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25 条记录 (耗时 0.027 秒)

    2-(cyclic amino)-pyrimidone derivatives
    3.
    发明授权
    2-(cyclic amino)-pyrimidone derivatives 失效
    2-（环状氨基） - 嘧啶酮衍生物

    公开(公告)号：US08569294B2

    公开(公告)日：2013-10-29

    申请号：US12282396

    申请日：2007-03-14

    申请人： Kenji Fukunaga ,  Toshiyuki Kohara ,  Kazutoshi Watanabe ,  Yoshihiro Usui ,  Fumiaki Uehara ,  Satoshi Yokoshima ,  Daiki Sakai ,  Shin-ichi Kusaka ,  Kazuki Nakayama

    发明人： Kenji Fukunaga ,  Toshiyuki Kohara ,  Kazutoshi Watanabe ,  Yoshihiro Usui ,  Fumiaki Uehara ,  Satoshi Yokoshima ,  Daiki Sakai ,  Shin-ichi Kusaka ,  Kazuki Nakayama

    IPC分类号： A61K31/535

    CPC分类号： C07D413/14 ,  C07D401/04 ,  C07D401/14 ,  C07D403/14 ,  C07D409/14 ,  C07D453/06 ,  C07D493/04

    摘要： A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutical acceptable salt thereof: wherein R2 represents a hydrogen or the like; R3 represents methyl group or the like; R20 represents a halogen atom or the like; q represents an integer of 0 to 3; Z represent nitrogen atom, CH, or the like; R4 represents hydrogen or the like; R5 represents hydrogen or the like; R6 represents a substituted alkyloxy and the like; p represents an integer of 0 to 3; X represents bond, CH2, oxygen atom, NH, or the like; any one or more of R5 and R6, R5 and R4, R6 and R4, X and R5, X and R4, X and R6, and R6 and R6 may combine to each other to form a ring, which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as a neurodegenerative diseases (e.g. Alzheimer disease).

    摘要翻译： 由式（I）表示的化合物或其光学活性异构体或其药学上可接受的盐：其中R2表示氢等; R3表示甲基等; R 20表示卤素原子等; q表示0〜3的整数， Z表示氮原子，CH等; R4表示氢等; R5表示氢等; R6表示取代的烷氧基等; p表示0〜3的整数， X表示键，CH2，氧原子，NH等; R 5和R 6，R 5和R 4，R 6和R 4，X和R 5，X和R 4，X和R 6以及R 6和R 6中的任何一个或多个可以彼此结合形成环，其用于预防和/ 或治疗由tau蛋白激酶1多动症如神经变性疾病（例如阿尔茨海默病）引起的疾病。

    Vacuum type circuit breaker
    5.
    发明授权
    Vacuum type circuit breaker 失效
    真空式断路器

    公开(公告)号：US4419553A

    公开(公告)日：1983-12-06

    申请号：US336433

    申请日：1981-12-31

    申请人： Masayuki Ohshita ,  Toshiaki Horiuchi ,  Takashi Yamanaka ,  Yoshihiro Usui

    发明人： Masayuki Ohshita ,  Toshiaki Horiuchi ,  Takashi Yamanaka ,  Yoshihiro Usui

    IPC分类号： H01H33/66 ,  H01H33/666 ,  H01H33/00

    CPC分类号： H01H33/666 ,  H01H2001/5827 ,  H01H2033/6667 ,  H01H33/668

    摘要： A vacuum type circuit breaker which has an operating lever (31) connected at one end thereof to the movable electrode (102) of a vacuum switch tube (1) and at the other end to a closing spring (55) through an energy storage link mechanism (54). The operating lever (31) functions to drive the movable electrode (102). The energy storage link mechanism (54) is provided with an energy storage crank (52) pivotally supported on a shaft (2051). The force which the energy storage link mechanism (54) applies to the operating lever (31) is set such that it is less than a force on the operating lever (31) which is produced by the difference between the internal pressure of the vacuum switch tube (1) and atmospheric pressure. This arrangement makes it possible, upon occurrence of vacuum loss, to detect the vacuum shortage, whereupon the closing of the switch is prevented to thereby avoid an accident due to vacuum degradation.

    摘要翻译： 一种真空式断路器，其具有在其一端连接到真空开关管（1）的可动电极（102）的操作杆（31），另一端通过能量存储连杆 机构（54）。 操作杆（31）用于驱动可动电极（102）。 能量存储连杆机构（54）设置有枢转地支撑在轴（2051）上的储能曲柄（52）。 能量存储连杆机构54施加到操作杆31的力被设定为小于由真空开关的内部压力之间的差异产生的操作杆（31）上的力 管（1）和大气压力。 这种布置使得在发生真空损失时可以检测真空不足，从而防止开关的闭合，从而避免由于真空劣化而引起的事故。

    Production process of non-flying plastic mircoballoons
    7.
    发明授权
    Production process of non-flying plastic mircoballoons 有权
    非飞行塑料微气球的生产工艺

    公开(公告)号：US06784215B2

    公开(公告)日：2004-08-31

    申请号：US09988145

    申请日：2001-11-19

    申请人： Yoshihiro Shigemori ,  Osamu Saito ,  Yoshihiro Usui

    发明人： Yoshihiro Shigemori ,  Osamu Saito ,  Yoshihiro Usui

    IPC分类号： C08J916

    CPC分类号： B01F17/0057 ,  B01F17/0021 ,  B01F17/0028 ,  B01F17/0064 ,  C08J9/22

    摘要： Non-flying plastic microballoons are produced by bringing unexpanded, expandable plastic microballoons, which have been heated to a temperature lower than an expansion starting temperature thereof, and a mixture of a wetting agent and gas, the mixture having been heated to a temperature at least equal to the expansion starting temperature of the expandable plastic microballoons, into contact with each other to cause expansion of the expandable plastic balloons, and then cooling the resulting expanded plastic balloons.

    摘要翻译： 通过将未膨胀的可膨胀塑料微球加热到低于其膨胀起始温度的温度和润湿剂和气体的混合物来制造非飞行塑料微球，该混合物已被加热到至少的温度 等于可膨胀塑料微球的膨胀起始温度彼此接触以引起可膨胀塑料球的膨胀，然后冷却所形成的膨胀塑料球。

    1,3-oxazin-4-one derivative, herbicide containing same, and intermediate for preparing same
    8.
    发明授权
    1,3-oxazin-4-one derivative, herbicide containing same, and intermediate for preparing same 失效
    1,3-恶嗪-4-酮衍生物，含有它们的除草剂及其制备中间体

    公开(公告)号：US5977025A

    公开(公告)日：1999-11-02

    申请号：US663118

    申请日：1996-06-20

    申请人： Keiichi Hayashizaki ,  Yoshihiro Usui ,  Koichi Araki ,  Norishige Toshima ,  Tetsuya Murata ,  Takako Aoki ,  Atsushi Go ,  Hideshi Mukaida ,  Rika Higurashi

    发明人： Keiichi Hayashizaki ,  Yoshihiro Usui ,  Koichi Araki ,  Norishige Toshima ,  Tetsuya Murata ,  Takako Aoki ,  Atsushi Go ,  Hideshi Mukaida ,  Rika Higurashi

    IPC分类号： A01N43/86 ,  A01P13/00 ,  C07C229/12 ,  C07C251/08 ,  C07D265/06 ,  A01N43/32

    CPC分类号： C07C251/08 ,  C07D265/06

    摘要： This invention provides 1,3-oxazin-4-one derivatives represented by following general formula (I): ##STR1## in which R.sup.1 represents a phenyl group which may be substituted; R.sup.2 represents a hydrogen atom or a lower alkyl group; R.sup.3 represents a hydrogen atom, a lower alkyl group, an aralkyl group or a phenyl group which may be substituted; R.sup.4 and R.sup.5 each independently represent a lower alkyl group; and W represents an oxygen atom or a group represented by the formula --N(R.sup.6)-- in which R.sup.6 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group or a lower alkynyl group. There are also provided herbicidal compositions containing the derivatives and intermediates for preparing them. The compounds according to the present invention exhibit strong herbicidal activities and thus they are useful as active ingredients of agricultural chemicals.

    摘要翻译： PCT No.PCT / JP94 / 02152 Sec。 371日期：1996年6月20日 102（e）1996年6月20日PCT 1994年12月20日PCT PCT。 WO95 / 18113 PCT出版物 日期：1995年7月6日本发明提供由以下通式（I）表示的1,3-恶嗪-4-酮衍生物：其中R1表示可被取代的苯基; R2表示氢原子或低级烷基; R3表示氢原子，低级烷基，芳烷基或可被取代的苯基; R4和R5各自独立地表示低级烷基; W表示氧原子或式-N（R6） - 表示的基团，其中R6表示氢原子，低级烷基，低级烯基或低级炔基。 还提供含有用于制备它们的衍生物和中间体的除草组合物。 根据本发明的化合物表现出强烈的除草活性，因此它们可用作农药的活性成分。

    Process for producing non-scattering hollow plastic balloons
    9.
    发明授权
    Process for producing non-scattering hollow plastic balloons 失效
    生产非散射中空塑料气球的方法

    公开(公告)号：US5753156A

    公开(公告)日：1998-05-19

    申请号：US675799

    申请日：1996-07-05

    申请人： Yoshihiro Shigemori ,  Osamu Saito ,  Yoshihiro Usui

    发明人： Yoshihiro Shigemori ,  Osamu Saito ,  Yoshihiro Usui

    IPC分类号： B01J13/02 ,  C08J9/22

    CPC分类号： B01J13/02

    摘要： A process for producing non-scattering hollow plastic balloons which comprises: (a) heating a mixture (A) of non-foamed plastic balloons and a first wetting agent, which is a plasticizer, to a temperature from 40.degree. C. to a temperature which is 40.degree. C. below an exit temperature of a heat exchanger, (b) contacting the mixture (A) with a second wetting agent being heated to a temperature equal to or above the foaming starting temperature of the non-foamed plastic balloons, wherein a ratio of the mixture (A) to the second wetting agent (B) is 1:0.5 to 1:1.5, the contacting being within 1 minute after heating the mixture (A) by the heat exchanger to a temperature ranging from 20.degree. to 50.degree. C. below the foaming starting temperature of the non-foamed plastic balloons, (c) foaming the non-foamed plastic balloons, and (d) cooling the resultant mixture from step (c) containing the foamed plastic balloons. Non-scattering foamed plastic balloons can thus be obtained simultaneously with the foaming. The present process needs a smaller amount of a plasticizer than the conventional process of wetting foamed plastic balloons with a plasticizer.

    摘要翻译： 一种制造非散射中空塑料球的方法，包括：（a）将非发泡塑料球的混合物（A）和作为增塑剂的第一润湿剂加热至40℃至 其在热交换器的出口温度以下为40℃，（b）使混合物（A）与加热至等于或高于非泡沫塑料气囊的起泡温度的温度的第二润湿剂接触， 其中混合物（A）与第二润湿剂（B）的比例为1:0.5至1:1.5，接触在通过热交换器将混合物（A）加热至20℃之后的1分钟内 至低于非发泡塑料球泡的发泡起始温度至50℃，（c）使非发泡塑料球泡沫发泡，和（d）从含有发泡塑料球的步骤（c）中冷却得到的混合物。 因此，可以与发泡同时获得非散射的泡沫塑料气囊。 与使用增塑剂润湿发泡塑料球的常规方法相比，本方法需要更少量的增塑剂。

    Synergistic herbicidal compositions comprising 1,3-oxazin-4-one compounds
    10.
    发明授权
    Synergistic herbicidal compositions comprising 1,3-oxazin-4-one compounds 失效
    包含1,3-恶嗪-4-酮化合物的协同除草组合物

    公开(公告)号：US5672566A

    公开(公告)日：1997-09-30

    申请号：US583073

    申请日：1996-02-05

    申请人： Kazuo Jikihara ,  Hisato Suzuki ,  Yumiko Miyashita ,  Toshishiro Maruyama ,  Yoshihiro Usui ,  Futaba Makimura ,  Jiro Morishige

    发明人： Kazuo Jikihara ,  Hisato Suzuki ,  Yumiko Miyashita ,  Toshishiro Maruyama ,  Yoshihiro Usui ,  Futaba Makimura ,  Jiro Morishige

    IPC分类号： A01N43/86

    CPC分类号： A01N43/86

    摘要： A herbicidal composition containing as active ingredients the following two components, (A): at least one of 1,3-oxazin-4-one derivatives represented by the following general formula (I) ##STR1## wherein, R is a methyl or an ethyl group, Y is a halogen atom, a lower haloalkyl or a lower haloalkoxy group, and n is 0, 1, 2 or 3, and (B): at least one compound selected from certain known herbicides. It is possible, by use of this composition, to completely control annual gramineous weeds, annual broad-leaved weeds and perennial weeds, without causing any phytotoxicity on agriculturally important crops at a low dose of the active ingredients.

    摘要翻译： PCT No.PCT / JP94 / 01133 Sec。 371日期：1996年2月5日 102（e）日期1996年2月5日PCT提交1994年7月12日PCT公布。 公开号WO95 / 02329 日期1995年1月26日一种除草组合物，其含有以下两种成分作为活性成分：（A）：由以下通式（I）表示的1,3-恶嗪-4-酮衍生物中的至少一种： 其中，R为甲基或乙基，Y为卤素原子，低级卤代烷基或低级卤代烷氧基，n为0,1,2或3，（B）：选自某些已知的至少一种化合物 除草剂。 通过使用这种组合物，可以完全控制一年生禾本科杂草，一年生阔叶杂草和多年生杂草，而不会在低剂量活性成分下对农业重要作物造成任何植物毒性。