公开(公告)号：US20180264064A1

公开(公告)日：2018-09-20

申请号：US15742391

申请日：2016-07-08

Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINE

Inventor： Jin Yeul MA ,  Jung Hyun KIM ,  Jong Wook JEON ,  You Chang OH ,  Won Kyung CHO ,  Youn Hwan HWANG ,  Nam Hui YIM ,  Jae Myung YOO

IPC: A61K36/77 ,  A61K9/00 ,  A61P27/02

CPC classification number: A61K36/77 ,  A61K8/9789 ,  A61K9/0048 ,  A61K9/08 ,  A61K36/20 ,  A61K47/02 ,  A61K2800/84 ,  A61P27/02 ,  A61Q1/10 ,  A61Q19/005

Abstract: The present invention relates to a pharmaceutical composition for preventing and treating corneal diseases or conjunctival diseases, containing a maple leaf extract as an active ingredient. The maple leaf extract exhibits an effect of inhibiting hyperemia in the eyeball in which hyperemia has been induced and an effect of inhibiting angiogenesis in the eyeball in which corneal damage has been induced, thus being effectively used in a pharmaceutical composition for preventing and treating corneal diseases or conjunctival diseases.

公开(公告)号：US20210315957A1

公开(公告)日：2021-10-14

申请号：US17266610

申请日：2020-06-17

Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY ,  KOREA INSTITUTE OF ORIENTAL MEDICINE ,  DAEGU CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

Inventor： Inho CHOI ,  Eun Ju LEE ,  So-young PARK ,  Yong-Ho LEE ,  Jin Yeul MA ,  Won-Kyung CHO ,  Hye Jin YANG

IPC: A61K36/484 ,  A61K9/00 ,  A61K31/353 ,  A61K31/12 ,  A61P21/00 ,  A23L33/00 ,  A23L33/105

Abstract: A pharmaceutical composition and a health functional food composition for preventing, treating, or improving muscular diseases have licorice extract or a fraction thereof, or a compound isolated therefrom or a pharmaceutically acceptable salt thereof, as an active ingredient. The licorice extract or a fraction thereof, the compound or salt thereof induce the myoblasts proliferation and promote the differentiation into myotubes, and since the licorice extract or a fraction thereof, the compound or salt thereof has an excellent effect on regenerating damaged muscles, various muscle diseases are effectively prevented, improved or treated using the composition.

公开(公告)号：US20190328808A1

公开(公告)日：2019-10-31

申请号：US16325958

申请日：2017-08-11

Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINE

Inventor： Jin Yeul MA ,  Kwang Il PARK ,  Yeoun-Hee KIM ,  Tae Woo OH ,  Won Kyung CHO ,  Dong-Gun KIM ,  Eun Hee PARK

IPC: A61K36/20 ,  A23L33/105 ,  A61P27/02

Abstract: The present invention relates to a pharmaceutical composition comprising a maple leaf extract or fraction thereof for preventing or treating a retinal disease, a method for preventing or treating a retinal disease using the pharmaceutical composition, and a food composition comprising a maple leaf extract or fraction thereof for ameliorating the symptoms of a retinal disease.The pharmaceutical composition according to the present invention, which is effective for the treatment of a retinal disease, can be used pharmaceutically as a composition for preventing or treating a retinal disease, and can also be used advantageously as a health functional food.

公开(公告)号：US20160136227A1

公开(公告)日：2016-05-19

申请号：US14547630

申请日：2014-11-19

Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINE

Inventor： Jin Yeul MA ,  Dong Hoon KWAK ,  Ji Hye LEE ,  Dong Gun KIM ,  Tae Soo KIM

IPC: A61K36/9066 ,  A61K36/69 ,  A61K36/888 ,  A61K36/78

CPC classification number: A61K36/9066 ,  A61K36/69 ,  A61K36/78 ,  A61K36/882 ,  A61K2236/00 ,  A61K2300/00

Abstract: Disclosed herein are a pharmaceutical composition for the prevention or treatment of obesity comprising an extract of a mixture comprising Saururi chinensis Baill., Curcumae Longae Rhizoma, and Polygalae Radix, or an extract of a mixture comprising Saururi chinensis Baill., Curcumae Longae Rhizoma, Polygalae Radix, and Acori Gramineri Rhizoma; a food composition comprising the extract of the mixture; and a method of manufacturing the extracts of the mixture. The extracts of the present invention can inhibit fat generation without adverse effects such as cellular toxicity and thus can be widely used for the prevention, improvement, or treatment of obesity or obesity-related diseases.

Abstract translation: 本文公开了一种用于预防或治疗肥胖症的药物组合物，其包含含有中国中华ensis ill，姜黄和多ae ix的混合物的提取物，或包含中华ensis，，，oma，，a a a ;和Ac; 包含所述混合物的提取物的食物组合物; 以及制造混合物提取物的方法。 本发明的提取物可以抑制脂肪生成，而不会产生细胞毒性等不良影响，因此可广泛用于预防，改善或治疗肥胖症或肥胖相关疾病。

公开(公告)号：US20130287761A1

公开(公告)日：2013-10-31

申请号：US13926412

申请日：2013-06-25

Applicant: Korea Institute of Oriental Medicine

Inventor： Jin Yeul MA ,  Jae Hoon LEE ,  Young Ran UM ,  Ji Hye LEE

IPC: A61K36/9068 ,  A61K36/725 ,  A61K36/65 ,  A61K36/54 ,  A61K36/484

CPC classification number: A61K36/9068 ,  A61K35/745 ,  A61K35/747 ,  A61K36/484 ,  A61K36/488 ,  A61K36/54 ,  A61K36/65 ,  A61K36/725 ,  A61K2300/00

Abstract: The present invention relates to lactic acid fermented Galgeuntang, and a composition comprising the said lactic acid bacteria fermented Galgeuntang or Galgeuntang as an active ingredient, more particularly, to lactic acid fermented Galgeuntang prepared by the steps of inoculating lactic acid bacteria to Galgeuntang, culturing thereof, and fermenting thereof, and a composition for preventing or treating liver toxicity comprising the said fermented Galgeuntang or Galgeuntang. The composition of the present invention has treatment effect on liver toxicity, so that it can be effectively used as a liver function recovering agent or health food for liver function recovery.

Abstract translation: 本发明涉及乳酸发酵的Galgeuntang，以及包含所述乳酸菌发酵的Galgeuntang或Galgeuntang作为活性成分的组合物，更具体地，涉及通过将乳酸菌接种到Galgeuntang，培养它们的步骤制备的乳酸发酵Galgeuntang ，及其发酵，以及用于预防或治疗肝毒性的组合物，其包含所述发酵的Galgeuntang或Galgeuntang。 本发明的组合物对肝毒性具有治疗作用，因此可以有效地用作肝功能恢复剂或保健食品用于肝功能恢复。