公开(公告)号：US10357528B2

公开(公告)日：2019-07-23

申请号：US15742391

申请日：2016-07-08

Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINE

Inventor： Jin Yeul Ma ,  Jung Hyun Kim ,  Jong Wook Jeon ,  You Chang Oh ,  Won Kyung Cho ,  Youn Hwan Hwang ,  Nam Hui Yim ,  Jae Myung Yoo

IPC: A61P27/02 ,  A61K36/20 ,  A61K9/08 ,  A61K36/77 ,  A61K9/00 ,  A61K47/02

Abstract: The present invention relates to a pharmaceutical composition for preventing and treating corneal diseases or conjunctival diseases, containing a maple leaf extract as an active ingredient. The maple leaf extract exhibits an effect of inhibiting hyperemia in the eyeball in which hyperemia has been induced and an effect of inhibiting angiogenesis in the eyeball in which corneal damage has been induced, thus being effectively used in a pharmaceutical composition for preventing and treating corneal diseases or conjunctival diseases.

公开(公告)号：US09844575B2

公开(公告)日：2017-12-19

申请号：US14759471

申请日：2014-01-10

Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINE

Inventor： Jin Sook Kim ,  Jung Hyun Kim ,  Chan Sik Kim ,  Young Sook Kim ,  Eun Jin Shon ,  Yun Mi Lee ,  Dong Ho Jung ,  Ik Soo Lee ,  Gyu Hyeong Jo ,  Joo Hwan Kim

IPC: A61K36/00 ,  A61K36/25 ,  A61K31/155 ,  A61K36/708 ,  A61K36/488 ,  A61K36/16 ,  A61K36/482 ,  A61K36/45 ,  A61K36/73 ,  A61K36/87 ,  A61K36/718 ,  A23L33/105

CPC classification number: A61K36/25 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/155 ,  A61K36/16 ,  A61K36/45 ,  A61K36/482 ,  A61K36/488 ,  A61K36/708 ,  A61K36/718 ,  A61K36/73 ,  A61K36/87 ,  A61K2300/00

Abstract: The present invention relates to a pharmaceutical composition and a health functional food composition for prevention, treatment or amelioration of diabetic complications or angioedema containing a mixed extract of Hedera helix leaves and Coptis chinensis as an active ingredient. More specifically, the present invention relates to a pharmaceutical composition and a health functional food composition for prevention, treatment or amelioration of diabetic complications or angioedema further containing an extract of Rheum palmatum, Puerariae radix, Ginkgo leaves, Cassiae semen, blueberry, bilberry, raspberry, or grape seeds as an active ingredient, in addition to the mixed extract of Hedera helix leaves and Coptis chinensis.