公开(公告)号：US20220105188A1

公开(公告)日：2022-04-07

申请号：US17429321

申请日：2020-02-07

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY ,  KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

Inventor： Jong Yeon HWANG ,  Jae Du HA ,  Sung Yun CHO ,  Pilho KIM ,  Chang Soo YUN ,  Hyun Jin KIM ,  Sung Goo PARK ,  Byoung Chul PARK ,  Jeong Hoon KIM ,  Sunhong KIM

IPC: A61K47/55 ,  A61K47/54

Abstract: The present invention relates to a target protein degradation-inducing Degraducer, a preparation method thereof, and a pharmaceutical composition for preventing or treating diseases related to EED, EZH2, or PRC2 comprising same as an active ingredient. A novel compound represented by formula 1, according to the present invention is a Degraducer compound that induces degradation of a target protein, i.e., EED or PRC2, utilizing cereblon E3 ubiquitin ligase, VHL E3 ubiquitin ligase, MDM2 E3 ubiquitin ligase, and cIAP E3 ubiquitin ligase, wherein the compound has an aspect of remarkably achieving target protein degradation-inducing activity through a ubiquitin proteasome system (UPS), and therefore there is a useful effect in that it is possible to provide a pharmaceutical composition for preventing or treating diseases or conditions related to a target protein, and a functional health food composition for preventing or improving same, comprising said compound as an active ingredient.

公开(公告)号：US20180272274A1

公开(公告)日：2018-09-27

申请号：US15920962

申请日：2018-03-14

Applicant: Korea Research Institute of Chemical Technology

Inventor： Jeong Hoon KIM ,  Su Young MOON ,  Bong Jun CHANG

IPC: B01D53/22 ,  B01D71/02 ,  B01D69/12 ,  B01D71/68 ,  B01D71/60 ,  B01D67/00 ,  B01D71/12 ,  C07C7/144

CPC classification number: B01D53/228 ,  B01D67/0079 ,  B01D67/0088 ,  B01D69/02 ,  B01D69/12 ,  B01D69/148 ,  B01D71/022 ,  B01D71/12 ,  B01D71/60 ,  B01D71/68 ,  B01D2256/24 ,  B01D2257/7022 ,  B01D2323/30 ,  B01D2325/14 ,  B01D2325/16 ,  C07C7/144 ,  C07C9/06 ,  C07C11/04 ,  C07C11/06 ,  C07C9/08 ,  C07C11/08 ,  C07C9/10

Abstract: A separation membrane for olefin separation and olefin separation method using the same are provided.

公开(公告)号：US20220168688A1

公开(公告)日：2022-06-02

申请号：US17495701

申请日：2021-10-06

Applicant: Korea Research Institute of Chemical Technology

Inventor： Jeong Hoon KIM ,  Jong Yeol JEON ,  Bo Ryoung PARK ,  Ho Cheol KANG

IPC: B01D53/22 ,  B01D5/00 ,  B01D53/00 ,  B01D53/047

Abstract: The present invention relates to a separation and recovery system and method of hydrogen from a coke oven gas (COG) in a steel industry, and more particularly, to a separation and recovery system and method of hydrogen from a coke oven gas (COG) in a steel industry, the system including a pre-processing unit removing impurities including tar, moisture, oil, hydrogen sulfide, and dusts from the coke oven gas (COG), a membrane separation unit including a polymer separation membrane module to generate a hydrogen concentrated gas stream by membrane-separating the coke oven gas (COG) processed in the pre-processing unit, and an adsorption unit separate and recover the hydrogen by allowing the hydrogen concentrated gas stream to contact an absorbent.

公开(公告)号：US20200306689A1

公开(公告)日：2020-10-01

申请号：US16827560

申请日：2020-03-23

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Jeong Hoon KIM ,  Chang In KONG ,  Yang No YUN ,  Su Young MOON ,  Bong Jun CHANG ,  Bo Ryoung PARK ,  Youn-Sang BAE ,  Tea-Hoon KIM

IPC: B01D53/22 ,  B01D71/00 ,  B01D67/00 ,  B01D69/12

Abstract: Provided are a methane-selective composite membrane comprising: a UiO-66 type organic-inorganic composite nanoporous material, a MIL-100 type organic-inorganic composite nanoporous material, or a ZIF-8 type organic-inorganic composite nanoporous material to which a methane-selective functional group is introduced for selectively separating methane from a gas mixture containing methane/nitrogen, a use thereof, and a method of preparing the same.

公开(公告)号：US20240018123A1

公开(公告)日：2024-01-18

申请号：US18017997

申请日：2021-07-28

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY ,  KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY ,  UBIX THERAPEUTICS, INC.

Inventor： Jong Yeon HWANG ,  Jae Du HA ,  Hyun Jin KIM ,  Sung Yun CHO ,  Pilho KIM ,  Chong Ock LEE ,  Jeong Hoon KIM ,  Byoung Chul PARK ,  Sung Goo PARK ,  Sunhong KIM ,  Yuri CHOI ,  Yaejin WOO ,  Song Hee LEE ,  Je Ho RYU ,  Jungmin AHN ,  Ji Youn PARK ,  Onnuri BAE ,  Hanwool KIM

IPC: C07D401/14 ,  C07D295/155 ,  C07D211/26

CPC classification number: C07D401/14 ,  C07D211/26 ,  C07D295/155

Abstract: The present disclosure provides a compound of a chemical structure having the ability of inhibiting or disintegrating an androgen receptor (AR), or a pharmaceutically acceptable salt of the compound. The present disclosure also provides a composition comprising such a compound or a pharmaceutically acceptable salt thereof. The present disclosure provides a pharmaceutical use of a compound according to the present disclosure, a salt thereof, and a composition comprising same for the treatment or prevention of AR-related diseases. The present disclosure also provides a method for treating or preventing AR-related diseases, comprising administering to a subject in need of treatment an effective amount of a compound according to the present disclosure, a salt thereof, or a composition comprising same.

公开(公告)号：US20230132426A1

公开(公告)日：2023-05-04

申请号：US17972127

申请日：2022-10-24

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Jeong Hoon KIM ,  Bo Ryoung PARK ,  Ho Cheol KANG

IPC: B01D53/22 ,  B01D53/04 ,  B01D53/047 ,  B01D51/10 ,  B01D71/68

Abstract: The present invention relates to a system and method for separating and recovering hydrogen from coke oven gas (COG) in steel industry, particularly a system and method for separating and recovering hydrogen at a concentration of 99.9% by volume or more from coke oven gas (COG) in steel industry with a recovery rate of 95% or more.

公开(公告)号：US20150217225A1

公开(公告)日：2015-08-06

申请号：US14687353

申请日：2015-04-15

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Jeong Hoon KIM ,  Hee Moon PARK ,  Bong Jun CHANG ,  Mihye YI ,  Eun-Hee KIM ,  Chae Young PARK

IPC: B01D53/22 ,  B01D71/64 ,  B29C47/00 ,  B01D69/08

CPC classification number: B01D53/228 ,  B01D67/0016 ,  B01D69/02 ,  B01D69/087 ,  B01D71/64 ,  B01D2053/224 ,  B01D2256/245 ,  B01D2257/504 ,  B01D2325/023 ,  B29C47/0014 ,  B29C47/0021 ,  B29C47/364 ,  B29C47/56 ,  B29C47/68 ,  B29K2079/085 ,  B29L2023/001 ,  Y02C10/10 ,  Y02P70/26

Abstract: The present invention relates to a polyimide-based macromolecular compound which is produced by using DOCDA and one or more diamines selected from the group consisting of MDA, ODA, PDA, TDA, TrMPD, TeMPD and MBCA; and a gas-separation asymmetrical hollow-fibre membrane comprising the same. The polyimide-based macromolecular compound according to the present invention can advantageously be used in the production of a gas-separation hollow-fibre membrane having an asymmetrical structure since the said compound is highly viscous due to a high molecular weight in addition to having outstanding gas permeability and high selectivity while having excellent high heat resistance, chemical resistance, and mechanical properties and being outstandingly soluble in polar organic solvents.

Abstract translation: 本发明涉及通过使用DOCDA和一种或多种选自MDA，ODA，PDA，TDA，TrMPD，TeMPD和MBCA的二胺生产的聚酰亚胺基高分子化合物。 以及包含该中空纤维膜的气体分离不对称中空纤维膜。 根据本发明的聚酰亚胺基高分子化合物可以有利地用于生产具有不对称结构的气体分离中空纤维膜，因为除了具有优异的气体之外，所述化合物由于高分子量而高度粘稠 渗透性和高选择性，同时具有优异的高耐热性，耐化学性和机械性能，并且极好地溶于极性有机溶剂。