公开(公告)号：US11883231B2

公开(公告)日：2024-01-30

申请号：US17045215

申请日：2019-03-28

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Nicole Schadewaldt ,  Cristian Lorenz ,  Alexander Schmidt-Richberg ,  Tobias Klinder

IPC: A61B8/08 ,  A61B8/06 ,  A61B8/00

CPC classification number: A61B8/0866 ,  A61B8/06 ,  A61B8/0883 ,  A61B8/483 ,  A61B8/488 ,  A61B8/5215 ,  A61B8/565

Abstract: A system for generating ultrasound data in respect of an anatomical body being scanned makes use of a predetermined scan protocol, which specifies a sequence of types of ultrasound scan of structures of interest. These types may for example be different imaging modalities (static, dynamic, 2D, 3D etc.) which are most appropriate for viewing different structures within the anatomical body. From received ultrasound images, a model is used to identify the structures of interest within the ultrasound images. The best images for creating the types of scan of the protocol are then identified and a sequence is compiled of those best images. In this way, a sequence is created which combines different types of scan, in a structured way according to a predetermined protocol. This makes the analysis of the sequence most intuitive for a user, and simplifies comparison between different sequences.

公开(公告)号：US11880432B2

公开(公告)日：2024-01-23

申请号：US17426759

申请日：2020-01-21

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Matthias Lenga ,  Rafael Wiemker ,  Tobias Klinder ,  Marten Bergtholdt ,  Heike Carolus

IPC: G06V10/776 ,  G06F18/2413 ,  G06N20/00 ,  G06V10/82 ,  G06T3/00

CPC classification number: G06F18/2413 ,  G06N20/00 ,  G06T3/0093 ,  G06V10/776 ,  G06V10/82

Abstract: Presented are concepts for obtaining a confidence measure for a machine learning model. One such concept process input data with the machine learning model to generate a primary result. It also generate a plurality of modified instances of the input data and processes the plurality of modified instances of the input data with the machine learning model to generate a respective plurality of secondary results. A confidence measure relating to the primary result is determined based on the secondary results.

公开(公告)号：US10729340B2

公开(公告)日：2020-08-04

申请号：US14782605

申请日：2014-04-09

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Tobias Klinder ,  Holger Schmitt ,  Michael Grass

IPC: A61B5/026 ,  G16H40/63 ,  A61B5/02 ,  G16H50/50 ,  G16H30/40 ,  A61B5/06 ,  A61B17/00 ,  A61B90/00 ,  A61B8/12 ,  A61B5/107 ,  A61B5/00 ,  A61B8/08 ,  A61B34/20 ,  A61B34/10 ,  A61B8/00

Abstract: A medical system includes a medical instrument (102) configured for interventional deployment and a shape sensing system (104) mounted on or in the medical instrument and configured to measure a shape of the medical instrument during the interventional deployment. An imaging device (106) is mounted on or in the medical instrument and configured to image a lumen in which the imaging device is deployed. A registration module (140) is configured to register the shape of the medical instrument to an image of the lumen at a particular time to reconstruct a three-dimensional geometry of the lumen, accounting for motion.

公开(公告)号：US10552958B2

公开(公告)日：2020-02-04

申请号：US15570620

申请日：2016-04-26

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Eberhard Sebastian Hansis ,  Holger Schmitt ,  Michael Grass ,  Dirk Schaefer ,  Hanno Heyke Homann ,  Tobias Klinder ,  Christian Haase

IPC: G06K9/00 ,  G06T7/00 ,  G06T17/20 ,  A61B5/0215 ,  A61B5/026 ,  A61B5/00 ,  A61B6/03 ,  A61B6/00 ,  G06T7/60

Abstract: The present invention relates to a device (1) for fractional flow reserve determination, the device (1) comprising: a model source (10) configured to provide a first three-dimensional model (3DM1) of a portion of an imaged vascular vessel tree (VVT) surrounding a stenosed vessel segment (SVS) and configured to provide a second three-dimensional model (3DM2) of a pressure wire insertable into the vascular vessel tree (VVT); and a processor (20) configured to calculate a first blood flow (Q1) through the stenosed vessel segment (SVS) with the pressure wire (PW) inserted into the vascular vessel tree (VVT) based on the first and the second three-dimensional model and to calculate a second blood flow (Q2) through the stenosed vessel segment (SVS) without the pressure wire (PW) inserted into the vascular vessel tree (VVT) based on the first three-dimensional model (3DM1) and to determine a first fractional flow reserve value (FFR1) to be measured with the pressure wire (PW) inserted into the vascular vessel tree (VVT) based on the first blood flow (Q1) and to determine a second fractional flow reserve value (FFR2) to be measured without the pressure wire (PW) inserted into the vascular vessel tree (VVT) based on the second blood flow (Q1).

公开(公告)号：US10290102B2

公开(公告)日：2019-05-14

申请号：US14405007

申请日：2013-06-18

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Cristian Lorenz ,  Sven Kabus ,  Tobias Klinder ,  Jens Von Berg

IPC: G06T7/33 ,  G06T7/00 ,  G06T3/00 ,  G06K9/46 ,  G06T7/20 ,  G06T17/10

Abstract: An image registration apparatus (118) includes an image quality driven image registration determiner (202) that determines an image quality driven image registration for a set of images to register based on a non-rigid registration (204), which includes an optimization of an image similarity term and a regularization term, and a registration steering factor, and a registration component (206) that registers the set of images using the image quality driven image registration. A method determining an image quality driven image registration for a set of images to register based on a non-rigid registration, which includes an optimization of an image similarity term and a regularization term, and a registration steering factor, and registering the set of images using the fidelity driven image registration, generating a set of registered images.

公开(公告)号：US10074207B2

公开(公告)日：2018-09-11

申请号：US15304932

申请日：2015-05-19

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Rafael Wiemker ,  Tobias Klinder ,  Thomas Buelow

IPC: G06T15/08 ,  G06T15/06 ,  G06T7/00 ,  G06T7/187 ,  G06T19/20

CPC classification number: G06T15/06 ,  G06T7/0012 ,  G06T7/187 ,  G06T15/08 ,  G06T19/20 ,  G06T2207/10072 ,  G06T2207/10081 ,  G06T2207/30101 ,  G06T2210/41 ,  G06T2219/2008

Abstract: A method includes obtaining contrast-enhanced image data having a plurality of voxels, each voxel having an intensity value. The method further includes determining a vesselness value for each voxel. The method further includes determining a hypo-density value for each voxel. The method further includes weighting each of the intensity values by a corresponding vesselness value. The method further includes weighting each of the hypo-density values by the corresponding vesselness value. The method further includes combining the weighted intensity values and the weighted hypo-density values, thereby generating composite image data. The method further includes visually displaying the composite image data.

公开(公告)号：US11410305B2

公开(公告)日：2022-08-09

申请号：US16967446

申请日：2019-02-01

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Rafael Wiemker ,  Jörg Sabczynski ,  Tobias Klinder

IPC: G06T7/00 ,  G16H30/40 ,  G06T5/00

Abstract: Iterative material decomposition of multispectral image data includes providing a plurality of spectral images of a region of interest comprising a body part and a plurality of sets of material coefficients for a plurality of materials. Each spectral image is decomposed into a plurality of material images and an offset image. At least one of the material images for each spectral image is manipulated on the basis of at least one topological constraint relating to the body part to determine for each spectral image an updated plurality of material images and an updated offset image. A plurality of spectral images is then recomposed from the corresponding updated plurality of material images and the updated offset. Intensities at image locations are compared, and the updated plurality of material images is modified. The steps are repeated until convergence, and at least one of the recomposed spectral images at convergence is output.

公开(公告)号：US11042987B2

公开(公告)日：2021-06-22

申请号：US16606249

申请日：2018-04-18

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Rafael Wiemker ,  Tobias Klinder ,  Heike Ruppertshofen ,  Nicole Schadewaldt

IPC: G06K9/00 ,  G06T7/12 ,  A61B6/03 ,  G06K9/62

Abstract: A method for modelling a composition of an object of interest comprises segmenting object of interest image data provided by computer tomography image data resulting in a plurality of image segments. A determined Hounsfield density value is then extracted from the object of interest image data for each image segment. A component ratio of at least two component classes is defined for the object of interest, the at least two component classes having different component Hounsfield density values. At least one component class is assigned to each image segment based on the corresponding determined Hounsfield density value resulting in simulated image segments comprising the component Hounsfield density values. The simulated image segments define simulated image data of the object of interest, where a ratio of the assigned component classes corresponds to the component ratio. A deviation between the simulated image data and the object of interest image data is then determined.

公开(公告)号：US10902606B2

公开(公告)日：2021-01-26

申请号：US16060453

申请日：2016-12-19

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Cristian Lorenz ,  Tobias Klinder ,  Holger Schmitt ,  Hannes Nickisch

IPC: G06T7/149 ,  G06T7/11 ,  G06T7/12 ,  G16H50/50 ,  A61B5/026

Abstract: A system (100) for segmenting a coronary artery vessel tree (182) of a patient heart in a three dimensional (3D) cardiac image (120) includes a coronary volume definition unit (150) and a coronary artery segmentation unit (180). The coronary volume definition unit (150) sets a spatial boundary (210, 220) from internal and external surfaces of heart tissues in the 3D cardiac image based on a fitted heart model (200). The coronary artery segmentation unit (180) segments the coronary artery vessel tree (182) in the 3D cardiac image using a segmentation algorithm with a search space limited by the spatial boundary set from the internal and external surfaces of the heart tissues.

公开(公告)号：US10758212B2

公开(公告)日：2020-09-01

申请号：US14361884

申请日：2012-11-28

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Rafael Wiemker ,  Kongkuo Lu ,  Sheng Xu ,  Tobias Klinder ,  Martin Bergtholdt

IPC: A61B10/02 ,  G06F3/0481 ,  G06F3/0484 ,  G06T19/00 ,  A61B34/10 ,  A61B34/00 ,  G16H40/40 ,  A61B90/00

Abstract: A planning tool, system and method include a processor (114) and memory (116) coupled to the processor which stores a planning module (144). A user interface (120) is coupled to the processor and configured to permit a user to select a path through a pathway system (148). The planning module is configured to upload one or more slices of an image volume (111) corresponding to a user-controlled cursor point (108) guided using the user interface such that as the path is navigated the one or more slices are updated in accordance with a depth of the cursor point in the path.