摘要:
This invention provides a nucleic acid sequence encoding a trypsin-like enzyme which can be present at the trachea of human lungs, and can selectively digest a synthetic substrate for trypsin and a synthetic substrate for thrombin, and fibrinogen; and a process for producing the trypsin-like enzyme by genetic engineering utilizing the nucleic acid sequence.
摘要:
A recording liquid comprises a liquid composition containing water-soluble dyes as coloring component, characterized in that C.I. Food Black 2 and one or more dyes in different color or colors are used in combination as said coloring component.
摘要:
A compound having GSK-3 inhibiting function. A1 and A3 are a single bond, an aliphatic hydrocarbon group; A2 and A4 are a single bond, CO, COO, CONR, O, OCO, NR, NRCO, NRCOO, etc.; G1 is a single bond, an aliphatic hydrocarbon, aromatic hydrocarbon, heterocyclic; G2 is a hydrogen atom, an aliphatic hydrocarbon, an alicyclic hydrocarbon, an aromatic hydrocarbon, heterocyclic; A5 is a single bond, NR; R2 is H, halogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; A6 is a single bond, NR, CO, NRCO, NRCONR, CONR, COO, O, etc.; R3 is H, halogen, nitro, saturated aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; and when A6 is CR═CR or C≡C; R3 may be a trimethylsilyl, formyl, acyl, carboxyl, alkoxylcarbonyl, carbamoyl, alkylcarbamoyl or cyano group; and R is H or an aliphatic hydrocarbon group.
摘要翻译:具有GSK-3抑制功能的化合物。 A 1和A 3是单键,脂族烃基; A <2>和A 4是单键,CO,COO,CONR,O,OCO,NR,NRCO,NRCOO等; G 1是单键,脂族烃,芳族烃,杂环基; G 2是氢原子,脂族烃,脂环烃,芳族烃,杂环基; A <5>是单键NR; R 2是H,卤素,脂族烃,脂环烃,芳烃,杂环; NR 6 CO 2,NRCO,NRCONR,CONR,COO,O等单键。 R 3是H,卤素,硝基,饱和脂族烃,脂环烃,芳族烃,杂环; 当A <6> CR-CR或C≡C时; R 3可以是三甲基甲硅烷基,甲酰基,酰基,羧基,烷氧基羰基,氨基甲酰基,烷基氨基甲酰基或氰基; R为H或脂族烃基。
摘要:
Block copolymers of a vinyl-substituted aromatic hydrocarbon and a conjugated diene, having alkali metal atoms linked to at least one terminal of the polymer chain are obtained by polymerizing vinyl-substituted aromatic hydrocarbon and conjugated diene monomers with use of an alkali metal or organo alkali metal initiator. The block copolymer thus obtained is treated with a polar reactant to introduce polar groups into the polymer chain terminal.Compositions for paints and printing inks are prepared by incorporating inorganic pigments into the block copolymer having the terminal polar group.
摘要:
A compound having GSK-3 inhibitory activity. A1 and A3 are a single bond, an aliphatic hydrocarbon group; A2 and A4 are a single bond, CO, COO, CONR, O, OCO, NR, NRCO, NRCOO, etc.; G1 is a single bond, an aliphatic hydrocarbon, aromatic hydrocarbon, heterocyclic; G2 is H, an aliphatic hydrocarbon, an alicyclic hydrocarbon, an aromatic hydrocarbon, heterocyclic; A5 is a single bond, NR; R2 is H, halogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; A6 is a single bond, NR, CO, NRCO, NRCONR, CONR, COO, O, etc.; R3 is H, halogen, nitro, saturated aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; and R3 may be a trimethylsilyl, formyl, acyl, carboxyl, alkoxylcarbonyl, carbamoyl, alkylcarbamoyl, or cyano group when A6 is CR═CR or C≡C, wherein R is H or an lower aliphatic hydrocarbon group.
摘要:
A compound having GSK-3 inhibitory activity. A1 and A3 are a single bond, an aliphatic hydrocarbon group; A2 and A4 are a single bond, CO, COO, CONR, O, OCO, NR, NRCO, NRCOO, etc.; G1 is a single bond, an aliphatic hydrocarbon, aromatic hydrocarbon, heterocyclic; G2 is H, an aliphatic hydrocarbon, an alicyclic hydrocarbon, an aromatic hydrocarbon, heterocyclic; A5 is a single bond, NR; R2 is H, halogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; A6 is a single bond, NR, CO, NRCO, NRCONR, CONR, COO, O, etc.; R3 is H, halogen, nitro, saturated aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; and R3 may be a trimethylsilyl, formyl, acyl, carboxyl, alkoxylcarbonyl, carbamoyl, alkylcarbamoyl, or cyano group when A6 is CR═CR or C≡C, wherein R is H or an lower aliphatic hydrocarbon group.
摘要翻译:具有GSK-3抑制活性的化合物。 A 1和A 3是单键,脂族烃基; A <2>和A 4是单键,CO,COO,CONR,O,OCO,NR,NRCO,NRCOO等; G 1是单键,脂族烃,芳族烃,杂环基; G 2是H,脂族烃,脂环烃,芳族烃,杂环基; A <5>是单键NR; R 2是H,卤素,脂族烃,脂环烃,芳烃,杂环; NR 6 CO 2,NRCO,NRCONR,CONR,COO,O等单键。 R 3是H,卤素,硝基,饱和脂族烃,脂环烃,芳族烃,杂环; 当A 6是CR-CR或C≡C时,R 3可以是三甲基甲硅烷基,甲酰基,酰基,羧基,烷氧基羰基,氨基甲酰基,烷基氨基甲酰基或氰基,其中 R是H或低级脂族烃基。