公开(公告)号：US20160054335A1

公开(公告)日：2016-02-25

申请号：US14779898

申请日：2014-03-25

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Cheolju LEE ,  Ji Eun LEE ,  Hye Jung KIM ,  Se Joon WOO ,  Jeeyun AHN ,  Kyu Hyung PARK ,  Eui Jin SUH

IPC: G01N33/68 ,  C07K16/18 ,  G01N33/50

CPC classification number: G01N33/6887 ,  C07K16/18 ,  C07K2317/21 ,  G01N33/5023 ,  G01N33/6848 ,  G01N33/6893 ,  G01N2333/4712 ,  G01N2500/00 ,  G01N2800/164 ,  G01N2800/7042

Abstract: A biomarker for diagnosing age-related macular degeneration includes a vinculin protein, and a diagnostic kit, a diagnostic method, and a method of screening a therapeutic material for age-related macular degeneration use the biomarker. The diagnostic kit and the diagnostic method of age-related macular degeneration are novel immunological diagnostic tools using the plasma of a patient, and have remarkable sensitivity that enables simple analysis of plasma without a biopsy, and thus can be useful for diagnosing age-related macular degeneration.

Abstract translation: 用于诊断年龄相关性黄斑变性的生物标志物包括纽蛋白蛋白，诊断试剂盒，诊断方法和筛选年龄相关性黄斑变性治疗材料的方法使用生物标志物。 诊断试剂盒和年龄相关性黄斑变性的诊断方法是使用患者血浆的新型免疫诊断工具，具有显着的灵敏度，能够在没有活检的情况下简单分析血浆，因此可用于诊断年龄相关性黄斑 退化。