公开(公告)号：US20230278963A1

公开(公告)日：2023-09-07

申请号：US18011460

申请日：2021-06-18

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ae Nim PAE ,  Yun Kyung KIM ,  Sang Min LIM ,  Sungsu LIM ,  Haeun LEE ,  Woo Seung SON ,  Hye Yeon LEE

IPC: C07D237/14

CPC classification number: C07D237/14

Abstract: Provided are novel oxopyridazinyl-phenyl-carbonohydrazonoyl dicyanide compounds and uses thereof.

公开(公告)号：US20230295095A1

公开(公告)日：2023-09-21

申请号：US18011459

申请日：2021-06-18

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ae Nim PAE ,  Yun Kyung KIM ,  Sang Min LIM ,  Sungsu LIM ,  Haeun LEE ,  Woo Seung SON ,  Hye Yeon LEE

IPC: C07D217/24 ,  C07D235/26 ,  C07D263/58 ,  C07D277/68 ,  C07D215/227 ,  C07D471/04

CPC classification number: C07D217/24 ,  C07D235/26 ,  C07D263/58 ,  C07D277/68 ,  C07D215/227 ,  C07D471/04

Abstract: Provided are novel fused-heterocyclyl-carbonohydrazonoyl dicyanide compounds and uses thereof.

公开(公告)号：US20230278965A1

公开(公告)日：2023-09-07

申请号：US18011469

申请日：2021-06-18

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ae Nim PAE ,  Yun Kyung KIM ,  Sang Min LIM ,  Sungsu LIM ,  Haeun LEE ,  Woo Seung SON ,  Hye Yeon LEE

IPC: C07D241/24 ,  C07D213/75 ,  C07D401/14 ,  C07D409/12 ,  C07D417/12 ,  C07D413/12 ,  C07D237/08 ,  C07D333/60 ,  C07D277/56

CPC classification number: C07D241/24 ,  C07D213/75 ,  C07D401/14 ,  C07D409/12 ,  C07D417/12 ,  C07D413/12 ,  C07D237/08 ,  C07D333/60 ,  C07D277/56

Abstract: Provided are novel carbonohydrazonoyl dicyanide compounds including two or more aryl or heteroaryl groups connected via a linker and uses thereof.

公开(公告)号：US20220396553A1

公开(公告)日：2022-12-15

申请号：US17415382

申请日：2018-12-26

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ae Nim PAE ,  Yun Kyung KIM ,  Sang Min LIM ,  Sungsu LIM ,  Jihye SEONG ,  Jae Wook LEE ,  Ji Yeon SONG ,  Seulgi SHIN ,  Hyean Jeong JEONG ,  Woo Seung SON ,  Haeun LEE ,  Da Mi LIM ,  Seok Kyu KIM ,  Jee Yun AHN ,  Chae Won KIM ,  Ashwini Machhindra LONDHE ,  Lizaveta GOTINA ,  Hyojin KIM ,  Hye Yeon LEE ,  Nam Gyung KIM ,  Eunji CHA ,  Kunhee KIM ,  Ji Woong LIM

IPC: C07D241/42 ,  C07D239/34 ,  C07D239/30 ,  C07D239/26 ,  C07D277/28 ,  C07C255/66 ,  C07D487/04 ,  C07D471/04 ,  C07D231/12 ,  C07D209/14 ,  C07D231/56 ,  C07D215/38 ,  C07D417/12 ,  C07D417/04 ,  C07D277/82 ,  C07D237/14

Abstract: The present invention relates to novel hydrazone derivatives in which a terminal amine group is substituted with an aryl group or a heteroaryl group, and uses thereof.

公开(公告)号：US20170354650A1

公开(公告)日：2017-12-14

申请号：US15403404

申请日：2017-01-11

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyunah CHOO ,  Sun-Joon MIN ,  Yun Kyung KIM ,  Hoon RYU ,  Hyemyung SEO ,  Juhyeon KIM ,  Jihoon JANG ,  Sungsu LIM ,  Younghee KIM ,  Yu Jin HWANG ,  Yong Seo CHO

IPC: A61K31/47 ,  A61K31/4709 ,  A61K31/5377

CPC classification number: A61K31/47 ,  A61K31/4709 ,  A61K31/5377

Abstract: The present disclosure relates to a quinoline derivative which inhibits the activity of histone methyltransferases (ESET/SETDB1) specific for the histone molecule H3K9 or a pharmaceutically acceptable salt thereof and a use thereof.