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公开(公告)号:US20130164327A1
公开(公告)日:2013-06-27
申请号:US13643788
申请日:2011-04-28
IPC分类号: C12N7/00
CPC分类号: C12N7/00 , A61K39/00 , A61K2039/5256 , A61K2039/545 , A61K2039/55 , C07K14/005 , C12N15/86 , C12N2710/10322 , C12N2710/10343 , C12N2710/10362
摘要: The invention relates to recombinant adenovirus displaying one or more heterologous epitope(s) on their fiber protein. These recombinant adenovirus are useful as vaccines for generating an immune response against said epitope(s) in individuals having a pre-existing anti-Ad immunity.
摘要翻译: 本发明涉及在其纤维蛋白上显示一个或多个异源表位的重组腺病毒。 这些重组腺病毒可用作在具有预先存在的抗Ad免疫的个体中产生针对所述表位的免疫应答的疫苗。
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公开(公告)号:US09862931B2
公开(公告)日:2018-01-09
申请号:US13643788
申请日:2011-04-28
IPC分类号: C12N7/00 , C07K14/005 , A61K39/235 , A61K39/00 , C12N15/86
CPC分类号: C12N7/00 , A61K39/00 , A61K2039/5256 , A61K2039/545 , A61K2039/55 , C07K14/005 , C12N15/86 , C12N2710/10322 , C12N2710/10343 , C12N2710/10362
摘要: The invention relates to recombinant adenovirus displaying one or more heterologous epitope(s) on their fiber protein. These recombinant adenovirus are useful as vaccines for generating an immune response against said epitope(s) in individuals having a pre-existing anti-Ad immunity.
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