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12 条记录 (耗时 0.019 秒)

    Means for guiding rails longitudinally free of play
    3.
    发明授权
    Means for guiding rails longitudinally free of play 失效
    用于纵向引导导轨的装置无法播放

    公开(公告)号：US5582381A

    公开(公告)日：1996-12-10

    申请号：US441202

    申请日：1995-05-15

    申请人： Werner Graf ,  Simon Frank ,  Karl Baumann

    发明人： Werner Graf ,  Simon Frank ,  Karl Baumann

    IPC分类号： B60N2/07 ,  F16C29/12 ,  F16M13/00

    CPC分类号： F16C29/02 ,  B60N2/071 ,  B60N2/0715 ,  B60N2/072 ,  B60N2/075 ,  B60N2205/20

    摘要： Play-free longitudinal guiding means having rails than run inside each other, namely a lower rail and an upper rail that can be displaced in a sliding manner with respect to the lower rail, for securing seats in vehicles such as private cars. The play-free longitudinal guiding means is such that the lower rail features along its length wall parts that have the shape of alignment grooves, and the upper rail features wall parts which run parallel to the wall parts of the lower rail and are shaped into an alignment groove, and the alignment grooves of the upper and lower rails face each other and form a sliding alignment channel. In the sliding channel there are sliding elements which in the free-standing condition exhibit a larger cross-section than in the installed condition, and the sliding elements guide the lower and upper rails without any play.

    摘要翻译： 具有比彼此相对运行的轨道的无游隙的纵向引导装置，即可以相对于下轨道滑动地移位的下轨道和上轨道，用于将座椅固定在诸如私家车辆的车辆中。 无轨道纵向引导装置使得下轨道沿其长度壁部分具有对准凹槽的形状，并且上轨道具有平行于下轨道的壁部分延伸并且成形为 上下导轨的对准槽彼此面对并形成滑动对准通道。 在滑动通道中，存在滑动元件，其在独立状态下表现出比在安装状态下更大的横截面，并且滑动元件引导下轨道和上轨而没有任何游隙。

    3,5-dimethyl-4-methoxypyridine derivatives
    4.
    发明授权
    3,5-dimethyl-4-methoxypyridine derivatives 失效
    3,5-二甲基-4-甲氧基吡啶衍生物

    公开(公告)号：US5066810A

    公开(公告)日：1991-11-19

    申请号：US432874

    申请日：1989-11-07

    申请人： Karl Baumann

    发明人： Karl Baumann

    IPC分类号： C07D213/68

    CPC分类号： C07D213/68

    摘要： A process for the preparation of compounds of formula I ##STR1## in which X is the radical OH or Cl, by the catalytic hydrogenation of 3,5-dimethyl-4-methoxy-2-cyanopyridine, subsequent reaction of the resulting 3,5-dimethyl-4-methoxy-2-aminomethylpyridine to give 3,5-dimethyl-4-methoxy-2-hydroxymethylpyridine and, if desired, chlorination to give 3,5-dimethyl-4-methoxy-2-chloromethylpyridine, and the novel intermediate 3,5-dimethyl-4-methoxy-2-aminomethylpyridine.

    摘要翻译： 通过3,5-二甲基-4-甲氧基-2-氰基吡啶的催化氢化制备式I化合物I的方法，其中X是自由基OH或Cl，随后将所得的3， 5-二甲基-4-甲氧基-2-氨基甲基吡啶，得到3,5-二甲基-4-甲氧基-2-羟甲基吡啶，如果需要，进行氯化，得到3,5-二甲基-4-甲氧基-2-氯甲基吡啶， 新型中间体3,5-二甲基-4-甲氧基-2-氨基甲基吡啶。

    Substituted 4-pyridone 3-carboxylic acid derivatives, method for their production and their pharmaceutical compositions
    5.
    发明授权
    Substituted 4-pyridone 3-carboxylic acid derivatives, method for their production and their pharmaceutical compositions 失效
    取代的4-吡啶酮3-羧酸衍生物，其制备方法及其药物组合物

    公开(公告)号：US5045549A

    公开(公告)日：1991-09-03

    申请号：US70351

    申请日：1987-07-06

    申请人： Fritz Sauter ,  Ulrich Jordis ,  Manfred Rudolf ,  Josef Wieser ,  Karl Baumann

    发明人： Fritz Sauter ,  Ulrich Jordis ,  Manfred Rudolf ,  Josef Wieser ,  Karl Baumann

    IPC分类号： C07D487/18 ,  A61K31/40 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/495 ,  A61K31/55 ,  A61P31/04 ,  C07D487/08 ,  C07D519/00

    CPC分类号： C07D487/08

    摘要： New 4-Pyridone derivatives of General Formula are claimed ##STR1## in which R.sub.1 is methylamino,4-fluorophenyl, 2,4-difluorophenyl, R.sub.2 is hydrogen or a sulfur atom that is joined to the ring nitrogen by an ethylene bride, X is a hydrogen or a physiologically removable ester group and Y is a base of the general formula ##STR2## In formula IIa and IIb, R.sub.3 is hydrogen, lower alkyl, benzyl, formyl, acetonyl or a moiety of the formula ##STR3## Also claimed are the addition salts of compounds of formula I with pharmaceutically acceptable inorganic or organic acids or base and/or their hydrates. Also claimed are the methods of manufacture of compounds of formula I and their use as antibacterial agents.

    摘要翻译： 新的通式的4-吡啶酮衍生物要求保护其中R1是甲基氨基，4-氟苯基，2,4-二氟苯基，R2是氢或通过乙烯新娘连接到环氮的硫原子的（I） ，X是氢或生理上可除去的酯基，Y是通式为（IIa）或（IIb）或IIb的碱在式IIa和IIb中，R 3是氢，低级烷基，苄基，甲酰基， 丙酮基或下式的部分还要求保护的是式I化合物与药学上可接受的无机酸或有机酸或碱和/或其水合物的加成盐。 还要求的是制备式I化合物及其作为抗菌剂的用途的方法。

    Multiple holder for substrates to be treated
    6.
    发明授权
    Multiple holder for substrates to be treated 失效
    用于待处理基材的多个支架

    公开(公告)号：US4643128A

    公开(公告)日：1987-02-17

    申请号：US739568

    申请日：1985-05-30

    申请人： Bernhard Bracher ,  Karl Baumann ,  Hermann Staub

    发明人： Bernhard Bracher ,  Karl Baumann ,  Hermann Staub

    IPC分类号： G02B1/11 ,  C23C14/50 ,  G02B1/10 ,  G02C13/00 ,  B05C13/02

    CPC分类号： C23C14/50

    摘要： A multiple holder for substrates to be treated, particularly finish-ground spectacle lenses to be cleaned and then coated, comprises four arms 1a to 1d forming a rectangular cross. On their sides facing the four quadrants, the arms are provided with grooves for receiving the substrates 11 to be treated which substrates are forced by springs 4a to 4d to engage the grooves. The holder is used primarily for the secure holding and transportation of substrates during a sequence of treating operations.

    摘要翻译： 用于要处理的基底的多个保持器，特别是要被清洁并然后被涂覆的洁面眼镜片包括形成矩形十字的四个臂1a至1d。 在它们面向四个象限的两侧，臂设置有槽，用于接收待处理的基板11，这些基板被弹簧4a至4d迫使槽与槽接合。 保持器主要用于在一系列处理操作期间牢固地保持和输送基底。

    Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds
    7.
    发明申请
    Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds 审中-公开
    药用活性四氢吡咯嗪酮化合物

    公开(公告)号：US20080262070A1

    公开(公告)日：2008-10-23

    申请号：US12089254

    申请日：2006-10-04

    申请人： Karl Baumann

    发明人： Karl Baumann

    IPC分类号： A61K31/407 ,  C07D487/04

    CPC分类号： C07D487/04

    摘要： Tetrahydro-pyrrolizinone compounds which mediate the activity of LFA-1 with its ligands involved in cell adhesion, migration and activation.

    摘要翻译： 四氢吡咯嗪酮化合物，其介导LFA-1的活性，其配体涉及细胞粘附，迁移和活化。

    Process for the preparation of substituted 3-amino-2 (benzoyl)-acrylic acid esters, and a process for the preparation of intermediates for antibacterial active compounds from these compounds
    9.
    发明授权
    Process for the preparation of substituted 3-amino-2 (benzoyl)-acrylic acid esters, and a process for the preparation of intermediates for antibacterial active compounds from these compounds 失效
    取代的3-氨基-2（苯甲酰基） - 丙烯酸酯的制备方法，以及由这些化合物制备抗菌活性化合物的中间体的方法

    公开(公告)号：US5011971A

    公开(公告)日：1991-04-30

    申请号：US363198

    申请日：1989-06-08

    申请人： Karl Baumann ,  Klaus Fitzinger

    发明人： Karl Baumann ,  Klaus Fitzinger

    IPC分类号： C07C253/20 ,  C07C227/04 ,  C07C227/10 ,  C07C229/34 ,  C07C255/38 ,  C07C255/41 ,  C07D215/56

    CPC分类号： C07C227/04 ,  C07C255/41 ,  C07D215/56 ,  C07C2101/02

    摘要： Process for the preparation of substituted 3-amino-2-(benzoyl)-acrylic acid esters of the formula I ##STR1## in which R.sub.1 denotes an alkyl radical with 1 to 4 C atoms, X.sub.1 denotes halogen, in particular fluorine or chlorine, X.sub.2, X.sub.3, X.sub.4 and X.sub.5 denote hydrogen, halogen, in particular fluorine or chlorine, an alkyl radical having 1-4 C atoms or an alkoxy radical having 1-4 C atoms in the alkyl chain, by selectively reducing a substituted 2-cyano-3-hydroxy-3(phenyl)acrylic acid ester of the formula II ##STR2## in which R.sub.1, X.sub.1, X.sub.2, X.sub.3, X.sub.4 and X.sub.5 have the meaning given above, and a process for the preparation of intermediate products for antibacterially active compounds from these compounds.

    摘要翻译： 用于制备式I的取代的3-氨基-2-（苯甲酰基） - 丙烯酸酯的方法，其中R 1表示具有1至4个C原子的烷基，X 1表示卤素，特别是氟或氯 ，X2，X3，X4和X5表示氢，卤素，特别是氟或氯，具有1-4个碳原子的烷基或烷基链中具有1-4个碳原子的烷氧基，通过选择性还原取代的2- 其中R1，X1，X2，X3，X4和X5具有上述含义的式II的氰基-3-羟基-3（苯基）丙烯酸酯，以及制备中间产物的方法 来自这些化合物的抗菌活性化合物。

    Pharmaceutically Active Tetrahydro-Pyrrolo[1,2-B]Isothiazole 1,1-Dioxides
    10.
    发明申请
    Pharmaceutically Active Tetrahydro-Pyrrolo[1,2-B]Isothiazole 1,1-Dioxides 审中-公开
    药用活性四氢吡咯并[1,2-B]异噻唑1,1-二氧化物

    公开(公告)号：US20080242710A1

    公开(公告)日：2008-10-02

    申请号：US12089155

    申请日：2006-10-04

    申请人： Karl Baumann

    发明人： Karl Baumann

    IPC分类号： A61K31/429 ,  C07D513/04 ,  A61P29/00

    CPC分类号： A61K31/429 ,  C07D513/04 ,  Y02A50/401 ,  Y02A50/411

    摘要： 3a,4,5,6-Tetrahydro-pyrrolol,2-b]-isothiazoles wherein the sulphur is in the form of a dioxide and their use for the treatment or prevention of disorders mediated by interactions of LFA-1 with its ligands involved in cell adhesion, migration and activation.

    摘要翻译： 3a，4,5,6-四氢吡咯并，2-b] - 异噻唑，其中硫为二氧化物形式，以及它们用于治疗或预防由LFA-1与其涉及的配体相互作用介导的病症的用途 细胞粘附，迁移和活化。