公开(公告)号：US20150080720A1

公开(公告)日：2015-03-19

申请号：US14396066

申请日：2013-04-22

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Ming De Lin ,  Ewald Roessl ,  Carsten Oliver Schirra

IPC: A61B6/00 ,  G06T11/00 ,  A61B5/00 ,  G06T7/00

CPC classification number: A61B6/481 ,  A61B5/4839 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/463 ,  A61B6/482 ,  A61B6/487 ,  A61B6/5205 ,  A61B6/5217 ,  G06T7/0012 ,  G06T11/005 ,  G06T2207/10081

Abstract: An imaging system (100) includes a radiation source (108) that emits radiation that traverses an examination region and imageable drug eluting beads in tissue of interest located therein, a spectral detector array (110) detects radiation traversing the examination region and generates a signal indicative thereof, spectral processing circuitry (117) that spectrally resolves the signal based on a plurality of thresholds (122), and a reconstructor (128) that generates spectral volumetric image data corresponding the imageable drug eluting beads based on the spectrally resolved signal.

Abstract translation: 成像系统（100）包括辐射源（108），辐射源（108）发射穿过检查区域的辐射并且位于其中的感兴趣组织中的可成像药物洗脱珠，光谱检测器阵列（110）检测穿过检查区域的辐射，并产生信号 基于多个阈值（122）光谱解析信号的光谱处理电路（117），以及基于光谱解析信号产生对应于可成像药物洗脱珠的光谱体积图像数据的重建器（128）。

公开(公告)号：US20190251711A1

公开(公告)日：2019-08-15

申请号：US16333612

申请日：2017-09-28

Applicant: KONINKLIJKE PHILIPS N.V. ,  Yale University

Inventor： John Treilhard ,  Ming De Lin ,  Jean-François Geschwind ,  James Duncan ,  Susanne Smolka

IPC: G06T11/00 ,  G06T7/00 ,  G06T7/12 ,  G06T7/143

CPC classification number: G06T11/003 ,  G06T7/0014 ,  G06T7/0016 ,  G06T7/12 ,  G06T7/143 ,  G06T7/344 ,  G06T2200/24 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10121 ,  G06T2207/20076 ,  G06T2207/20221 ,  G06T2207/30056 ,  G06T2207/30096

Abstract: In an image guidance method, a stream of cone-beam computed tomography (CBCT) images of an anatomical organ is acquire using a CBCT imaging device (34). For each CBCT image (44), the surface of the organ in the CBCT image is segmented to generate a segmented surface (70) of the anatomical organ in the CBCT image. Occluded shape reconstruction (66) using a statistical shape prior (68) may be used to reconstruct a missing or occluded surface portion. A pre-operative medical image (12) of the anatomical organ and the CBCT image are spatially registered by warping one of the images to the other of the images using point set registration of a segmented surface (30) of the organ in the preoperative medical image and the segmented surface of the organ in the CBCT image. A fused image (82) is displayed that combines the warped image and the other image.

公开(公告)号：US11288846B2

公开(公告)日：2022-03-29

申请号：US16333612

申请日：2017-09-28

Applicant: KONINKLIJKE PHILIPS N.V. ,  Yale University

Inventor： John Treilhard ,  Ming De Lin ,  Jean-François Geschwind ,  James Duncan ,  Susanne Smolka

IPC: G06T11/00 ,  G06T7/00 ,  G06T7/12 ,  G06T7/143 ,  G06T7/33

Abstract: In an image guidance method, a stream of cone-beam computed tomography (CBCT) images of an anatomical organ is acquired using a CBCT imaging device (34). For each CBCT image (44), the surface of the organ in the CBCT image is segmented to generate a segmented surface (70) of the anatomical organ in the CBCT image. Occluded shape reconstruction (66) using a statistical shape prior (68) may be used to reconstruct a missing or occluded surface portion. A pre-operative medical image (12) of the anatomical organ and the CBCT image are spatially registered by warping one of the images to the other of the images using point set registration of a segmented surface (30) of the organ in the preoperative medical image and the segmented surface of the organ in the CBCT image. A fused image (82) is displayed that combines the warped image and the other image.

公开(公告)号：US10231684B2

公开(公告)日：2019-03-19

申请号：US14396066

申请日：2013-04-22

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Ming De Lin ,  Ewald Roessl ,  Carsten Oliver Schirra

IPC: A61B6/00 ,  A61B5/00 ,  G06T7/00 ,  G06T11/00 ,  A61B6/03

Abstract: An imaging system (100) includes a radiation source (108) that emits radiation that traverses an examination region and imageable drug eluting beads in tissue of interest located therein, a spectral detector array (110) detects radiation traversing the examination region and generates a signal indicative thereof, spectral processing circuitry (117) that spectrally resolves the signal based on a plurality of thresholds (122), and a reconstructor (128) that generates spectral volumetric image data corresponding the imageable drug eluting beads based on the spectrally resolved signal.

公开(公告)号：US11172896B2

公开(公告)日：2021-11-16

申请号：US15551925

申请日：2015-12-04

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Christian Haase ,  Dirk Schaefer ,  Eberhard Sebastian Hansis ,  Tobias Klinder ,  Michael Grass ,  Ming De Lin

IPC: A61B6/00 ,  A61B6/03 ,  A61K49/04 ,  A61M5/00 ,  G16H20/17 ,  G16H30/20

Abstract: The present invention is directed towards a system and method for transarterial chemoembolization using differently sized drug-eluting microsphere beads filled with drugs and determining a delivered drug concentration using an imaging system.