公开(公告)号：US10816625B2

公开(公告)日：2020-10-27

申请号：US16095954

申请日：2017-04-26

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Peter Bornert ,  Kay Nehrke ,  Mariya Ivanova Doneva ,  Thomas Erik Amthor ,  Peter Koken ,  George Randall Duensing

IPC: G01R33/50 ,  G01R33/48 ,  G01R33/56 ,  G01R33/561 ,  G01R33/563 ,  G01R33/485

Abstract: The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within an imaging zone (108). The magnetic resonance imaging system comprises a memory (134, 136) for storing machine executable instructions (160), and pulse sequence commands (140, 400, 502, 600, 700), wherein the pulse sequence commands are configured to cause the magnetic imaging resonance system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting technique. The pulse sequence commands are further configured to control the magnetic resonance imaging system to perform spatial encoding using a zero echo time magnetic resonance imaging protocol. Execution of the machine executable instructions causes the processor controlling the MRI system to: acquire (200) the magnetic resonance data by controlling the magnetic resonance imaging system with the pulse sequence commands; and calculate (202) a spatial distribution (146) of each of a set of predetermined substances by comparing the magnetic resonance data with a magnetic resonance fingerprinting dictionary (144).

公开(公告)号：US10175330B2

公开(公告)日：2019-01-08

申请号：US15513168

申请日：2015-09-17

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Holger Eggers ,  Peter Bornert

IPC: G01V3/00 ,  G01R33/565 ,  G01R33/48 ,  G01R33/563 ,  G01R33/567

Abstract: The invention relates to a method of MR imaging of a body (10) of a patient. It is an object of the invention to provide a method that enables efficient compensation of flow artifacts, especially for MR angiography in combination with Dixon water/fat separation. The method of the invention comprises the steps of: a) generating MR echo signals at two or more echo times by subjecting the portion of the body (10) to a MR imaging sequence of RF pulses and switched magnetic field gradients, wherein the MR imaging sequence is a Dixon sequence; b) acquiring the MR echo signals; c) reconstructing one or more single-echo MR images from the MR echo signals; d) segmenting the blood vessels from the MR images; e) detecting and compensating for blood flow-induced variations of the amplitude or phase in the single-echo MR images within the blood vessel lumen, and f) separating signal contributions from water and fat spins to the compensated single-echo MR images. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

公开(公告)号：US10088543B2

公开(公告)日：2018-10-02

申请号：US14774314

申请日：2014-03-11

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Peter Bornert ,  Mariya Ivanova Doneva ,  Kay Nehrke

IPC: G01V3/00 ,  G01R33/561 ,  G01R33/36 ,  G01R33/385 ,  G01R33/483

Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). The method comprises the steps of: —subjecting the object (10) to an imaging sequence comprising phase-modulated multi-slice RF pulses for simultaneously exciting two or more spatially separate image slices, —acquiring MR signals, wherein the MR signals are received in parallel via a set of at least two RF coils (11, 12, 13) having different spatial sensitivity profiles within the examination volume, and —reconstructing a MR image for each image slice from the acquired MR signals, wherein MR signal contributions from the different image slices are separated on the basis of the spatial sensitivity profiles of the at least two RF coils (11, 12, 13) and on the basis of the phase modulation scheme of the RF pulses. In order to optimize the conditioning of the inverse problem of the MR image reconstruction, the phase-modulation scheme of the RF pulses is derived from the spatial sensitivity profiles of the at least two RF coils (11, 12, 13). Moreover, the invention relates to a MR device for carrying out this method as well as to a computer program to be run on a MR device.

公开(公告)号：US10274562B2

公开(公告)日：2019-04-30

申请号：US14916297

申请日：2014-09-18

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Christian Stehning ,  Holger Eggers ,  Peter Bornert ,  Lingzhi Hu ,  Zhiqiang Hu

IPC: G01R33/48 ,  G01R33/561 ,  G01R33/56

Abstract: A medical imaging system (10) includes a nuclear imaging system (62), a timing optimization unit (40), a magnetic resonance (MR) scanner (12), an MR reconstruction unit (38), and an attenuation map unit (50). The nuclear imaging system (62) receives nuclear decay data and generates at least one nuclear image (64) of a first resolution based on the received nuclear decay data of an imaged subject (16) and an attenuation map (52). The timing optimization unit (40) which selects a first and a second echo time for a modified Dixon (mDixon) pulse sequence and a sufficient number of repetition times (TRs) to generate an image of the subject (16) of at least a first resolution, with the phase angle difference between water and fat at the first and the second echo time being unequal to 0° and 180°. The MR scanner (12) applies the sequence to the subject (16) and receives MR data (32) from the subject. The MR reconstruction unit (38) reconstructs at least one MR image (44) based on the MR data (32). The attenuation map unit (50) constructs the attenuation map (52) based on the reconstructed MR image (44).

公开(公告)号：US11815577B2

公开(公告)日：2023-11-14

申请号：US17432921

申请日：2020-02-18

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Zechen Zhou ,  Peter Bornert

IPC: G01V3/00 ,  G01R33/483 ,  G01R33/561 ,  G01R33/565

CPC classification number: G01R33/4835 ,  G01R33/5611 ,  G01R33/56563

Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). The method comprises the steps of: —generating MR signals by subjecting the object to an imaging sequence, —acquiring MR signal profiles in a Cartesian k-space sampling scheme, wherein each MR signal profile is acquired in the presence of a temporally constant magnetic field gradient along a readout direction and a sinusoidally modulated magnetic field gradient along a phase encoding direction, and—reconstructing an MR image from the acquired MR signal profiles taking the modulation scheme of the magnetic field gradients into account. The invention proposes that the frequency of the sinusoidal modulation of the magnetic field gradient is varied during acquisition of each MR signal profile. Moreover, the invention relates to a MR device for carrying out this method as well as to a computer program to be run on a MR device.

公开(公告)号：US11432736B2

公开(公告)日：2022-09-06

申请号：US16465629

申请日：2017-12-05

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Cristian Lorenz ,  Peter Bornert ,  Tobias Klinder

IPC: A61B5/055 ,  A61B5/00 ,  A61B6/03 ,  A61B6/00 ,  G06T19/00 ,  G01R33/50 ,  G01R33/56

Abstract: The invention provides for a medical imaging system (700) comprising: a memory (734) for storing machine executable instructions (740), a display (732) for rendering a user interface (800), and a processor (730). Execution of the machine executable instructions causes the processor to receive (1000) three dimensional medical image data (746) descriptive of a region of interest (709) of a subject (718). The region of interest comprises a spine (200). Execution of the machine executable instructions further causes the processor to receive (1002) a set of spinal coordinate systems (748) each descriptive of a location and an orientation of spinal vertebrae in the three dimensional medical image data. The set of spinal coordinate systems further comprises a set of spine centerline positions (102) each positioned on a spine centerline (108). Execution of the machine executable instructions further causes the processor to receive (1004) a mapping (750) between the set of spinal coordinate systems and a simplified coordinate system. The simplified coordinate system comprises a spinal height (300) descriptive of a position along the spine centerline. The simplified coordinate system further comprises a rotational orientation relative to a local vertebrae orientation. The simplified coordinate system further comprises an offset from the spine centerline. Execution of the machine executable instructions further cause the processor to repeatedly receive (1006) a simplified coordinate (752) of the simplified coordinate system from the user interface. Execution of the machine executable instructions further cause the processor to repeatedly calculate (1008) a spinal image rendering (754). Calculating the spinal image rendering comprises using the mapping to transform the simplified coordinate into the set of spinal coordinate systems to determine an image location in the three dimensional medical image data. Execution of the machine executable instructions further cause the processor to repeatedly render (1010) the spinal image rendering on the display.

公开(公告)号：US10222437B2

公开(公告)日：2019-03-05

申请号：US15030430

申请日：2014-10-14

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Kay Nehrke ,  Peter Bornert

IPC: G01R33/48 ,  A61B5/055 ,  G01R33/561

Abstract: The invention relates to a method of MR imaging of an object (10) placed in the examination volume of a MR device (1). It is the object of the invention to provide an improved MR-based temperature mapping method. The method of the invention comprises the steps of: subjecting the object (10) to an imaging sequence of RF pulses and switched magnetic field gradients, which imaging sequence is a stimulated echo sequence including: a) at least two preparation RF pulses (a) radiated toward the object (10) during a preparation period (21), and b) one or more reading RF pulses (β) radiated toward the object (10) during an acquisition period (22) temporally subsequent to the preparation period (21); acquiring at least two MR signals during the acquisition period (22), wherein the two MR signals are either (i) a FID signal (I1, FID) and a stimulated echo signal (I2) or (ii) two stimulated echo signals (STE, STE*); and deriving a temperature map indicating the spatial distribution of the temperature within the object (10) from the at least two acquired MR signals. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).