公开(公告)号：US12084533B1

公开(公告)日：2024-09-10

申请号：US18581246

申请日：2024-02-19

Applicant: KING FAISAL UNIVERSITY

Inventor： Saad Shaaban ,  Manal Amin Hessien ,  Amr Negm ,  Tarek A. Yousef

IPC: C08F289/00 ,  B01D67/00 ,  B01D71/10 ,  B01D71/82 ,  C02F1/44 ,  C02F101/30 ,  C08H8/00 ,  C08J5/18

CPC classification number: C08F289/00 ,  B01D67/0011 ,  B01D67/0013 ,  B01D71/10 ,  B01D71/82 ,  C02F1/44 ,  C08H8/00 ,  C08J5/18 ,  B01D2323/08 ,  B01D2323/42 ,  C02F2101/301 ,  C08J2351/08

Abstract: A method of making a lignocellulose incorporating methacrylate functionality from date palm biomass can include extracting sieved date palm biomass at a first predetermined temperature (110° C.) to obtain an extracted date palm biomass; adding an acid to the extracted date palm biomass to obtain a mixture and stirring and refluxing the mixture at a second predetermined temperature (100° C.) to obtain a refluxed cellulose-hemicellulose-lignin residue; dissolving the refluxed cellulose-hemicellulose-lignin residue in a solvent to obtain a solution; adding triethylamine and methacrylic anhydride to the solution to obtain a reaction solution mixture and stirring while heating the reaction solution mixture to react the triethylamine and the methacrylic anhydride with the solution to obtain a reacted solution mixture; pouring the reacted solution mixture into an ice-cold solvent to obtain a solution mixture and separating cellulose-hemicellulose-lignin residue from the solution mixture via centrifuging; dissolving centrifuged cellulose-lignin residue in water to obtain the lignocellulose incorporating methacrylate functionality.

公开(公告)号：US11970464B1

公开(公告)日：2024-04-30

申请号：US18386198

申请日：2023-11-01

Applicant: KING FAISAL UNIVERSITY

Inventor： Saad Shaaban ,  Hany Mohamed Abd El-Lateef Ahmed ,  Bander Alshemary

IPC: A61K31/517 ,  C07D239/74 ,  C07D471/04 ,  C07D471/14

CPC classification number: C07D239/74 ,  C07D471/04 ,  C07D471/14

Abstract: Multitarget-directed compounds combining the features of reactive oxygen species (ROS) modulators, poly (ADP-ribose) polymerase 1 (PARP1), and/or heat shock protein 90 (Hsp90) inhibitors in a single molecule. These single agents constitute a systemic regimen for treating the triple-negative breast cancer phenotype that overcomes drug resistance and tumor recurrence, and may be used for other indications as well, such as the treatment of various neurodegenerative disorders.

公开(公告)号：US11920060B1

公开(公告)日：2024-03-05

申请号：US18236016

申请日：2023-08-21

Applicant: KING FAISAL UNIVERSITY

Inventor： Saad Shaaban ,  Amr Negm ,  Hany Mohamed Abd El-Lateef Ahmed ,  Tarek Ahmed Yousef ,  Ahmed S. M. Aljanabi

IPC: C09D5/08 ,  C07C391/02 ,  C09D101/02

CPC classification number: C09D5/086 ,  C07C391/02 ,  C09D101/02

Abstract: New diorganyl diselenide compounds are described herein, as well as the use of such diorganyl diselenide compounds in forming anticorrosion coatings for stainless steel. Also described are methods for forming the new diorganyl diselenide compounds as well as anti-corrosion coatings containing the diorganyl diselenide compounds.

公开(公告)号：US11891363B1

公开(公告)日：2024-02-06

申请号：US18217084

申请日：2023-06-30

Applicant: KING FAISAL UNIVERSITY

Inventor： Saad Shaaban ,  Hany Mohamed Abd El-Lateef Ahmed ,  Bander Alshemary

IPC: C07D239/72 ,  A61K31/517 ,  C07D239/74 ,  C07D471/14 ,  C07D471/04

CPC classification number: C07D239/74 ,  C07D471/04 ,  C07D471/14

Abstract: Multitarget-directed compounds combining the features of reactive oxygen species (ROS) modulators, poly (ADP-ribose) polymerase 1 (PARP1), and/or heat shock protein 90 (Hsp90) inhibitors in a single molecule. These single agents constitute a systemic regimen for treating the triple-negative breast cancer phenotype that overcomes drug resistance and tumor recurrence, and may be used for other indications as well, such as the treatment of various neurodegenerative disorders.

公开(公告)号：US12168758B1

公开(公告)日：2024-12-17

申请号：US18435643

申请日：2024-02-07

Applicant: KING FAISAL UNIVERSITY

Inventor： Saad Shaaban ,  Ali Aqeel ,  Yasair Al-Faiyz ,  Hussein Ba-Ghazal ,  Ahmed A. Al-Karmalawy

IPC: C11C3/10 ,  B01J31/16 ,  B01J37/03 ,  B01J37/04 ,  B01J37/06 ,  B01J37/08 ,  C07F3/06 ,  C10L1/18

Abstract: A zinc coordination organoselenium polymer may be a catalyst. The zinc coordination polymer may be a catalyst for biodiesel fuel. A method of forming biodiesel from waster oil may include using the zinc coordination polymer. The waste oil may be selected from a group consisting of vegetable oil and animal fats.

公开(公告)号：US11964947B1

公开(公告)日：2024-04-23

申请号：US18386231

申请日：2023-11-01

Applicant: KING FAISAL UNIVERSITY

Inventor： Saad Shaaban ,  Hany Mohamed Abd El-Lateef Ahmed ,  Bander Alshemary

IPC: C07D487/14 ,  A61K31/506 ,  C07D239/74 ,  C07D471/04 ,  C07D471/14

CPC classification number: C07D239/74 ,  C07D471/04 ,  C07D471/14

Abstract: Multitarget-directed compounds combining the features of reactive oxygen species (ROS) modulators, poly (ADP-ribose) polymerase 1 (PARP1), and/or heat shock protein 90 (Hsp90) inhibitors in a single molecule. These single agents constitute a systemic regimen for treating the triple-negative breast cancer phenotype that overcomes drug resistance and tumor recurrence, and may be used for other indications as well, such as the treatment of various neurodegenerative disorders.

公开(公告)号：US11845750B1

公开(公告)日：2023-12-19

申请号：US18231103

申请日：2023-08-07

Applicant: KING FAISAL UNIVERSITY

Inventor： Amr Negm ,  Saad Shaaban ,  Yasair S. Al-Faiz

IPC: C07D475/04 ,  C12N9/06

CPC classification number: C07D475/04 ,  C12N9/0028 ,  C12Y105/01005 ,  C12Y105/01015

Abstract: Novel organoselenium compounds formed with folates that can be used to maximize anticancer activity of the organoselenium. Novel organoselenium compounds that can be used as a chemopreventive against cancer. These compounds may be present in pharmaceutical compositions and may be used in various treatment methods.

公开(公告)号：US12084359B1

公开(公告)日：2024-09-10

申请号：US18403431

申请日：2024-01-03

Applicant: KING FAISAL UNIVERSITY

Inventor： Saad Shaaban ,  Hany Mohamed Abd El-Lateef Ahmed ,  Kamal Shalabi

IPC: C02F1/28 ,  C08L97/02 ,  C02F101/20 ,  C02F101/30

CPC classification number: C02F1/286 ,  C08L97/02 ,  C02F2101/20 ,  C02F2101/30

Abstract: Lignocellulose based hydrogels (LCHs) derived from date palm (DP) waste that can be used to overcome water treatment challenges, as well as a preparation method and application thereof.

公开(公告)号：US12060359B1

公开(公告)日：2024-08-13

申请号：US18412741

申请日：2024-01-15

Applicant: KING FAISAL UNIVERSITY

Inventor： Saad Shaaban ,  Ali Khalid Al-Hajji ,  Yasair Al-Faiyz ,  Amr Negm

IPC: C07D487/04 ,  A61K31/519

CPC classification number: C07D487/04 ,  A61K31/519

Abstract: Synthesis and characterization of organoselenium-based triazolo pyrimidines and their use in treating hypoxia and inhibiting prolyl-hydroxylase domain (PHD) activity. The organoselenium-based triazolo pyrimidines have the formula:






wherein R is selected from the group consisting of —SeCH3, —SePhenyl, —CH2SeCH3, and —CH2SePhenyl.

公开(公告)号：US12006293B1

公开(公告)日：2024-06-11

申请号：US18545056

申请日：2023-12-19

Applicant: KING FAISAL UNIVERSITY

Inventor： Saad Shaaban ,  Amr Negm

IPC: C07D231/12 ,  A61K31/4155 ,  A61K31/4375 ,  C07D213/65 ,  C07D401/14

CPC classification number: C07D231/12 ,  A61K31/4155 ,  A61K31/4375 ,  C07D213/65 ,  C07D401/14

Abstract: Diselenide organo compounds, their synthesis, and their use as deubiquitination signaling pathway modulators and anti-cancer agents.