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公开(公告)号：US20230134190A1
公开(公告)日：2023-05-04
申请号：US17951231
申请日：2022-09-23
IPC分类号： A61F9/008
摘要： The present invention relates to an apparatus for cutting-out including a device for treating a L.A.S.E.R. beam generated by a femtosecond laser (1), and positioned downstream from said femtosecond laser, the treatment device comprising: a shaping system (3) positioned on the trajectory of said beam, for modulating the phase of the wave front of the L.A.S.E.R. beam according to a modulation set value calculated for distributing the energy of the L.A.S.E.R. beam in at least two impact points forming a pattern in its focal plane, an optical focusing system (5) downstream from the shaping system, the optical focusing system comprising a concentrator module for focusing the phase-modulated L.A.S.E.R. beam in a focusing plane and a depth-positioning module for displacing the focusing plane into a plurality of cutting-out planes, a sweeping optical scanner (4) positioned between the concentrator module and the depth-positioning module for displacing the pattern in the cutting-out plane in a plurality of positions.
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公开(公告)号：US20220104970A1
公开(公告)日：2022-04-07
申请号：US17554049
申请日：2021-12-17
IPC分类号： A61F9/008
摘要： The present invention relates to apparatus for cutting out a human or animal tissue, such as a cornea, or a lens, said apparatus including a treatment device for producing a pattern consisting of at least two impact points in a focusing plane from a L.A.S.E.R. beam generated by a femtosecond laser (1), the treatment device being positioned downstream from said femtosecond laser, remarkable in that the treatment device comprises an optical focusing system (5) for focusing the L.A.S.E.R. beam in a cutting-out plane, and a control unit (6) able to control the displacement of the optical focusing system along an optical path of the L.A.S.E.R. beam for displacing the focusing plane in at least three respective cutting-out planes so as to form a stack of surfaces for cutting out the tissue.
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公开(公告)号：US20220257418A1
公开(公告)日：2022-08-18
申请号：US17735417
申请日：2022-05-03
发明人： Aurelien BERNARD , Philippe GAIN , Cyril MAUCLAIR , Gilles THURET
IPC分类号： A61F9/008 , B23K26/067 , B23K26/38 , A61F9/009 , A61F9/013
摘要： A device for cutting human or animal tissue including a femtosecond laser that can emit a L.A.S.E.R. beam in the form of impulses. The device directs and focuses the beam onto or into the tissue for the cutting thereof. The device further includes and element to shape the L.A.S.E.R. beam, positioned in the trajectory of the beam, and to modulate the energy distribution of the L.A.S.E.R. beam in the focal plane thereof, corresponding to the cutting plane.
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公开(公告)号：US20170304118A1
公开(公告)日：2017-10-26
申请号：US15517480
申请日：2015-10-07
发明人： Aurelien BERNARD , Philippe GAIN , Cyril MAUCLAIR , Gilles THURET
CPC分类号： A61F9/00804 , A61F9/00825 , A61F9/009 , A61F9/013 , A61F2009/0087 , A61F2009/00872 , A61F2009/00887 , A61F2009/00889 , A61F2009/00895 , B23K26/0676 , B23K26/38 , B23K2103/32
摘要： The invention relates to a device (1) for cutting human or animal tissue, such as a cornea (3), or a crystalline lens, said device comprising a femtosecond laser (2) that can emit a L.A.S.E.R. beam (4) in the form of impulses, and means for directing and focusing said beam onto or into the tissue for the cutting thereof as such. According to the invention, the device comprises means (9) for shaping the L.A.S.E.R. beam (4), which are positioned in the trajectory of said beam, and can modulate the energy distribution of the L.A.S.E.R. beam (4) in the focal plane thereof, corresponding to the cutting plane.
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5.发明申请公开(公告)号：US20220249222A1
公开(公告)日：2022-08-11
申请号：US17629253
申请日：2020-07-22
申请人： UNIVERSITE JEAN MONNET SAINT ETIENNE , MANUTECH-USD , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , CENTRE HOSPITALIER UNIVERSITAIRE
发明人： Philippe GAIN , Gilles THURET , Cyril MAUCLAIR , Samy ALBOURGOL , Gregory EGAUD
摘要： The invention concerns a cutting process for producing a plurality of implants from a previously removed human or animal cornea, wherein the process comprises the following steps: depositing (200) the cornea in a holding device, cutting (300), using a laser source, the cornea contained in the holding device to obtain a cut cornea, detaching (400) each implant from the cut cornea, decellularizing (500) each detached implant to obtain decellularized implants, lyophilizing (600) each decellularized implant to obtain lyophilized implants, sterilizing (700) each lyophilized implant to obtain sterilized implants, packaging (800) each sterilized implant to obtain packaged implants.
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公开(公告)号：US20210321607A1
公开(公告)日：2021-10-21
申请号：US17261107
申请日：2019-07-17
申请人： UNIVERSITÉ JEAN MONNET SAINT ETIENNE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , CENTRE HOSPITALIER UNIVERSITAIRE , MANUTECH-USD
摘要： The present invention relates to a device for holding human or animal corneal tissue previously removed for photon treatment thereof with electromagnetic radiation, notable in that the holding device comprises: a stack of elements along a longitudinal axis (A-A′) of the device, said stack comprising: a first plate (1) that is transparent to the electromagnetic radiation, a peripheral seal (4) positioned on the first plate (1), the peripheral seal (4) being intended to extend around the corneal tissue (6), a second plate (2) that is transparent to the electromagnetic radiation on the peripheral seal (4), an immobilizing system (51, 52) for immobilizing the stack of elements and able to press the first and second plates (1, 2) firmly against the corneal tissue in order to apply mechanical stress to the anterior and posterior faces of the corneal tissue.
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公开(公告)号：US20190159933A1
公开(公告)日：2019-05-30
申请号：US16091711
申请日：2017-04-06
申请人： KERANOVA
IPC分类号： A61F9/008
摘要： The present invention relates to apparatus for cutting out a human or animal tissue, such as a cornea, or a lens, said apparatus including a treatment device for producing a pattern consisting of at least two impact points in a focusing plane from a L.A.S.E.R. beam generated by a femtosecond laser (1), the treatment device being positioned downstream from said femtosecond laser, remarkable in that the treatment device comprises an optical focusing system (5) for focusing the L.A.S.E.R. beam in a cutting-out plane, and a control unit (6) able to control the displacement of the optical focusing system along an optical path of the L.A.S.E.R. beam for displacing the focusing plane in at least three respective cutting-out planes so as to form a stack of surfaces for cutting out the tissue.
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公开(公告)号：US20230404806A1
公开(公告)日：2023-12-21
申请号：US18251197
申请日：2021-10-28
申请人： KERANOVA
IPC分类号： A61F9/008
CPC分类号： A61F9/0084 , A61F2009/0087 , A61F2009/00872 , A61F2009/00897
摘要： The invention relates to a cutting apparatus including a femtosecond laser source (10) for emitting a Gaussian laser beam, a shaping system (30) including a spatial modulator of light for modulating the Gaussian laser beam, a sweeping optical scanner (40) for moving the modulated laser beam, an optical focusing system (50) for focusing the modulated laser beam, characterised in that the processing device further comprises a control unit (60) for controlling the femtosecond laser source (10), the shaping system (30), the sweeping optical scanner (40) and the optical focusing system (50), in order to produce: —at least one vertical cutting plane, and —at least one horizontal cutting plane; the spatial light modulator of the shaping system (30) being capable of emulating an axicon for generating a Bessel beam.
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公开(公告)号：US20200030145A1
公开(公告)日：2020-01-30
申请号：US16091881
申请日：2017-04-06
申请人： KERANOVA
IPC分类号： A61F9/008
摘要： The present invention relates to an apparatus for cutting-out including a device for treating a L.A.S.E.R. beam generated by a femtosecond laser (1), and positioned downstream from said femtosecond laser, the treatment device comprising: a shaping system (3) positioned on the trajectory of said beam, for modulating the phase of the wave front of the L.A.S.E.R. beam according to a modulation set value calculated for distributing the energy of the L.A.S.E.R. beam in at least two impact points forming a pattern in its focal plane, an optical focusing system (5) downstream from the shaping system, the optical focusing system comprising a concentrator module for focusing the phase-modulated L.A.S.E.R. beam in a focusing plane and a depth-positioning module for displacing the focusing plane into a plurality of cutting-out planes, a sweeping optical scanner (4) positioned between the concentrator module and the depth-positioning module for displacing the pattern in the cutting-out plane in a plurality of positions.
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