公开(公告)号：US20160128641A1

公开(公告)日：2016-05-12

申请号：US14934255

申请日：2015-11-06

申请人： KONINKLIJKE PHILIPS N.V.

发明人： Pedro Miguel FONSECA ,  Reinder HAAKMA ,  Ronaldus Maria AARTS ,  Xi LONG

IPC分类号： A61B5/00 ,  A61B5/113 ,  A61B5/08 ,  A61B5/0245 ,  A61B5/0402

CPC分类号： A61B5/7278 ,  A61B5/0245 ,  A61B5/0402 ,  A61B5/0809 ,  A61B5/0816 ,  A61B5/1118 ,  A61B5/1135 ,  A61B5/4806 ,  A61B5/4812 ,  A61B5/7203 ,  A61B5/7242 ,  A61B5/725 ,  A61B5/7257 ,  A61B5/726

摘要： An actigraphy method includes receiving a physiological parameter signal as a function of time for a physiological parameter other than body motion (such as electrocardiography or a respiration monitor), computing a body motion artifact (BMA) signal as a function of time from the physiological parameter signal (for example, using a local signal power signal, a local variance signal, a short-time Fourier transform, or a wavelet transform over epochs of duration on order a few minutes or less), and computing an actigraphy signal as a function of time from the BMA signal, for example by applying a linear transform to the BMA signal and optionally applying filtering such as median removal and/or high-pass filtering.

摘要翻译： 一种动作方法包括接收生理参数信号作为身体运动以外的生理参数（如心电图或呼吸监测器）作为时间的函数，根据生理参数计算身体运动假象（BMA）信号作为时间的函数 信号（例如，使用本地信号功率信号，局部方差信号，短时傅立叶变换或在几分钟或更短的时间段上的时间周期上的小波变换），以及计算作为 例如通过对BMA信号应用线性变换并且可选地应用诸如中值去除和/或高通滤波的滤波来从BMA信号获得时间。

公开(公告)号：US20170360308A1

公开(公告)日：2017-12-21

申请号：US15536680

申请日：2015-12-10

申请人： KONINKLIJKE PHILIPS N.V.

发明人： Pedro Miguel FONSECA ,  Xi LONG ,  Nicolaas Gregorius Petrus DEN TEULING ,  Reinder HAAKMA ,  Ronaldus Maria AARTS

IPC分类号： A61B5/024 ,  A61B5/08 ,  A61B5/00

摘要： The present disclosure pertains to a system configured to determine one or more parameters based on cardiorespiratory information from a subject and determine sleep stage classifications based on a discriminative undirected probabilistic graphical model such as Conditional Random Fields using the determined parameters. The system is advantageous because sleep is a structured process in which parameters determined for individual epochs are not independent over time and the system determines the sleep stage classifications based on parameters determined for a current epoch, determined relationships between parameters, sleep stage classifications determined for previous epochs, and/or other information. The system does not assume that determined parameters are discriminative during an entire sleep stage, but maybe indicative of a sleep stage transition alone. In some embodiments, the system comprises one or more sensors, one or more physical computer processors, electronic storage, and a user interface.

公开(公告)号：US20170360363A1

公开(公告)日：2017-12-21

申请号：US15536158

申请日：2015-12-10

申请人： KONINKLIJKE PHILIPS N.V.

发明人： Pedro Miguel FONSECA ,  Xi LONG ,  Nicolaas Gregorius Petrus DEN TEULING ,  Reinder HAAKMA ,  Ronaldus Maria AARTS

IPC分类号： A61B5/00 ,  A61B5/024 ,  A61B5/08 ,  A61B5/0476

CPC分类号： A61B5/4812 ,  A61B5/024 ,  A61B5/0476 ,  A61B5/08 ,  A61B5/4806 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/7282 ,  G16H40/63 ,  G16H50/20

摘要： The present disclosure pertains to a system configured to detect slow wave sleep and/or non-slow wave sleep in a subject during a sleep session based on a predicted onset time of slow wave sleep and/or a predicted end time of slow wave sleep that is determined based on changes in cardiorespiratory parameters of the subject. Cardiorespiratory parameters in a subject typically begin to change before transitions between non-slow wave sleep and slow wave sleep. Predicting this time delay between the changes in the cardiorespiratory parameters and the onset and/or end of slow wave sleep facilitates better (e.g., more sensitive and/or more accurate) determination of slow wave sleep and/or non-slow wave sleep.

公开(公告)号：US20160310696A1

公开(公告)日：2016-10-27

申请号：US15105635

申请日：2014-12-08

申请人： KONINKLIJKE PHILIPS N.V.

发明人： Pedro Miguel FONSECA ,  Gary Nelson GARCIA MOLINA ,  Reinder HAAKMA

IPC分类号： A61M21/02 ,  A61B5/0205 ,  A61B5/0295 ,  A61B5/11 ,  A61B5/04 ,  A61B5/00 ,  A61B5/08

CPC分类号： A61M21/02 ,  A61B5/0077 ,  A61B5/0205 ,  A61B5/0261 ,  A61B5/0295 ,  A61B5/04001 ,  A61B5/08 ,  A61B5/1102 ,  A61B5/4812 ,  A61B5/681 ,  A61M2021/0016 ,  A61M2021/0022 ,  A61M2021/0027 ,  A61M2021/0044 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/005 ,  A61M2230/04 ,  A61M2230/40 ,  A61N2/006

摘要： Systems and methods for providing sensory stimuli induce and/or enhance sleep and/or slow wave neural activity of a subject during sleep. Operation of the systems and methods is based on measured information related to cardiac attributes and/or respiratory attributes of the subject, and corresponding cardiac parameters and/or respiratory parameters based thereon. Attributes may be measured and/or monitored via one or more sensors, e.g. worn on an extremity of the subject and/or placed at a distance from the subject. Sensory stimulation delivered to the subject during specific targeted periods of sleep may enhance slow wave neural activity.

摘要翻译： 用于提供感觉刺激的系统和方法在睡眠期间诱导和/或增强受试者的睡眠和/或慢波神经活动。 系统和方法的操作基于与受试者的心脏属性和/或呼吸属性相关的测量信息，以及相应的心脏参数和/或呼吸参数。 属性可以通过一个或多个传感器来测量和/或监测，例如， 佩戴在受试者的肢体和/或放置在远离受试者的位置。 在特定目标睡眠期间传递给受试者的感觉刺激可以增强慢波神经活动。