-11-29
Applicant: KCI Licensing, Inc.
Inventor: Kathleen L. DERRICK , Diwi L. ALLEN , Kristine M. KIESWETTER , Deepak V. KILPADI , Sandra GARCIA-OSBORNE
Abstract: An apparatus and methods for distinguishing outgrowth of cells from surrounding biological material are disclosed. In some embodiments, the method may include delivering a marker to cellular material originating from a donor tissue site, followed by transplanting the cellular material from the donor tissue site to a recipient tissue site. One or more locations of the transplanted cellular material at the recipient site may be identified by locating a distribution of the marker at the recipient tissue site.
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公开(公告)号:US20210161723A1
公开(公告)日:2021-06-03
申请号:US16618844
申请日:2018-06-12
Applicant: KCI Licensing, Inc.
Inventor: Timothy Mark ROBINSON , Christopher Brian LOCKE , Diwi L. ALLEN , James COURAGE
Abstract: A method of manufacturing a tissue interface for a reduced pressure tissue treatment system is provided. The method includes foaming a plurality of polymer particles to form a porous polymer. The method also includes sintering the porous polymer to form a sintered porous polymer. The method further includes texturing the sintered porous polymer. A system to provide reduced pressure at a tissue site is provided. The system includes a cover configured to form a seal over the tissue site. The system also includes a reduced-pressure source configured to provide reduced pressure through the cover at the tissue site. The system further includes a tissue interface configured to be disposed underneath the cover at the tissue site and comprising a porous polymer that is formed from one or more polymer particles that may be foamed and textured.
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3.
公开(公告)号:US20200375805A1
公开(公告)日:2020-12-03
申请号:US16757343
申请日:2018-10-22
Applicant: KCI Licensing, Inc.
Inventor: Timothy Mark ROBINSON , Christopher Brian LOCKE , Benjamin Andrew PRATT , Larry Tab RANDOLPH , Justin Alexander LONG , James COURAGE , Diwi L. ALLEN , Kristine M. KIESWETTER
Abstract: An apparatus for filling a wound can include an array of at least four truncated ellipsoids interconnected to define at least one fluid path through, for example perpendicular to, the array. The longest principal axis of each ellipsoid may be perpendicular to the array. Each truncated ellipsoid may be a spheroid and/or may include an approximately elliptical contact surface at each contact surface between two interconnected ellipsoids. Each fluid pathway may have four continuously-curved concave sides and may have a parallelogram-shaped cross-section with continuously-curved concave edges. A dressing may include the apparatus, a dressing layer coupled to the apparatus, a backing layer disposed over a surface of the dressing layer opposite the apparatus, and an attachment device disposed on at least a margin of the backing layer. Methods of treating various tissue sites using the apparatus or dressing with negative-pressure therapy are also disclosed.
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4.
公开(公告)号:US20210338490A1
公开(公告)日:2021-11-04
申请号:US17285882
申请日:2019-10-04
Applicant: KCI Licensing, Inc.
Inventor: Kristine M. KIESWETTER , Timothy Mark ROBINSON , Diwi L. ALLEN
Abstract: A dressing for treating a tissue site with negative pressure may include a manifold including a first surface and a second surface opposite the first surface, a first layer adjacent to the first surface and a second layer adjacent to the second surface, the first layer and the second layer each comprising a polymer film, a plurality of fluid restrictions in the polymer film adjacent to at least the first surface, and at least one x-ray detectable marker extending in a linear pattern along the dressing.
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公开(公告)号:US20210169701A1
公开(公告)日:2021-06-10
申请号:US16768614
申请日:2018-11-29
Applicant: KCI Licensing, Inc.
Inventor: Diwi L. ALLEN , James COURAGE , Prathamesh KHARKAR
IPC: A61F13/02 , A61L15/32 , A61L15/24 , A61L15/58 , A61B17/322
Abstract: In one aspect, a dressing for transferring skin grafts from a donor site to a recipient site is disclosed, which comprises a substrate having a surface configured for contact with one or more epidermal skin grafts, a plurality of capture sites distributed across said substrate surface, wherein each of said capture sites is configured for capturing at least one epidermal skin graft, and a plurality of topographical features distributed over said substrate surface and coupled to at least one of said capture sites so as to provide at least one of inducing proliferation and facilitating migration of keratinocytes in the captured epidermal skin grafts to surrounding tissue.
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公开(公告)号:US20190240073A1
公开(公告)日:2019-08-08
申请号:US16261291
申请日:2019-01-29
Applicant: KCI Licensing, Inc.
Inventor: Diwi L. ALLEN , Christopher Allen CARROLL , Marisa SCHMIDT , Prathamesh KHARKAR
CPC classification number: A61F13/00068 , A61F13/36 , A61F2013/00536 , A61M1/0088
Abstract: In an example embodiment, a dressing for disrupting debris in a tissue site may comprise a manifold having a first face and a second face. The dressing may also include a plurality of surface features formed from a compressible material. The plurality of surface features may define channels on at least the first face of the manifold. The channels may receive tissue in response to the application of negative pressure. In another example embodiment, a system for softening tissue at a tissue site may include a contact layer. The contact layer may include at least two concentric edges and at least one frangible strut mechanically coupling the concentric edges. The concentric edges and the frangible strut may define through-holes in the contact layer. The through-holes in the contact layer may have an open area in a range of about 0.25 square centimeters to about 15 square centimeters.
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公开(公告)号:US20240156643A1
公开(公告)日:2024-05-16
申请号:US17772956
申请日:2020-11-06
Applicant: KCI Licensing, Inc.
Inventor: Diwi L. ALLEN , Prathamesh Madhav KHARKAR , Marisa SCHMIDT
IPC: A61F13/0246 , A61F13/05
CPC classification number: A61F13/025 , A61F13/0253 , A61F13/05
Abstract: This disclosure describes devices, systems, and methods related to dressings with regions with different adhesive properties, and manufacture and use thereof. An illustrative dressing includes a first region including a first adhesive material. The first adhesive material has a first tackiness. The dressing further includes at least a second region including a second adhesive material. The second adhesive material has a second tackiness in a first phase and a third tackiness in a second phase. The third tackiness is greater than the second tackiness. The first adhesive material is configured to maintain the first tackiness when the second adhesive material in the second phase.
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公开(公告)号:US20220347017A1
公开(公告)日:2022-11-03
申请号:US17861074
申请日:2022-07-08
Applicant: KCI Licensing, Inc.
Inventor: Timothy Mark ROBINSON , Christopher Brian LOCKE , Benjamin Andrew PRATT , Larry Tab RANDOLPH , Justin Alexander LONG , James COURAGE , Diwi L. ALLEN , Kristine M. KIESWETTER
Abstract: An apparatus for filling a wound can include an array of at least four truncated ellipsoids interconnected to define at least one fluid path through, for example perpendicular to, the array. The longest principal axis of each ellipsoid may be perpendicular to the array. Each truncated ellipsoid may be a spheroid and/or may include an approximately elliptical contact surface at each contact surface between two interconnected ellipsoids. Each fluid pathway may have four continuously-curved concave sides and may have a parallelogram-shaped cross-section with continuously-curved concave edges. A dressing may include the apparatus, a dressing layer coupled to the apparatus, a backing layer disposed over a surface of the dressing layer opposite the apparatus, and an attachment device disposed on at least a margin of the backing layer. Methods of treating various tissue sites using the apparatus or dressing with negative-pressure therapy are also disclosed.
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公开(公告)号:US20220354701A1
公开(公告)日:2022-11-10
申请号:US17621157
申请日:2020-05-19
Applicant: KCI Licensing, Inc.
Abstract: Dressings for treating a tissue site with negative pressure are disclosed, which may include a dressing having multiple layers and incorporating a material adapted to neutralize proteolytic enzymes. In one example embodiment, a dressing may include a first layer comprising a hydrophobic gel having a plurality of apertures. A material adapted to neutralize proteolytic enzymes may be applied to a surface of the first layer. The dressing may further include a second layer comprising a fenestrated film and coupled to the first layer. Additionally, the dressing may include a third layer comprising a manifold, which in some instances may be a polymeric foam. The dressing may further include a fourth layer comprising a polymer drape.
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公开(公告)号:US20220202620A1
公开(公告)日:2022-06-30
申请号:US17605168
申请日:2020-03-20
Applicant: KCI Licensing, Inc.
Inventor: Diwi L. ALLEN , Prathamesh Madhav KHARKAR
IPC: A61F13/00 , A61M1/00 , A61M35/00 , A61K38/39 , A61K31/727 , A61K31/737
Abstract: A system for use in treating a tissue site with negative pressure, which may comprise a dressing or tissue interface and a plurality of standoffs for storing and releasing a biocompatible polymer to the tissue site. The standoff may be cells or closed-end cells. In some examples, the biocompatible polymer may comprise collagen, oxidized regenerated cellulose, or a combination thereof. Method for using and manufacturing the dressing or tissue interface may also be disclosed.
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