公开(公告)号：US20220133835A1

公开(公告)日：2022-05-05

申请号：US17518799

申请日：2021-11-04

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob HAM ,  Taejung KIM ,  Young Tae PARK ,  Pilju CHOI ,  Ji-yool KIM ,  Cheol Hee YOON ,  Haneul JU

IPC: A61K36/906 ,  A61P3/10

Abstract: Provided are a pharmaceutical composition for preventing or treating diabetes and a method of preventing or treating diabetes in a subject by using the pharmaceutical composition, the pharmaceutical composition including a ginger extract, as an active ingredient, obtained by microwave irradiation, under pressure, of ginger, an extract thereof, or a combination thereof.

公开(公告)号：US20210196608A1

公开(公告)日：2021-07-01

申请号：US17138312

申请日：2020-12-30

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob HAM ,  Taejung KIM ,  Bong Chul CHUNG ,  Sungdo HA ,  Seok LEE ,  Jin-Chul KIM ,  Pilju CHOI ,  Bong Geun SONG

IPC: A61K8/49 ,  C07D311/80 ,  A23L33/105 ,  A23L5/30

Abstract: Provided are: a method of preparing a Cannabis processed product having an increased CBN content in an efficient and economic manner, through cyclization of CBD and aromatization of THC by continuous microwave irradiation of a Cannabis extract; and use of a processed product having an increased CBN content prepared by the method, a fraction thereof, and a single ingredient of CBN, in foods, drugs, and cosmetics.

公开(公告)号：US20210308648A1

公开(公告)日：2021-10-07

申请号：US17221591

申请日：2021-04-02

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob HAM ,  Taejung KIM ,  Bong Chul CHUNG ,  Sungdo HA ,  Seok LEE ,  Young Tae PARK ,  Pilju CHOI

IPC: B01J19/12

Abstract: A large capacity natural material composition conversion apparatus using a microwave with a preset pressure function includes a chamber including a sealed reaction space accommodating a material, an radiator configured to heat the material by radiating a microwave into the reaction space, a pressure regulator configured to regulate a pressure of the reaction space by supplying a gas into the reaction space, and a controller configured to control the pressure regulator and the radiator, and preliminarily increase a pressure of the reaction space by controlling the pressure regulator before heating the material.

公开(公告)号：US20190254989A1

公开(公告)日：2019-08-22

申请号：US16282203

申请日：2019-02-21

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob HAM ,  Young Tae PARK ,  Taejung KIM ,  Young seok KIM ,  Pilju CHOI ,  Kyusun KIM ,  SeonJun CHOI ,  BongGeun SONG ,  Kisung KANG ,  Buyng Su HWANG ,  Dahae LEE ,  Jihoon SONG

IPC: A61K31/122 ,  A61K33/243 ,  A61P13/12 ,  A61K31/09 ,  A61K36/062 ,  A61K31/05

Abstract: A composition for preventing or reducing nephrotoxicity, and use thereof are provided, the composition including a Hypoxylon truncatum extract or an active component thereof.

公开(公告)号：US20170007653A1

公开(公告)日：2017-01-12

申请号：US15201819

申请日：2016-07-05

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob HAM ,  Taejung KIM ,  Kwantae KIM ,  Pilju CHOI ,  Buyng Su HWANG ,  Young Seok KIM

IPC: A61K36/258

CPC classification number: A61K36/258 ,  A61K9/00 ,  A61K2236/00

Abstract: Provided are a pharmaceutical composition for preventing or treating skin cancer and a method of preventing or treating skin cancer in a subject by using the pharmaceutical composition, wherein the pharmaceutical composition includes a Panax spp. plant extract as an active ingredient.

Abstract translation: 本发明提供一种用于预防或治疗皮肤癌的药物组合物，以及通过使用药物组合物预防或治疗受试者的皮肤癌的方法，其中所述药物组合物包括Panax spp。 植物提取物作为活性成分。

公开(公告)号：US20220314191A1

公开(公告)日：2022-10-06

申请号：US17590292

申请日：2022-02-01

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Taejung KIM ,  Jungyeob HAM ,  Young Tae PARK ,  Pilju CHOI ,  Joonyeon CHANG

IPC: B01J19/12 ,  B01J19/24

Abstract: According to an aspect of the disclosure, there is provided a microwave reactor including a container for storing a bath fluid, a tube including an inlet at one end through which a target fluid is introduced, an outlet at another end through which the target fluid is discharged, wherein at least a portion of the tube is submerged in the bath fluid, and at least one radiator located outside the container and configured to irradiate microwaves into the container.

公开(公告)号：US20210100864A1

公开(公告)日：2021-04-08

申请号：US17035690

申请日：2020-09-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob HAM ,  Taejung KIM ,  Bong Chul CHUNG ,  Seok LEE ,  Bong Geun SONG ,  Sungdo HA ,  Young Tae PARK ,  Pilju CHOI ,  Hoon RYU

IPC: A61K36/185 ,  A61K31/05 ,  A23L33/105 ,  A61K8/34 ,  A61K8/9789 ,  B01J19/12

Abstract: Provided are: a method of preparing a cannabis processed product having an increased CBD content in an efficient and economic manner, through a decarboxylation reaction by continuous microwave irradiation of a cannabis extract; and use of a processed product having an increased CBD content prepared by the method, a fraction thereof, and a single ingredient of CBD, in foods, drugs, and cosmetics.

公开(公告)号：US20210002247A1

公开(公告)日：2021-01-07

申请号：US16916920

申请日：2020-06-30

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob HAM ,  Taejung KIM ,  Bong Chul CHUNG ,  Sungdo HA ,  Seok LEE ,  Deok Ha WOO ,  Pilju CHOI ,  Bong Geun SONG

IPC: C07D311/80 ,  A61K8/49 ,  A61Q19/00 ,  A23L33/105 ,  B01D11/02

Abstract: Provided are a method of preparing a cannabis processed product having an increased Δ9-THC content in an efficient and economic manner, through a cyclization reaction by microwave irradiation of cannabis using various extraction solvents, and use of the processed product having an increased Δ9-THC content prepared by the method, a fraction thereof, and a single ingredient of THC, in foods, drugs, and cosmetics.

公开(公告)号：US20180280456A1

公开(公告)日：2018-10-04

申请号：US15935634

申请日：2018-03-26

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob HAM ,  Bong Chul CHUNG ,  Taejung KIM ,  Pilju CHOI ,  Ki Sung KANG ,  Buyng Su HWANG ,  Kyu Sun KIM

IPC: A61K36/062 ,  A61P3/10 ,  A61K31/122 ,  A61K31/05

Abstract: Provided are a composition for stimulating insulin secretion from cells, the composition including a Hypoxylon truncatum extract or an active ingredient thereof, and a method of stimulating insulin secretion from cells.