公开(公告)号：US20100034779A1

公开(公告)日：2010-02-11

申请号：US12092547

申请日：2006-11-02

申请人： Kaomei Guan ,  Gerd Hasenfuss ,  Karim Nayernia ,  Wolfgang Engel

发明人： Kaomei Guan ,  Gerd Hasenfuss ,  Karim Nayernia ,  Wolfgang Engel

IPC分类号： A61K45/00 ,  C12N5/073 ,  C12N5/071 ,  A01N1/00 ,  A61P25/28 ,  A61P5/00

CPC分类号： C12N5/0606 ,  C12N5/0611 ,  C12N2502/13 ,  C12N2506/02 ,  C12N2506/04

摘要： The present application describes a method of producing embryonic stem cell (ESC)-like cells derived from adult mammalian testis. Furthermore, the application describes to a method of producing embryoid bodies from ESC-like cells as well as a method of producing a tissue and/or a differentiated cell from the ESC-like cell or the embryoid body. In addition, an ESC-like cell, an embryoid body and/or differentiated cell and/or tissue obtainable by said methods and pharmaceutical preparations containing the same are provided. Finally, the application describes to the use of these products for medical treatments and the preparation of pharmaceutical compositions for medical treatments.

摘要翻译： 本申请描述了由成年哺乳动物睾丸产生的胚胎干细胞（ESC）样细胞的方法。 此外，本申请描述了从ESC样细胞产生胚状体的方法以及从ESC样细胞或类胚体产生组织和/或分化细胞的方法。 另外，提供了可以通过所述方法获得的ESC样细胞，类胚体和/或分化细胞和/或组织以及含有它们的药物制剂。 最后，本申请描述了这些产品用于医疗治疗和制备用于医疗治疗的药物组合物。