Tubular fiber membrane for material exchange and method of making same

    公开(公告)号:US12220663B2

    公开(公告)日:2025-02-11

    申请号:US17257903

    申请日:2019-07-30

    Abstract: The invention relates to a method for producing a device for material exchange between two mediums, in which at least one mat of semipermeable hollow fibres (3) is wound onto a winding core (2), which has at least one core opening (2a) in its outer surface for a first in- or out-flowing medium, and the winding core (2) is arranged in an axially extending housing (1) having at least one housing opening (1a) for the first in- or out-flowing medium, and the axial end regions of the housing (1) are sealed by an adhesive (4) arranged around the hollow fibres (3), wherein at least one chamber region (5) surrounding the hollow fibres (3) is formed via the adhesion between the axial end regions (1b, 1c) of the housing (1) and between the winding core (2) and the housing (1), through which chamber region the first medium can flow via the core opening (2a) and the housing opening (1a), wherein the axial distance between the core opening (2a) and the housing opening (1a) is adjusted to a desired value of multiple possible values via the axial shifting of the winding core (2) relative to the hollow fibre winding (3) arranged around the winding core (2) and relative to the housing (1), and the hollow fibres (3) are adhered to the side of the housing (1) near to the housing opening (1a) in a region between the axial end surface of the housing and the housing opening (1a), and the hollow fibres (3) are adhered to the side of the housing (1) near to the core opening (2a) in a region between the axial end surface of the housing and the core opening (2a). The invention also relates to a number of multiple devices for material exchange between two mediums, wherein all devices comprise at least identical housings (1) and winding cores (2) that are identical at least in regions.

    Hydrophilic membranes with a non-ionic surfactant
    10.
    发明授权
    Hydrophilic membranes with a non-ionic surfactant 有权
    亲水膜与非离子表面活性剂

    公开(公告)号:US08528744B2

    公开(公告)日:2013-09-10

    申请号:US12680531

    申请日:2008-09-26

    CPC classification number: B01D69/02 A61M1/16 A61M1/3496 B01D67/0088

    Abstract: The invention relates to hydrophilic membranes which are supplemented or treated with a non-ionic surfactant and processes for preparing such membranes. The membranes are particularly suitable for plasma separation or for haemodialysis and haemodiafiltration, but can also advantageously be used in other applications. Accordingly, the invention is further directed to the use of such membranes for plasma separation, plasma filtration, micro filtration, plasma therapy, haemodialysis and haemodiafiltration or cell filtration applications, respectively. The treated hydrophilic membranes show excellent biocompatibility, such as reduced platelet drop and decreased TAT levels.

    Abstract translation: 本发明涉及用非离子表面活性剂补充或处理的亲水膜及其制备方法。 该膜特别适用于血浆分离或用于血液透析和血液透析过滤,但也可有利地用于其它应用。 因此,本发明进一步涉及这种膜用于血浆分离,血浆过滤,微过滤,血浆治疗,血液透析和血液透析或细胞过滤应用。 经处理的亲水膜显示出优异的生物相容性,例如减少血小板降低和降低的TAT水平。

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