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1.发明申请公开(公告)号：US20110077707A1
公开(公告)日：2011-03-31
申请号：US12955065
申请日：2010-11-29
IPC分类号： A61N1/365
CPC分类号： A61N1/36542 , A61N1/36585
摘要： An implantable medical device includes a dual-use sensor such as a single accelerometer that senses an acceleration signal. A sensor processing circuit processes the acceleration signal to produce an activity level signal and a heart sound signal. The implantable medical device provides for rate responsive pacing in which at least one pacing parameter, such as the pacing interval, is dynamically adjusted based on the physical activity level. The implantable medical device also uses the heart sounds for pacing control purposes or transmits a heart sound signal to an external system for pacing control and/or diagnostic purposes.
摘要翻译： 可植入医疗装置包括感测加速度信号的诸如单个加速度计的双重用途传感器。 传感器处理电路处理加速度信号以产生活动度信号和心音信号。 可植入医疗装置提供速率响应起搏，其中基于身体活动水平动态地调整至少一个起搏参数，例如起搏间隔。 可植入医疗装置还使用心脏声音用于起搏控制目的，或者将心音信号发送到外部系统用于起搏控制和/或诊断目的。
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2.发明授权公开(公告)号：US07844334B2
公开(公告)日：2010-11-30
申请号：US11778527
申请日：2007-07-16
IPC分类号： A61N1/00
CPC分类号： A61N1/36542 , A61N1/36585
摘要： An implantable medical device includes a dual-use sensor such as a single accelerometer that senses an acceleration signal. A sensor processing circuit processes the acceleration signal to produce an activity level signal and a heart sound signal. The implantable medical device provides for rate responsive pacing in which at least one pacing parameter, such as the pacing interval, is dynamically adjusted based on the physical activity level. The implantable medical device also uses the heart sounds for pacing control purposes or transmits a heart sound signal to an external system for pacing control and/or diagnostic purposes.
摘要翻译： 可植入医疗装置包括感测加速度信号的诸如单个加速度计的双重用途传感器。 传感器处理电路处理加速度信号以产生活动度信号和心音信号。 可植入医疗装置提供速率响应起搏，其中基于身体活动水平动态地调整至少一个起搏参数，例如起搏间隔。 可植入医疗装置还使用心脏声音用于起搏控制目的，或者将心音信号发送到外部系统用于起搏控制和/或诊断目的。
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公开(公告)号：US20090247889A1
公开(公告)日：2009-10-01
申请号：US12484108
申请日：2009-06-12
IPC分类号： A61B5/02
CPC分类号： A61N1/36542 , A61B7/00 , A61N1/36535 , A61N1/36578
摘要： A system for determining a patient's posture by monitoring heart sounds. The system comprises an implantable medical device that includes a sensor operable to produce an electrical signal representative of heart sounds, a sensor interface circuit coupled to the sensor to produce a heart sound signal, and a controller circuit coupled to the sensor interface circuit. The heart sounds are associated with mechanical activity of a patient's heart and the controller circuit is operable to detect a posture of the patient from a heart sound signal.
摘要翻译： 通过监测心脏声音来确定患者姿势的系统。 该系统包括可植入医疗装置，其包括可操作以产生表示心脏声音的电信号的传感器，耦合到传感器以产生心音信号的传感器接口电路，以及耦合到传感器接口电路的控制器电路。 心脏声音与患者心脏的机械活动相关联，并且控制器电路可操作以从心脏声音信号检测患者的姿势。
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公开(公告)号：US08012098B2
公开(公告)日：2011-09-06
申请号：US12484108
申请日：2009-06-12
IPC分类号： A61B5/02
CPC分类号： A61N1/36542 , A61B7/00 , A61N1/36535 , A61N1/36578
摘要： A system for determining a patient's posture by monitoring heart sounds. The system comprises an implantable medical device that includes a sensor operable to produce an electrical signal representative of heart sounds, a sensor interface circuit coupled to the sensor to produce a heart sound signal, and a controller circuit coupled to the sensor interface circuit. The heart sounds are associated with mechanical activity of a patient's heart and the controller circuit is operable to detect a posture of the patient from a heart sound signal.
摘要翻译： 通过监测心脏声音来确定患者姿势的系统。 该系统包括可植入医疗装置，其包括可操作以产生表示心脏声音的电信号的传感器，耦合到传感器以产生心音信号的传感器接口电路，以及耦合到传感器接口电路的控制器电路。 心脏声音与患者心脏的机械活动相关联，并且控制器电路可操作以从心脏声音信号检测患者的姿势。
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公开(公告)号：US07951087B2
公开(公告)日：2011-05-31
申请号：US12645906
申请日：2009-12-23
IPC分类号： A61B5/02
CPC分类号： A61B7/04 , A61B5/1116 , A61B8/0883 , A61N1/3627 , A61N1/36535 , A61N1/36578 , A61N1/36585
摘要： A system to monitor heart sounds. The system comprises an implantable heart sound sensor configured to produce an electrical signal representative of at least one heart sound, an implantable posture sensor operable to produce an electrical signal representative of a patient's posture, and a controller circuit. The controller circuit is configured to determine a patient posture, measure at least one heart sound in correspondence with at least one corresponding patient posture, adjust the heart sound measurement by using the corresponding determined patient posture to reduce or remove variation in the heart sound measurement due to patient posture, detect a change in the adjusted heart sound measurement, and provide an indication of congestive heart failure to a user or an automated process in response to the detected change.
摘要翻译： 监听心音的系统 该系统包括被配置为产生表示至少一个心音的电信号的可植入心音传感器，可操作以产生表示患者姿势的电信号的可植入姿态传感器和控制器电路。 控制器电路被配置为确定患者姿势，测量与至少一个对应的患者姿势相对应的至少一个心音，通过使用相应的确定的患者姿势来调整心脏声音测量，以减少或消除心音测量中的变化 到患者姿势，检测调整后的心音测量的变化，并响应于检测到的变化向用户或自动化过程提供充血性心力衰竭的指示。
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公开(公告)号：US07662104B2
公开(公告)日：2010-02-16
申请号：US11037275
申请日：2005-01-18
IPC分类号： A61B5/02
CPC分类号： A61B7/04 , A61B5/1116 , A61B8/0883 , A61N1/3627 , A61N1/36535 , A61N1/36578 , A61N1/36585
摘要： A system to monitor heart sounds. The system comprises an implantable heart sound sensor operable to produce an electrical signal representative of at least one heart sound, a heart sound sensor interface circuit coupled to the heart sound sensor to produce a heart sound signal, an implantable posture sensor operable to produce an electrical signal representative of a patient's posture, and a controller circuit, coupled to the heart sound sensor interface circuit and the posture circuit. The controller circuit is operable to measure at least one heart sound in correspondence with at least one sensed patient posture.
摘要翻译： 监听心音的系统 该系统包括可植入的心音传感器，其可操作以产生表示至少一个心音的电信号，耦合到心音传感器以产生心音信号的心音传感器接口电路，可操作以产生电声 代表患者姿势的信号，以及耦合到心脏声音传感器接口电路和姿势电路的控制器电路。 控制器电路可操作以对应于至少一个感测到的患者姿势来测量至少一个心音。
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公开(公告)号：US07559901B2
公开(公告)日：2009-07-14
申请号：US10900570
申请日：2004-07-28
IPC分类号： A61B5/02
CPC分类号： A61N1/36542 , A61B7/00 , A61N1/36535 , A61N1/36578
摘要： A system for determining a patient's posture by monitoring heart sounds. The system comprises an implantable medical device that includes a sensor operable to produce an electrical signal representative of heart sounds, a sensor interface circuit coupled to the sensor to produce a heart sound signal, and a controller circuit coupled to the sensor interface circuit. The heart sounds are associated with mechanical activity of a patient's heart and the controller circuit is operable to detect a posture of the patient from a heart sound signal.
摘要翻译： 通过监测心脏声音来确定患者姿势的系统。 该系统包括可植入医疗装置，其包括可操作以产生表示心脏声音的电信号的传感器，耦合到传感器以产生心音信号的传感器接口电路，以及耦合到传感器接口电路的控制器电路。 心脏声音与患者心脏的机械活动相关联，并且控制器电路可操作以从心脏声音信号检测患者的姿势。
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公开(公告)号：US20100099997A1
公开(公告)日：2010-04-22
申请号：US12645906
申请日：2009-12-23
IPC分类号： A61B5/02
CPC分类号： A61B7/04 , A61B5/1116 , A61B8/0883 , A61N1/3627 , A61N1/36535 , A61N1/36578 , A61N1/36585
摘要： A system to monitor heart sounds. The system comprises an implantable heart sound sensor configured to produce an electrical signal representative of at least one heart sound, an implantable posture sensor operable to produce an electrical signal representative of a patient's posture, and a controller circuit. The controller circuit is configured to determine a patient posture, measure at least one heart sound in correspondence with at least one corresponding patient posture, adjust the heart sound measurement by using the corresponding determined patient posture to reduce or remove variation in the heart sound measurement due to patient posture, detect a change in the adjusted heart sound measurement, and provide an indication of congestive heart failure to a user or an automated process in response to the detected change.
摘要翻译： 监听心音的系统 该系统包括被配置为产生表示至少一个心音的电信号的可植入心音传感器，可操作以产生表示患者姿势的电信号的可植入姿态传感器和控制器电路。 控制器电路被配置为确定患者姿势，测量与至少一个对应的患者姿势相对应的至少一个心音，通过使用相应的确定的患者姿势来调整心脏声音测量，以减少或消除心音测量中的变化 到患者姿势，检测调整后的心音测量的变化，并响应于检测到的变化向用户或自动化过程提供充血性心力衰竭的指示。
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9.发明授权公开(公告)号：US07248923B2
公开(公告)日：2007-07-24
申请号：US10703175
申请日：2003-11-06
IPC分类号： A61N1/365
CPC分类号： A61N1/36542 , A61N1/36585
摘要： An implantable medical device includes a dual-use sensor such as a single accelerometer that senses an acceleration signal. A sensor processing circuit processes the acceleration signal to produce an activity level signal and a heart sound signal. The implantable medical device provides for rate responsive pacing in which at least one pacing parameter, such as the pacing interval, is dynamically adjusted based on the physical activity level. The implantable medical device also uses the heart sounds for pacing control purposes or transmits a heart sound signal to an external system for pacing control and/or diagnostic purposes.
摘要翻译： 可植入医疗装置包括感测加速度信号的诸如单个加速度计的双重用途传感器。 传感器处理电路处理加速度信号以产生活动度信号和心音信号。 可植入医疗装置提供速率响应起搏，其中基于身体活动水平动态地调整至少一个起搏参数，例如起搏间隔。 可植入医疗装置还使用心脏声音用于起搏控制目的，或者将心音信号发送到外部系统用于起搏控制和/或诊断目的。
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公开(公告)号：US08700149B2
公开(公告)日：2014-04-15
申请号：US13479979
申请日：2012-05-24
IPC分类号： A61N1/365
CPC分类号： A61N1/3627 , A61B5/0031 , A61B5/02028 , A61B5/0215 , A61B5/029 , A61B5/0422 , A61B5/0535 , A61B5/0538 , A61B5/1102 , A61B5/7267 , A61B7/00 , A61N1/3684 , A61N1/3704
摘要： Systolic timing intervals are measured in response to delivering pacing energy to a pacing site of a patient's heart. An estimate of a patient's acute response to cardiac resynchronization therapy (CRT) for the pacing site is determined using the measured systolic timing intervals. The estimate is compared to a threshold. The threshold preferably distinguishes between acute responsiveness and non-responsiveness to CRT for a patient population. An indication of acute responsiveness to CRT for the pacing site may be produced in response to the comparison.
摘要翻译： 响应于将起搏能量递送到患者心脏的起搏部位来测量收缩时间间隔。 使用测量的收缩时间间隔来确定对于起搏部位的患者对心脏再同步治疗（CRT）的急性反应的估计。 将估计值与阈值进行比较。 该阈值优选地区分对于患者群体的急性反应性和对CRT的无反应性。 响应于比较可以产生针对起搏部位对CRT的急性反应性的指示。
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