公开(公告)号：US20210356461A1

公开(公告)日：2021-11-18

申请号：US17284249

申请日：2019-10-10

Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

Inventor： Oh Seok KWON ,  Tae Joon KANG ,  Seon Joo PARK ,  Chul Soon PARK ,  Kyung Ho KIM ,  Jin Yeong KIM ,  Ji Yeon LEE ,  Chang Soo LEE

IPC: G01N33/543 ,  C07D235/06 ,  C07D403/12 ,  G01N33/553

Abstract: The present invention relates to a carbene compound having substituted at the terminal polyethylene glycol (PEG) having nitrogen-containing functional groups, a carbene-metal nanoparticle complex in which the carbene compound and metal nanoparticles are bounded, a preparation method thereof, and a biosensor using same.

公开(公告)号：US20210181147A1

公开(公告)日：2021-06-17

申请号：US16759432

申请日：2018-10-29

Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

Inventor： Oh Seok KWON ,  Chang Soo LEE ,  Seon Joo PARK ,  Tai Hwan HA ,  Chul Soon PARK ,  Kyung Ho KIM ,  Jin Yeong KIM

IPC: G01N27/414 ,  C01B32/194 ,  C01B32/186 ,  H01L51/00

Abstract: The present invention relates to a graphene transistor comprising: a substrate; a graphene channel layer arranged on the substrate; a pair of metals spaced from each other and respectively arranged at opposite ends of the graphene channel layer; and a linker layer arranged on the graphene channel layer and including an N-heterocyclic carbene compound, a fabrication method therefor, and a biosensor comprising the same. The graphene transistor according to the present invention in which the carbene group of the N-heterocyclic carbene compound forms a covalent bond with the graphene channel layer to modify the whole surface of the graphene channel layer exhibits excellent electric conductivity as a transistor and a biosensor comprising the transistor is improved in selectivity and sensitivity.