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1.发明授权Solid tissue impedance estimating method, cardiac output calculating method, pulmonary artery wedge pressure calculating method, cardiac output monitoring device, cardiac output monitoring system, pulmonary artery wedge pressure monitoring device, and pulmonary artery wedge pressure monitoring system 有权固体组织阻抗估计方法，心输出量计算方法，肺动脉楔压计算方法，心输出量监测装置，心输出量监测系统，肺动脉楔压监测装置和肺动脉楔压监测系统公开(公告)号：US08262581B2
公开(公告)日：2012-09-11
申请号：US11950169
申请日：2007-12-04
IPC分类号： A61B5/02
CPC分类号： A61B5/029 , A61B5/0295 , A61B5/053
摘要： A practical method for estimating cardiac output and pulmonary artery wedge pressure with good accuracy is provided. A method is provided for estimating the impedance arising from solid tissue by determining the impedance at the intersection between the line of identity and the extrapolated regression line, where the regression line is obtained by linearly regressing the maximum value to the minimum value of the impedance signal of each of multiple data sets, where each data set contains the maximum value and the minimum value of the impedance signal during one cardiac cycle, where impedance signal is obtained between a can electrode implanted in the left thoracic wall and an electrode inserted into the coronary vein, over a specific period of time following the infusion of hypertonic saline into the pulmonary circulation.
摘要翻译： 提供了一种准确估计心输出量和肺动脉楔形压力的实用方法。 提供了一种用于通过确定身份线与外推回归线之间的交叉点处的阻抗来估计由固体组织产生的阻抗的方法，其中回归线通过将最大值线性回归到阻抗信号的最小值而获得 其中每个数据集包含在一个心动周期期间的阻抗信号的最大值和最小值，其中在植入在左胸壁的罐电极和插入冠状动脉的电极之间获得阻抗信号 在输注高渗盐水进入肺循环后的特定时间段内静脉。
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2.发明申请SYSTEM FOR AUTOMATICALLY MINIMIZING CARDIAC OXYGEN CONSUMPTION AND CARDIAC DISEASE TREATING SYSTEM USING THE SAME 有权使用相同方法自动最小化心脏氧化消耗和心脏疾病治疗系统公开(公告)号：US20110098767A1
公开(公告)日：2011-04-28
申请号：US12279753
申请日：2007-02-16
IPC分类号： A61N1/365
CPC分类号： A61B5/0215 , A61B5/029 , A61B5/4866 , A61N1/36557
摘要： [PROBLEMS] A system for automatically minimizing cardiac oxygen consumption that is capable of estimating a patient's amount of cardiac oxygen consumption with high accuracy and moreover capable of minimizing the amount of cardiac oxygen consumption and a cardiac disease treating system are provided.[MEANS FOR SOLVING PROBLEMS] The cardiac disease treating system 10 comprises an input part 12 for inputting a patient's 20 indexes of kinetics of blood circulation including at least heart rate, a cardiac oxygen consumption calculation monitor unit 14 for calculating the estimated value of said patient's 20 amount of cardiac oxygen consumption based on the indexes of kinetics of blood circulation input from the input part 12, and a cardiac oxygen consumption curtailment unit 16 for comparing the heart rate input from the input part 12 and the critical heart rate minimizing the estimated value of amount of cardiac oxygen consumption calculated by the cardiac oxygen consumption monitor unit 14 and controlling the patient's 20 heart rate in conformity with the results of this comparison.
摘要翻译： [问题]提供一种用于自动最小化心脏氧消耗的系统，其能够以高精度估计患者的心脏耗氧量并且还能够最小化心脏氧消耗量和心脏疾病治疗系统。 解决问题的手段心脏病治疗系统10包括：输入部12，用于输入至少包括心率的患者的血液循环动力学20个指标;心脏耗氧量计算监测单元14，用于计算所述患者的心率的估计值; 基于从输入部分12输入的血液循环动力学指标的20个心脏耗氧量和用于比较从输入部分12输入的心率和将估计值最小化的临界心率的心脏耗氧量削减单元16 由心脏氧消耗监测单元14计算的心脏氧消耗量，并根据该比较的结果控制患者的20个心率。
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公开(公告)号：US20090221923A1
公开(公告)日：2009-09-03
申请号：US11719400
申请日：2004-11-18
IPC分类号： A61B5/029 , A61B5/0215
CPC分类号： A61M5/1723 , A61B5/02028 , A61B5/02158 , A61B5/029 , A61M5/14244 , A61M2230/30
摘要： Problems To provide a cardiac disease treatment system for accurately diagnosing the functional cause of an abnormality of a cardiac disease by analyzing the hemodynamic state of a patient, automatically performing medication in accordance with the diagnosis result, and treating the cardiac disease. Means for Solving Problems The cardiac disease treatment system is characterized by comprising input means (2) for inputting the cardiac output value of the patient, the left atrial pressure value and/or the right atrial pressure value, first calculating means (31) for calculating the pumping ability value of the left heart or the right heart from the inputted cardiac output and the left or right atrial pressure value, first comparing means (41) for comparing the pumping ability value of the left heart or the right heart with a target pumping ability value, and first medicating means (51) for medicating the patient in accordance with the result of the comparison by the first comparing means (41).
摘要翻译： 问题提供一种心脏疾病治疗系统，用于通过分析患者的血液动力学状态，根据诊断结果自动进行药物，以及治疗心脏病，来准确诊断心脏病异常的功能原因。 解决问题的手段心脏疾病治疗系统的特征在于包括输入装置（2），用于输入患者的心输出量值，左心房压力值和/或右心房压力值，第一计算装置（31），用于计算 来自输入的心输出量的左心脏或右心脏的泵送能力值和左心房或右心房压力值，用于将左心脏或右心脏的抽吸能力值与目标泵送的第一比较装置（41） 能力值，以及用于根据第一比较装置（41）的比较结果对患者进行治疗的第一药剂装置（51）。
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公开(公告)号：US08000791B2
公开(公告)日：2011-08-16
申请号：US12103011
申请日：2008-04-15
CPC分类号： A61N1/37288 , A61N1/368 , A61N1/37205 , A61N1/3756 , A61N1/3785 , H01M8/16 , Y02E60/527
摘要： A distributed cardiac pacing system comprises a first ultra miniature integrated cardiac pacemaker adapted to be placed in an atrial myocardium and a second ultra miniature integrated cardiac pacemaker adapted to be placed in a ventricular myocardium.
摘要翻译： 分布式心脏起搏系统包括适于放置在心房心肌中的第一超微型集成心脏起搏器和适于放置在心室心肌中的第二超微型集成心脏起搏器。
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5.发明授权System for automatically minimizing cardiac oxygen consumption and cardiac disease treating system using the same 有权用于自动最小化心脏氧消耗的系统和使用其的心脏疾病治疗系统公开(公告)号：US08340749B2
公开(公告)日：2012-12-25
申请号：US12279753
申请日：2007-02-16
IPC分类号： A61B5/04
CPC分类号： A61B5/0215 , A61B5/029 , A61B5/4866 , A61N1/36557
摘要： A cardiac disease treating system has an input part for inputting a patient's indexes of kinetics of blood circulation including at least heart rate, a cardiac oxygen consumption calculation monitor unit for calculating the estimated value of said patient's amount of cardiac oxygen consumption based on the indexes of kinetics of blood circulation input from the input part, and a cardiac oxygen consumption curtailment unit for comparing the heart rate input from the input part and the critical heart rate minimizing the estimated value of amount of cardiac oxygen consumption calculated by the cardiac oxygen consumption monitor unit and controlling the patient's heart rate in conformity with the results of this comparison.
摘要翻译： 心脏疾病治疗系统具有输入部，用于输入至少包括心率的患者的血液循环动力学指标，心脏耗氧量计算监测单元，用于根据患者的心脏氧消耗量的指标计算所述患者心脏耗氧量的估计值 从输入部输入的血液循环的动力学，以及用于比较从输入部输入的心率和临床心率的心脏氧消耗量缩小单元，其将由心脏氧消耗监测单元计算出的心脏氧消耗量的估计值减至最小 并根据该比较的结果控制患者的心率。
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公开(公告)号：US08282563B2
公开(公告)日：2012-10-09
申请号：US11719400
申请日：2004-11-18
IPC分类号： A61B5/02
CPC分类号： A61M5/1723 , A61B5/02028 , A61B5/02158 , A61B5/029 , A61M5/14244 , A61M2230/30
摘要： ProblemsTo provide a cardiac disease treatment system for accurately diagnosing the functional cause of an abnormality of a cardiac disease by analyzing the hemodynamic state of a patient, automatically performing medication in accordance with the diagnosis result, and treating the cardiac disease.Means for solving problemsThe cardiac disease treatment system is characterized by comprising input means (2) for inputting the cardiac output value of the patient, the left atrial pressure value and/or the right atrial pressure value, first calculating means (31) for calculating the pumping ability value of the left heart or the right heart from the inputted cardiac output and the left or right atrial pressure value, first comparing means (41) for comparing the pumping ability value of the left heart or the right heart with a target pumping ability value, and first medicating means (51) for medicating the patient in accordance with the result of the comparison by the first comparing means (41).
摘要翻译： 问题提供一种心脏疾病治疗系统，用于通过分析患者的血液动力学状态，根据诊断结果自动进行药物，以及治疗心脏病，来准确诊断心脏病异常的功能原因。 解决问题的手段心脏疾病治疗系统的特征在于包括用于输入患者的心输出量的输入装置（2），左心房压力值和/或右心房压力值，第一计算装置（31），用于计算 来自输入的心输出量的左心脏或右心脏的泵送能力值和左心房或右心房压力值，用于将左心脏或右心脏的抽吸能力值与目标泵送的第一比较装置（41） 能力值，以及用于根据第一比较装置（41）的比较结果对患者进行治疗的第一药剂装置（51）。
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7.发明授权公开(公告)号：US08027729B2
公开(公告)日：2011-09-27
申请号：US10523538
申请日：2003-08-04
IPC分类号： A61N1/375
CPC分类号： A61N1/37288 , A61N1/368 , A61N1/37205 , A61N1/3756 , A61N1/3785 , H01M8/16 , Y02E60/527
摘要： A micro integrated cardiac pacemaker includes a control unit for outputting a control signal according to cardiograph information, heart stimulating means for stimulating heart tissue in response to the control signal, cardiograph information extracting means for extracting cardiograph information and outputting it to the control unit, and a power supply unit for supplying drive power. The power supply unit is a biological fuel cell that takes out electrons by oxidation of a biological fuel. The biological fuel cell includes an anode and a cathode. An oxidase of a biological fuel and a mediator are immobilized on the cathode. Blood and/or body fluid are used as an electrolytic solution, and a biological fuel and oxygen in the blood and/or the fluid are used. The biological fuel cell is attached to the end of a catheter and implanted into the heart, and the catheter is withdrawn, without incising the breast.
摘要翻译： 微型集成心脏起搏器包括：用于根据心电图信息输出控制信号的控制单元，响应于控制信号刺激心脏组织的心脏刺激装置;心电图仪信息提取装置，用于提取心电图信息并将其输出到控制单元;以及 用于提供驱动电力的电源单元。 电源单元是通过生物燃料的氧化而取出电子的生物燃料电池。 生物燃料电池包括阳极和阴极。 将生物燃料和介体的氧化酶固定在阴极上。 使用血液和/或体液作为电解液，并且使用血液和/或流体中的生物燃料和氧气。 生物燃料电池连接到导管的末端并植入心脏，导管被取出，而不会切开乳房。
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8.发明申请公开(公告)号：US20050288718A1
公开(公告)日：2005-12-29
申请号：US10523539
申请日：2002-08-05
申请人： Kenji Sunagawa , Masaru Sugimachi , Takayuki Sato
发明人： Kenji Sunagawa , Masaru Sugimachi , Takayuki Sato
CPC分类号： A61N1/36114 , A61N1/365 , A61N1/36514
摘要： A medical treating system based on biological activities characterized by biological activity sensing means for sensing biological activity information produced by biological activities and outputting a biological activity signal, calculating means for receiving, analyzing, and processing the biological activity signals from the biological activity sensing means, calculating an organism stimulation signal, and outputting the organism stimulation signal, and organism stimulating means for receiving the organism stimulation signal calculated by the calculating means and stimulating an organism according to the organism stimulation signal. A cardiac pacing system based on the treating system, a blood pressure regulating system, and a cardiac disease treating system are also disclosed.
摘要翻译： 一种基于生物活性的医疗处理系统，其特征在于用于感测由生物活性产生的生物活性信息并输出生物活性信号的生物活性检测装置，用于接收，分析和处理来自生物活性检测装置的生物活性信号的计算装置， 计算生物体刺激信号，并输出生物体刺激信号，以及生物体刺激装置，用于接收由计算装置计算的生物体刺激信号，并根据生物体刺激信号刺激生物体。 还公开了一种基于治疗系统，血压调节系统和心脏疾病治疗系统的心脏起搏系统。
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9.发明申请APPARATUS FOR BODY SURFACE STIMULATION TREATMENT, PROGRAM FOR BODY SURFACE STIMULATION TREATMENT, AND COMPUTER-READABLE RECORDING MEDIUM HAVING RECORDED THE SAME 审中-公开用于身体表面刺激治疗的装置，身体表面刺激治疗程序和具有记录的计算机可读记录介质公开(公告)号：US20110034782A1
公开(公告)日：2011-02-10
申请号：US12095629
申请日：2006-11-29
CPC分类号： A61H39/04 , A61B5/021 , A61B5/024 , A61B5/026 , A61B5/0402 , A61B5/4854 , A61F2007/0296 , A61H2201/5058 , A61N1/322 , A61N1/36014
摘要： [Problems] To provide an apparatus for a body surface stimulation treatment capable of overcoming the uncertainty in the existing body surface stimulation therapy and exhibiting stable therapeutic effects.[Means for Solving Problems] An apparatus for a body surface stimulation treatment (10) which comprises a body surface stimulation unit (16) whereby the body surface of a patient is physically or chemically stimulated, a vital reaction quantitative evaluation unit (12) whereby the vital reaction of the patient is quantitatively evaluated, and a body surface stimulation regulation unit (14) whereby the stimulation properties imparted to the body surface tissues of the patient by the body surface stimulation unit (16) are regulated depending on the vital data obtained by the vital reaction quantitative evaluation unit (12).
摘要翻译： [问题]提供一种能够克服现有体表刺激疗法的不确定性并表现出稳定的治疗效果的体表刺激治疗装置。 解决问题的手段一种身体表面刺激治疗装置（10），其特征在于，包括身体表面刺激部（16），由此身体或化学刺激患者的身体表面，生物反应定量评价部（12） 对患者的重要反应进行定量评价，并且根据获得的生命数据来调节身体表面刺激调节单元（14），由身体表面刺激单元（16）赋予患者体表组织的刺激特性 由生命反应定量评价单位（12）。
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10.发明授权公开(公告)号：US07835791B2
公开(公告)日：2010-11-16
申请号：US10523539
申请日：2002-08-05
申请人： Kenji Sunagawa , Masaru Sugimachi , Takayuki Sato
发明人： Kenji Sunagawa , Masaru Sugimachi , Takayuki Sato
IPC分类号： A61N1/365
CPC分类号： A61N1/36114 , A61N1/365 , A61N1/36514
摘要： A medical treating system based on biological activities characterized by biological activity sensing means for sensing biological activity information produced by biological activities and outputting a biological activity signal, calculating means for receiving, analyzing, and processing the biological activity signals from the biological activity sensing means, calculating an organism stimulation signal, and outputting the organism stimulation signal, and organism stimulating means for receiving the organism stimulation signal calculated by the calculating means and stimulating an organism according to the organism stimulation signal. A cardiac pacing system based on the treating system, a blood pressure regulating system, and a cardiac disease treating system are also disclosed.
摘要翻译： 一种基于生物活性的医疗处理系统，其特征在于用于感测由生物活性产生的生物活性信息并输出生物活性信号的生物活性检测装置，用于接收，分析和处理来自生物活性检测装置的生物活性信号的计算装置， 计算生物体刺激信号，并输出生物体刺激信号，以及生物体刺激装置，用于接收由计算装置计算的生物体刺激信号，并根据生物体刺激信号刺激生物体。 还公开了一种基于治疗系统，血压调节系统和心脏疾病治疗系统的心脏起搏系统。
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