Time-of-flight resolution-adaptive image regularization and filtering in positron emission tomography

    公开(公告)号:US11009615B2

    公开(公告)日:2021-05-18

    申请号:US16470730

    申请日:2017-12-18

    Abstract: A time of flight (TOF) positron emission tomography (PET) image (38) is generated from TOF PET imaging data (10) acquired of a subject using a TOF PET imaging data acquisition device (6). Iterative image reconstruction (30) of the TOF PET imaging data is performed with TOF localization of counts along respective lines of response (LORs) to iteratively update a reconstructed image (32). Values for at least one regularization or filtering parameter are assigned to the TOF PET imaging data or to voxels of the reconstructed image based on an estimated TOF localization resolution for the TOF PET imaging data or voxels. Regularization (34) or filtering (36) of the reconstructed image is performed using the assigned values for the at least one regularization or filtering parameter. In some embodiments, the varying TOF localization resolution for the TOF PET imaging data or voxels is estimated based on related acquisition characteristics such as count rates or operating temperature of the detectors.

    Medical image processing
    4.
    发明授权

    公开(公告)号:US10740877B2

    公开(公告)日:2020-08-11

    申请号:US16082663

    申请日:2017-04-05

    Abstract: Patient imaging systems, such as PET imaging systems, for example, may suffer from the introduction of artificially introduced noise. This noise is, typically, introduced during iterations of reconstruction algorithms, such as the least-squares algorithms, which attempts to recreate a 2D or a 3D image from raw acquisition information. The noise appears as “hot-spots” in the reconstructed image. Approaches to address these artefacts use filtering approaches. Typically, a least-squares reconstruction is supplemented with a penalty term, an approach known as “Relative Difference Penalty”. The penalty parameter causes the reconstruction algorithm to filter more or less strongly at certain regions of the reconstruction. The present application proposes an approach which supplements the penalty term with continuous probability information about the likelihood of an edge being present in a portion of an image.

    Noise-robust real-time extraction of the respiratory motion signal from PET list-data

    公开(公告)号:US11064965B2

    公开(公告)日:2021-07-20

    申请号:US16493060

    申请日:2018-03-26

    Abstract: A respiratory motion signal generation method operates on emission data (22) of an imaging subject in an imaging field of view (FOV) acquired by a positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging device (10). An array of regions (32) is defined in the imaging FOV without reference to anatomy of the imaging subject. For each region of the array of regions defined in the imaging FOV, an activity position versus time curve (54) is computed from the emission data acquired by the PET or SPECT imaging device. Frequency-selective filtering of the activity position versus time curves is performed to generate filtered activity position versus time curves. At least one motion signal (66) is generated by combining the filtered activity position versus time curves of at least a selected sub-set of the regions.

    Combined X-ray and nuclear imaging

    公开(公告)号:US10448909B2

    公开(公告)日:2019-10-22

    申请号:US16082986

    申请日:2017-02-28

    Abstract: The invention relates to a combined imaging detector (110) for the detection of x-ray and gamma quanta. The combined imaging detector (110) is adapted for simultaneous detection of gamma and x-ray quanta. The combined imaging detector (110) includes an x-ray anti-scatter grid (111), a layer of x-ray scintillator elements (112), a first photodetector array (113), a layer of gamma scintillator elements (114), and a second photodetector array (115) that are arranged in a stacked configuration along a radiation-receiving direction (116). The x-ray anti-scatter grid (111) comprises a plurality of septa (117A, B, C) that define a plurality of apertures (118) which are configured to collimate both x-ray quanta and gamma quanta received from the radiation receiving direction (116) such that received gamma quanta are collimated only by the x-ray anti-scatter grid (111). The use of the x-ray anti-scatter grid as a collimator for received gamma quanta results in a significantly lighter combined imaging detector.

    NUCLEAR IMAGING SYSTEM
    8.
    发明申请
    NUCLEAR IMAGING SYSTEM 审中-公开
    核成像系统

    公开(公告)号:US20150003591A1

    公开(公告)日:2015-01-01

    申请号:US14371286

    申请日:2013-01-18

    Abstract: Nuclear Imaging System The invention relates to a nuclear imaging system (1) for imaging an object (3) in an examination region. Multiple x-rays sources (2) generate first radiation being x-ray radiation (5), wherein the x-ray sources are arranged such that the x-ray radiation is indicative of a property of the object. A detection unit (6) detects second radiation (7) from a nuclear element (8), after the second radiation has the traversed the object, and the first radiation generated by the multiple x-ray sources, thereby inherently registering the detection of the first radiation and the second radiation. A reconstruction unit (9) reconstructs a corrected nuclear image of the object based on the detected first radiation and the detected second radiation, wherein the nuclear image is corrected with respect to the property of the object and, because of the inherent registration, does not comprise image artifacts caused by registration errors.

    Abstract translation: 核成像系统本发明涉及一种用于对检查区域中的物体(3)进行成像的核成像系统(1)。 多个x射线源(2)产生作为X射线辐射(5)的第一辐射,其中x射线源被布置成使得x射线辐射指示物体的特性。 检测单元(6)在第二辐射已经穿过物体之后从核元件(8)检测第二辐射(7),并且由多个X射线源产生的第一辐射检测到, 第一次辐射和第二次辐射。 重建单元(9)基于检测到的第一辐射和检测到的第二辐射来重构物体的校正核图像,其中核图像相对于物体的属性被校正,并且由于固有的注册,不 包括由注册错误引起的图像伪影。

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