公开(公告)号：US20240376443A1

公开(公告)日：2024-11-14

申请号：US18288490

申请日：2022-04-15

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Jee Won LEE ,  Yeon Hwa YU ,  Yoo Bin CHOI

IPC: C12N9/02 ,  C07K14/47 ,  C12P7/04

Abstract: The present invention relates to a protein including self-assembled ferritin monomers, in which a methane oxidation active domain, and an electron transfer domain including a flavin adenine dinucleotide (FAD)-binding domain are fused, and to: a protein which can oxidize methane by using NADH in vivo as a reducing agent, thus being capable of oxidizing methane to methanol without using a separate reducing agent; a microorganism expressing the same; a composition for producing methanol by using the same; and a method for producing methanol.

公开(公告)号：US20240209327A1

公开(公告)日：2024-06-27

申请号：US18288728

申请日：2022-04-15

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Jee Won LEE ,  Yeon Hwa YU ,  Yoo Bin CHOI

IPC: C12N9/02 ,  C07K14/47 ,  C12P7/04 ,  C12P7/16

CPC classification number: C12N9/0073 ,  C07K14/47 ,  C12N9/0083 ,  C12P7/04 ,  C12P7/16 ,  C12Y114/99039

Abstract: The present invention relates to: a protein having activity for producing methanol or butanol by oxidizing methane or butanol; a microorganism expressing same; a composition for producing methanol or butanol using same; and a method for producing methanol or butanol, wherein the protein is a self-assembled protein comprising a ferritin monomer fused with an ammonia oxidase active domain having methane oxidation activity, or a butane oxidase active domain having butane oxidation activity.