公开(公告)号：US20210356461A1

公开(公告)日：2021-11-18

申请号：US17284249

申请日：2019-10-10

Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

Inventor： Oh Seok KWON ,  Tae Joon KANG ,  Seon Joo PARK ,  Chul Soon PARK ,  Kyung Ho KIM ,  Jin Yeong KIM ,  Ji Yeon LEE ,  Chang Soo LEE

IPC: G01N33/543 ,  C07D235/06 ,  C07D403/12 ,  G01N33/553

Abstract: The present invention relates to a carbene compound having substituted at the terminal polyethylene glycol (PEG) having nitrogen-containing functional groups, a carbene-metal nanoparticle complex in which the carbene compound and metal nanoparticles are bounded, a preparation method thereof, and a biosensor using same.

公开(公告)号：US20230305028A1

公开(公告)日：2023-09-28

申请号：US18015189

申请日：2021-05-14

Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

Inventor： Eun Kyung LIM ,  Soo Jin JANG ,  Seong Uk SON ,  Byung Hoon KANG ,  Tae Joon KANG ,  Kyu Sun LEE ,  Ju Yeon JUNG

IPC: G01N33/94 ,  C08L49/00 ,  C07D237/04 ,  G01N21/78

CPC classification number: G01N33/94 ,  C07D237/04 ,  C08L49/00 ,  G01N21/78 ,  G01N2800/307

Abstract: The present disclosure provides a reagent composition for detecting illicit drugs, the composition comprising: a diacetylene derivative compound represented by chemical formula 1; and at least one compound selected from among gabazine (SR-95531), an amine group-linked diacetylene derivative represented by chemical formula 2-1, and a gabazine-linked diacetylene derivative represented by chemical formula 2-2.

公开(公告)号：US20240002934A1

公开(公告)日：2024-01-04

申请号：US18037222

申请日：2021-11-03

Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

Inventor： Eun Kyung LIM ,  Jae Woo LIM ,  Byung Hoon KANG ,  Tae Joon KANG ,  Seung Beom SEO ,  Soo Jin JANG ,  Ju Yeon JUNG

IPC: C12Q1/6876 ,  C12Q1/6806

CPC classification number: C12Q1/6876 ,  C12Q1/6806

Abstract: The present invention relates to a technology for analyzing and detecting/diagnosing a target nucleic acid. When the detection system according to the present invention is used, effective real-time detection or diagnosis efficiency can be obtained while problems such as noise are minimized. In particular, since, by using a house-keeping gene according to a method of use, the expression difference of the target nucleic acid can be corrected, and direct real-time target nucleic acid detection is possible, it can be effectively used for detecting various nucleic acids and diagnosing various diseases thereby.

公开(公告)号：US20230235382A1

公开(公告)日：2023-07-27

申请号：US18163936

申请日：2023-02-03

Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY ,  BIONANO HEALTH GUARD RESEARCH CENTER

Inventor： Tae Joon KANG ,  Jeong Moon ,  Ju Yeon Jung ,  Kyu Sun Lee ,  Eun Kyung Lim ,  Hong Ki Kim ,  Hyun Ju Kang

IPC: C12Q1/6834 ,  C12Q1/70

CPC classification number: C12Q1/6834 ,  C12Q1/70 ,  C12Q2600/112

Abstract: The present invention provides a target RNA detection method based on a dCas9/gRNA complex. A target RNA detection method according to the present invention can detect target RNA with the naked eye and without separate gene isolation and amplification steps, and, in particular, can rapidly and accurately detect target RNA through excellent target specificity and rapidity, and thus can exhibit excellent effects on the detection of various pathogens and/or viruses.