公开(公告)号：US20230288514A1

公开(公告)日：2023-09-14

申请号：US18013922

申请日：2021-07-01

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Thomas Erik Amthor ,  Mariya Ivanova Doneva ,  Peter Koken ,  Kay Nehrke

IPC: G01R33/56 ,  G01R33/48

CPC classification number: G01R33/5608 ,  G01R33/4828

Abstract: Disclosed herein is a medical system (100, 300) comprising a memory (110) storing machine executable instructions (120) and an MRF scoring module (122). The MRF scoring module is configured for outputting an MRF quality score (126) in response to receiving MRF data (124) as input. The medical system further comprises a computational system (106) configured for controlling the medical system, wherein execution of the machine executable instructions causes the computational system to: receive (200) the MRF data; receive (202) the MRF quality score in response to inputting the MRF data into an MRF scoring module; append (206) the MRF quality score to the MRF data if the MRF quality score is within a predetermined range (128); and provide (208) a signal (132) if the MRF quality score is outside of the predetermined range.

公开(公告)号：US10088543B2

公开(公告)日：2018-10-02

申请号：US14774314

申请日：2014-03-11

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Peter Bornert ,  Mariya Ivanova Doneva ,  Kay Nehrke

IPC: G01V3/00 ,  G01R33/561 ,  G01R33/36 ,  G01R33/385 ,  G01R33/483

Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). The method comprises the steps of: —subjecting the object (10) to an imaging sequence comprising phase-modulated multi-slice RF pulses for simultaneously exciting two or more spatially separate image slices, —acquiring MR signals, wherein the MR signals are received in parallel via a set of at least two RF coils (11, 12, 13) having different spatial sensitivity profiles within the examination volume, and —reconstructing a MR image for each image slice from the acquired MR signals, wherein MR signal contributions from the different image slices are separated on the basis of the spatial sensitivity profiles of the at least two RF coils (11, 12, 13) and on the basis of the phase modulation scheme of the RF pulses. In order to optimize the conditioning of the inverse problem of the MR image reconstruction, the phase-modulation scheme of the RF pulses is derived from the spatial sensitivity profiles of the at least two RF coils (11, 12, 13). Moreover, the invention relates to a MR device for carrying out this method as well as to a computer program to be run on a MR device.

公开(公告)号：US20230122915A1

公开(公告)日：2023-04-20

申请号：US17914435

申请日：2021-03-24

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Kay Nehrke ,  Peter Boernert

IPC: G01R33/565 ,  G01R33/48 ,  G01R33/56 ,  G06N3/08

Abstract: Abstract: Disclosed herein is a medical system comprising a memory (110) storing machine executable instructions (120) and a trained neural network (122). The trained neural network is configured to output corrected magnetic resonance image data (130) in response to receiving as input a set of magnetic resonance images (126) each having a different spatially constant frequency off-resonance factor. The medical system further comprises a computational system (106) configured for controlling the medical system, wherein execution of the machine executable instructions causes the computational system to: receive (200) k-space data (124) acquired according to a magnetic resonance imaging protocol; reconstruct (202) a set of magnetic resonance images (126) according to the magnetic resonance imaging protocol, wherein each of the set of magnetic resonance images is reconstructed assuming a different spatially constant frequency off-resonance factor chosen from a list of frequency off-resonance factors (128); and receive (204) the corrected magnetic resonance image data in response to inputting the set of magnetic resonance images into the trained neural network.

公开(公告)号：US10830856B2

公开(公告)日：2020-11-10

申请号：US16340492

申请日：2017-09-28

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Peter Boernert ,  Miha Fuderer ,  Kay Nehrke ,  Klaas Pruessmann ,  Jurgen Edwin Rahmer ,  Bertram Wilm ,  Christian Stehning

IPC: G01V3/00 ,  G01R33/565 ,  G01R33/385 ,  G01R33/561 ,  G01R33/24

Abstract: A magnetic resonance imaging system includes a gradient system and a processor for controlling the magnetic resonance imaging system. Execution of machine executable instructions causes the magnetic resonance imaging system to: acquire by coil elements first magnetic resonance data simultaneously from a group of passive local probes, wherein the first group of passive local probes includes a plurality of passive local probes located spaced apart from each other; disentangle contributions to the first magnetic resonance data from the individual local probes, calculate for the magnetic resonance imaging system a gradient impulse response function of the gradient system using the first magnetic resonance data from the local probes; and determine correction factors using the gradient impulse response function

公开(公告)号：US10018690B2

公开(公告)日：2018-07-10

申请号：US14652836

申请日：2013-12-11

Applicant: KONINKLIJKE PHILIPS N.V. ,  PHILIPS DEUTSCHLAND GMBH

Inventor： Johannes Adrianus Overweg ,  Kay Nehrke

IPC: G01V3/00 ,  G01R33/28 ,  G01R33/44 ,  G01R33/24 ,  G01R33/385 ,  G01R33/34 ,  G01R33/58

CPC classification number: G01R33/243 ,  G01R33/34 ,  G01R33/385 ,  G01R33/58

Abstract: The present invention provides a phantom (200) for use in a magnetic resonance (MR) imaging system (110) with a set of resonating volumes (206) positioned in a base body (202), whereby the base body (202) has a spherical or ellipsoid shape in accordance with a volume of interest (203) of the MR imaging system (110), and the resonating volumes (206) are located at a circumference of the base body (202). The phantom is used in a method for evaluating the magnetic field of a main magnet (114) of a magnetic resonance (MR) imaging system (110), comprising the steps of positioning the phantom (200) within the main magnet (114), performing a 3D spectroscopic MR measurement of the phantom (200) using the MR imaging system (110), thereby measuring resonances of the resonating volumes (206), assigning the measured resonances to the resonating volumes (206), and evaluating the magnetic field of the main magnet (114) from the MR measurement of the phantom (200) based on the measured resonances of the resonating volumes (206). Accordingly, the MR imaging system itself is directly used for determining the magnetic field of its main magnet. Accordingly, the MR imaging system itself can be used as measurement equipment, instead of a separate NMR magnetometer, which is required for conventional determination of the magnetic field.

公开(公告)号：US09977108B2

公开(公告)日：2018-05-22

申请号：US14432931

申请日：2013-09-11

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Kay Nehrke ,  Peter Boernert ,  Johan Michiel Den Harder ,  Thomas Hendrik Rozijn

IPC: G01R33/20 ,  G01R33/561 ,  G01R33/24 ,  A61B5/055 ,  G01R33/34 ,  G01R33/36 ,  G01R33/385

CPC classification number: G01R33/5611 ,  A61B5/055 ,  G01R33/246 ,  G01R33/34 ,  G01R33/36 ,  G01R33/385

Abstract: The invention relates to a method of parallel MR imaging, wherein a reference scan is performed by means of a stimulated echo sequence including i) at least two preparation RF pulses (α) radiated toward a portion of a body (10) during a preparation period (21), and ii) one or more reading RF pulses (β) radiated toward the portion of the body (10) during an acquisition period (22) temporally subsequent to the preparation period (21). One or more FID signals (I1) and one or more stimulated echo signals (I2) are acquired during the acquisition period (22). The spatial receive and/or—if applicable—transmit4 sensitivity profiles of at least two RF coils (11, 12, 13) are derived from the acquired FID signals (I1) and/or from the acquired stimulated echo signals (I2). The parameters of the stimulated echo sequence are selected such that it is robust against susceptibility-induced artifacts. Moreover, 10 the invention relates to a MR device (1) and to a computer program for a MR device (1).

公开(公告)号：US10222437B2

公开(公告)日：2019-03-05

申请号：US15030430

申请日：2014-10-14

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Kay Nehrke ,  Peter Bornert

IPC: G01R33/48 ,  A61B5/055 ,  G01R33/561

Abstract: The invention relates to a method of MR imaging of an object (10) placed in the examination volume of a MR device (1). It is the object of the invention to provide an improved MR-based temperature mapping method. The method of the invention comprises the steps of: subjecting the object (10) to an imaging sequence of RF pulses and switched magnetic field gradients, which imaging sequence is a stimulated echo sequence including: a) at least two preparation RF pulses (a) radiated toward the object (10) during a preparation period (21), and b) one or more reading RF pulses (β) radiated toward the object (10) during an acquisition period (22) temporally subsequent to the preparation period (21); acquiring at least two MR signals during the acquisition period (22), wherein the two MR signals are either (i) a FID signal (I1, FID) and a stimulated echo signal (I2) or (ii) two stimulated echo signals (STE, STE*); and deriving a temperature map indicating the spatial distribution of the temperature within the object (10) from the at least two acquired MR signals. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

公开(公告)号：US12196832B2

公开(公告)日：2025-01-14

申请号：US18013922

申请日：2021-07-01

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Thomas Erik Amthor ,  Mariya Ivanova Doneva ,  Peter Koken ,  Kay Nehrke

IPC: G01R33/56 ,  G01R33/48

Abstract: Disclosed herein is a medical system (100, 300) comprising a memory (110) storing machine executable instructions (120) and an MRF scoring module (122). The MRF scoring module is configured for outputting an MRF quality score (126) in response to receiving MRF data (124) as input. The medical system further comprises a computational system (106) configured for controlling the medical system, wherein execution of the machine executable instructions causes the computational system to: receive (200) the MRF data; receive (202) the MRF quality score in response to inputting the MRF data into an MRF scoring module; append (206) the MRF quality score to the MRF data if the MRF quality score is within a predetermined range (128); and provide (208) a signal (132) if the MRF quality score is outside of the predetermined range.

公开(公告)号：US11906607B2

公开(公告)日：2024-02-20

申请号：US17609527

申请日：2020-05-06

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Holger Eggers ,  Kay Nehrke ,  Peter Boernert

IPC: G01V3/00 ,  G01R33/48 ,  G01R33/54

CPC classification number: G01R33/4826 ,  G01R33/4816 ,  G01R33/543

Abstract: The invention relates to a method of MR imaging of an object positioned in an examination volume of a MR device (1). It is an object of the invention to enable efficient silent ZTE imaging with self-refocusing. The method of the invention comprises the steps of:—specification of a set of radial k-space spokes to cover a spherical k-space volume;—selection of subsets of a predetermined number of spokes from the specified set so that the concatenation of the spokes contained in each of the subsets forms a closed trajectory in k-space, wherein the selection of the subsets involves optimizing a cost function;—subjecting the object (10) to a zero echo time imaging sequence, wherein each of the subsets of spokes is acquired as a sequence of gradient echo signals; and—reconstructing an MR image from the acquired spokes. Moreover, the invention relates to a MR device and to a computer program for a MR device.

公开(公告)号：US20230145981A1

公开(公告)日：2023-05-11

申请号：US17918582

申请日：2021-04-20

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Kay Nehrke ,  Peter Boernert

IPC: G01R33/24 ,  G01R33/56 ,  G01R33/50 ,  G01R33/561

CPC classification number: G01R33/246 ,  G01R33/5602 ,  G01R33/50 ,  G01R33/5617

Abstract: The invention relates to a method of MR imaging. It is an object of the invention to provide an improved B1 mapping method that is less affected by T1 relaxation. The invention proposes that a first stimulated echo imaging sequence (25) is generated comprising at least two preparation RF pulses (α) radiated during a first preparation period (21) and a sequence of reading RF pulses (β) radiated during a first acquisition period (22) temporally subsequent to the first preparation period (21). A first set of FID signals (IFID) and a first set of stimulated echo signals (ISTE) are acquired during the first acquisition period (22). A second stimulated echo imaging sequence (27) is generated comprising again at least two preparation RF pulses (α) radiated during a second preparation period (21) and a sequence of reading RF pulses (β) radiated during a second acquisition period (22) temporally subsequent to the second preparation period (21). A second set of FID signals (IFID) and a second set of stimulated echo signals (ISTE) are acquired during the second acquisition period (22). The first and second sets of FID signals (IFID) have different T1-weightings and/or the first and second sets of stimulated echo signals (ISTE) have different T1-weightings. A B1 map indicating the spatial distribution of the RF field of the RF pulses is derived from the acquired first and second sets of FID (IFID) and stimulated echo (ISTE) signals, wherein the different T1-weightings are made use of to compensate for influences on the B1 map caused by T1 relaxation. Preferably, either the first or the second preparation period (21) is preceded by an RF inversion pulse to obtain the different T1-weightings. Moreover, the invention relates to an MR device (1) and to a computer program for an MR device (1).