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1.发明授权
公开(公告)号：US4933323A
公开(公告)日：1990-06-12
申请号：US315285
申请日：1989-02-24
CPC分类号： C07K16/065 , A61K38/00 , Y02P20/55
摘要： Novel peptide having the primary structure Asp-Ser-Asp-Gly-Lys or pharmaceutically acceptable salts thereof.The present peptide possesses activity of inhibiting histamine release and IgE antibody production in the onset of type I-allergy and is effective in the prevention or therapy of type I-allergias such as bronchial asthma, urticaria and allergic rhinitis.
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公开(公告)号：US5223487A
公开(公告)日：1993-06-29
申请号：US824589
申请日：1992-01-23
申请人： Keiichi Noguchi , Noriya Ohta , Daisuke Irie , Katsurou Matsuo , Kouhei Hirano , Asako Tokunaga , Fumio Ishikawa
发明人： Keiichi Noguchi , Noriya Ohta , Daisuke Irie , Katsurou Matsuo , Kouhei Hirano , Asako Tokunaga , Fumio Ishikawa
CPC分类号： C07K7/06 , C07K16/065 , C07K5/0819 , C07K5/1013 , A61K38/00
摘要： The following oligopeptides containing -Asp-Gly- or -Asp-Ser- are synthesized:H-Asp-Gly-Lys-OHH-Ser-Asp-Gly-Lys-OHH-Asp-Ser-Asp-Gly-Lys-OHH-Ala-Asp-Ser-Asp-Gly-Lys-OHThe oligopeptides have antiallergic, vasodilating and immunoregulating activities and are very useful for treating allergic symptoms.
摘要翻译： 合成以下含有-Asp-Gly-或-Asp-Ser-的寡肽：H-Asp-Gly-Lys-OH H-Ser-Asp-Gly-Lys-OH H-Asp-Ser-Asp-Gly-Lys- OH H-Ala-Asp-Ser-Asp-Gly-Lys-OH寡肽具有抗过敏，血管扩张和免疫调节活性，对治疗过敏性症状非常有用。
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3.发明授权Peptides and intermediates therefor useful as antiallergic agents, vasodilators and immunoregulators 失效其作为抗菌剂，血管扩张剂和免疫球蛋白的有用的中间体
公开(公告)号：US5118669A
公开(公告)日：1992-06-02
申请号：US587967
申请日：1990-09-25
申请人： Keiichi Noguchi , Noriya Ohta , Daisuke Irie , Katsurou Matsuo , Kouhei Hirano , Asako Tokunaga , Fumio Ishikawa
发明人： Keiichi Noguchi , Noriya Ohta , Daisuke Irie , Katsurou Matsuo , Kouhei Hirano , Asako Tokunaga , Fumio Ishikawa
CPC分类号： C07K7/06 , C07K16/065 , C07K5/0819 , C07K5/1013 , A61K38/00
摘要： The following oligopeptides containing -Asp-Gly- or -Asp-Ser- are synthesized:H-Asp-Gly-Lys-OHH-Ser-Asp-Gly-Lys-OHH-Asp-Ser-Asp-Gly-Lys-OHH-Ala-Asp-Ser-Asp-Gly-Lys-OHThe oligopeptides have antiallergic, vasodilating and immunoregulating activities and are very useful for treating allergic symptons.
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公开(公告)号：US4923115A
公开(公告)日：1990-05-08
申请号：US188794
申请日：1988-03-17
CPC分类号： G05D23/136 , Y10T137/2499
摘要： A mixing valve apparatus is disclosed, for producing a mixed fluid of a desired temperature obtained by mixing high temperature fluid and low temperature fluid with each other. The apparatus includes a pressure-sensitive control unit (6) which operates in response to the differential pressure (.DELTA.P) between the inlet pressure of the low temperature fluid and the pressure of the mixed fluid, and which unit controls the opening degree of an inlet valve (V.sub.1) for the high temperature fluid. Pilot passage (R.sub.0 .about.R.sub.3) for communicating the inlet pressure of the low temperature fluid to said unit is provided with a throttle (L, L.sub.1) whose effective surface area varies in response to the temperature of the mixed fluid, to compensate the opening degree of the inlet valve (V.sub.1) for the high temperature fluid upon variation of the temperature of the mixed fluid.
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公开(公告)号：US4471906A
公开(公告)日：1984-09-18
申请号：US184327
申请日：1980-09-05
摘要： A thermostatically controlled trap provided that one end of a valve pushrod comes in direct contact with a ball valve when the valve pushrod is subjected to axial motion by the expansion of a thermosensitive member caused by a change in the temperature of a fluid flowing through the trap.
摘要翻译： 恒温控制的捕集器，当阀推杆的一端与球阀直接接触时，阀推动器通过由流过捕集器的流体的温度变化引起的热敏元件的膨胀而受到轴向运动 。
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