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    HUMAN INSULIN AND ANALOG CONJUGATE THEREOF
    1.
    发明申请
    HUMAN INSULIN AND ANALOG CONJUGATE THEREOF 审中-公开
    人类胰岛素和类似物

    公开(公告)号：US20140057841A1

    公开(公告)日：2014-02-27

    申请号：US14005538

    申请日：2012-03-19

    申请人： Kai Fan ,  Yu Cao ,  Yong Chen ,  Hongliang Li ,  Hairong Chen ,  Ying Wan

    发明人： Kai Fan ,  Yu Cao ,  Yong Chen ,  Hongliang Li ,  Hairong Chen ,  Ying Wan

    IPC分类号： C07K14/62

    CPC分类号： C07K14/62 ,  A61K38/28 ,  A61K47/60

    摘要： Disclosed is a recombinant human insulin or analog conjugate thereof. Said conjugate is formed by connecting the ε-amino group of lysine 29 of the B chain to activated polyethylene glycol by means of an amide bond. Further disclosed is a method of preparing said conjugate, a pharmaceutical compound, and a use for said conjugate in preparing medication for treating Type 1 and Type 2 diabetes.

    摘要翻译： 公开了一种重组人胰岛素或其类似物缀合物。 通过将B链的赖氨酸29的ε-氨基通过酰胺键连接到活化的聚乙二醇而形成所述缀合物。 进一步公开的是制备所述缀合物，药物化合物的方法，以及用于制备用于治疗1型和2型糖尿病的药物的所述缀合物的用途。

    Electrical switching apparatus including an adjustable damper assembly
    2.
    发明授权
    Electrical switching apparatus including an adjustable damper assembly 有权
    电气开关装置，包括可调节的阻尼器组件

    公开(公告)号：US09595404B2

    公开(公告)日：2017-03-14

    申请号：US14905984

    申请日：2013-07-19

    申请人： Fangwei Zheng ,  Hairong Chen ,  Hao Wu ,  Zongfeng Ye ,  GENERAL ELECTRIC COMPANY

    发明人： Fangwei Zheng ,  Hairong Chen ,  Hao Wu ,  Zongfeng Ye

    IPC分类号： H01H33/66 ,  H01H3/60 ,  H01H33/662

    CPC分类号： H01H3/605 ,  H01H33/66 ,  H01H33/66207

    摘要： An electrical switching apparatus including a housing, a circuit interrupter mechanism movably disposed in the housing, and a damper assembly. The damper assembly includes a bracket that secures the damper assembly to the housing. A damper body is adjustably secured to the bracket. A stopper is coupled to the damper body and arranged to limit relative movement of the circuit interrupter mechanism with respect to the damper assembly. A damper rod extends through an opening in the stopper and has a surface that is arranged to interact with the circuit interrupter mechanism. The damper rod is arranged to damp movement of the circuit interrupter mechanism with respect to the damper body when the circuit interrupter mechanism is in contact with the surface of the damper rod.

    摘要翻译： 一种电气开关装置，包括壳体，可移动地设置在壳体中的电路断续器机构和阻尼器组件。 阻尼器组件包括将阻尼器组件固定到壳体的支架。 阻尼器主体可调节地固定到支架上。 止动器联接到阻尼器主体并且布置成限制电路断续器机构相对于阻尼器组件的相对运动。 阻尼杆延伸穿过止动件中的开口并且具有布置成与断路器机构相互作用的表面。 阻尼杆设置成当电路断续器机构与阻尼杆的表面接触时，阻尼断路器机构相对于阻尼器主体的运动。