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    ILLUMINATION DEVICES FOR INDUCING BIOLOGICAL EFFECTS
    1.
    发明申请
    ILLUMINATION DEVICES FOR INDUCING BIOLOGICAL EFFECTS 有权

    公开(公告)号：US20210290970A1

    公开(公告)日：2021-09-23

    申请号：US17162259

    申请日：2021-01-29

    申请人： KNOW Bio, LLC

    发明人： F. Neal Hunter ,  Antony Paul van de Ven ,  Nathan Stasko ,  David T. Emerson ,  Michael John Bergmann ,  Thomas Matthew Womble ,  Adam Cockrell ,  Rebecca McDonald

    IPC分类号： A61N5/06 ,  G16H40/67 ,  G16H20/40

    摘要： Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and tissues with increased efficacy and reduced cytotoxicity. Illumination devices may be configured to communicate with networks and/or servers to provide control and/or management of phototherapy treatments.

    PHOTOTHERAPEUTIC LIGHT FOR TREATMENT OF PATHOGENS
    2.
    发明申请
    PHOTOTHERAPEUTIC LIGHT FOR TREATMENT OF PATHOGENS 有权

    公开(公告)号：US20210138259A1

    公开(公告)日：2021-05-13

    申请号：US17148090

    申请日：2021-01-13

    申请人： KNOW Bio, LLC

    发明人： Nathan Stasko ,  David T. Emerson ,  Adam Cockrell ,  F. Neal Hunter ,  Michael John Bergmann ,  Rebecca McDonald ,  Nicholas William Medendorp, JR. ,  Gerald H. Negley ,  Katelyn P. Reighard

    IPC分类号： A61N5/06 ,  H01L27/15

    摘要： Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity.

    Illumination devices for inducing biological effects
    4.
    发明授权
    Illumination devices for inducing biological effects 有权

    公开(公告)号：US11752359B2

    公开(公告)日：2023-09-12

    申请号：US17410154

    申请日：2021-08-24

    申请人： KNOW Bio, LLC

    发明人： David T. Emerson ,  Michael John Bergmann ,  Thomas Matthew Womble ,  Antony Paul van de Ven ,  Nathan Stasko ,  F. Neal Hunter ,  Adam Cockrell ,  Rebecca McDonald ,  James Michael Lay

    IPC分类号： A61N5/06

    CPC分类号： A61N5/0624 ,  A61N2005/0606 ,  A61N2005/0632 ,  A61N2005/0644 ,  A61N2005/0662

    摘要： Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and tissues with increased efficacy and reduced cytotoxicity. Particular illumination devices are disclosed that provide safe and effective treatments for upper respiratory tract infections, including coronaviridae and orthomyxoviridae.

    PHOTOTHERAPEUTIC LIGHT FOR TREATMENT OF PATHOGENS
    5.
    发明申请
    PHOTOTHERAPEUTIC LIGHT FOR TREATMENT OF PATHOGENS 有权

    公开(公告)号：US20210128938A1

    公开(公告)日：2021-05-06

    申请号：US17148133

    申请日：2021-01-13

    申请人： KNOW Bio, LLC

    发明人： Nathan Stasko ,  David T. Emerson ,  Adam Cockrell ,  F. Neal Hunter ,  Michael John Bergmann ,  Rebecca McDonald ,  Nicholas William Medendorp, JR. ,  Gerald H. Negley ,  Katelyn P. Reighard

    IPC分类号： A61N5/06 ,  H01L27/15

    摘要： Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity.

    PHOTOTHERAPEUTIC LIGHT FOR TREATMENT OF PATHOGENS
    6.
    发明申请
    PHOTOTHERAPEUTIC LIGHT FOR TREATMENT OF PATHOGENS 有权

    公开(公告)号：US20210128936A1

    公开(公告)日：2021-05-06

    申请号：US17148108

    申请日：2021-01-13

    申请人： KNOW Bio, LLC

    发明人： Nathan Stasko ,  David T. Emerson ,  Adam Cockrell ,  F. Neal Hunter ,  Michael John Bergmann ,  Rebecca McDonald ,  Nicholas William Medendorp, JR. ,  Gerald H. Negley ,  Katelyn P. Reighard

    IPC分类号： A61N5/06 ,  H01L27/15

    摘要： Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity.

    ILLUMINATION DEVICES FOR INDUCING BIOLOGICAL EFFECTS
    7.
    发明公开
    ILLUMINATION DEVICES FOR INDUCING BIOLOGICAL EFFECTS 审中-公开

    公开(公告)号：US20240293681A1

    公开(公告)日：2024-09-05

    申请号：US18659119

    申请日：2024-05-09

    申请人： KNOW Bio, LLC

    发明人： F. Neal Hunter ,  Antony Paul van de Ven ,  Nathan Stasko ,  David T. Emerson ,  Michael John Bergmann ,  Thomas Matthew Womble ,  Adam Cockrell ,  Rebecca McDonald

    IPC分类号： A61N5/06

    CPC分类号： A61N5/0624 ,  A61N5/0603 ,  A61N2005/0606 ,  A61N2005/0662

    摘要： Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and tissues with increased efficacy and reduced cytotoxicity. Illumination devices may be configured to communicate with networks and/or servers to provide control and/or management of phototherapy treatments.

    ILLUMINATION DEVICES FOR INDUCING BIOLOGICAL EFFECTS
    10.
    发明公开
    ILLUMINATION DEVICES FOR INDUCING BIOLOGICAL EFFECTS 审中-公开

    公开(公告)号：US20230302293A1

    公开(公告)日：2023-09-28

    申请号：US18322257

    申请日：2023-05-23

    申请人： KNOW Bio, LLC

    发明人： David T. Emerson ,  Michael John Bergmann ,  Thomas Matthew Womble ,  Antony Paul van de Ven ,  Nathan Stasko ,  F. Neal Hunter ,  Adam Cockrell ,  Rebecca McDonald ,  James Michael Lay

    IPC分类号： A61N5/06

    CPC分类号： A61N5/0624 ,  A61N2005/0606 ,  A61N2005/0632 ,  A61N2005/0644 ,  A61N2005/0662

    摘要： Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an antiinflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and tissues with increased efficacy and reduced cytotoxicity. Particular illumination devices are disclosed that provide safe and effective treatments for upper respiratory tract infections, including coronaviridae and orthomyxoviridae.