公开(公告)号：US20050245459A1

公开(公告)日：2005-11-03

申请号：US10515018

申请日：2003-05-22

申请人： Ken Izumori ,  Masaaki Tokuda ,  Toshifumi Itano ,  Osamu Miyamoto ,  Toshihiko Ishida ,  Koji Murao ,  Taizo Tasaka ,  Gan Muneuchi ,  Fuminori Yamaguchi ,  Terukazu Tanaka ,  Masaaki Ueki ,  Kazuyuki Hirooka ,  Tomohiko Taminato ,  Mohammad Hossain ,  Keiji Tsusaki ,  Takeo Takahashi ,  Mitsuhiro Nagata ,  Yutaka Ishida

发明人： Ken Izumori ,  Masaaki Tokuda ,  Toshifumi Itano ,  Osamu Miyamoto ,  Toshihiko Ishida ,  Koji Murao ,  Taizo Tasaka ,  Gan Muneuchi ,  Fuminori Yamaguchi ,  Terukazu Tanaka ,  Masaaki Ueki ,  Kazuyuki Hirooka ,  Tomohiko Taminato ,  Mohammad Hossain ,  Keiji Tsusaki ,  Takeo Takahashi ,  Mitsuhiro Nagata ,  Yutaka Ishida

IPC分类号： A23L1/09 ,  A23L1/30 ,  A61K8/60 ,  A61K31/7004 ,  A61Q19/00 ,  C12N5/08 ,  A61K31/70 ,  A61K31/715

CPC分类号： A61Q19/00 ,  A23L5/00 ,  A23L29/30 ,  A23L33/10 ,  A23L33/125 ,  A61K8/60 ,  A61K31/7004

摘要： A method of utilizing the physiological activity of a rare saccharide, wherein physiological-activity sensitive cells are treated with the rare saccharide to modify the function of the cells. A composition containing, as an active ingredient, a rare saccharide which is introduced into physiological-activity sensitive cells and has an effect of modifying the function of the cells. The cells are human cells. The composition is a functional food, a drug, or a cosmetic. The rare saccharide is a rare saccharide belonging to aldose and/or ketose. The aldose is D-allose, and the cells are selected from the group consisting of cancer-cell proliferation inhibitory activity sensitive cells and active-oxygen production inhibitory activity sensitive cells. The ketose is D-psicose, and the cells are selected from the group consisting of chemokine secretion inhibitory activity sensitive cells, microglia migration inhibitory activity sensitive cells, and hypoglycemic activity sensitive cells.

摘要翻译： 利用稀有糖类的生理活性的方法，其中用稀有糖类处理生理活性敏感性细胞以改变细胞的功能。 作为活性成分含有引入生理活性敏感性细胞的稀有糖类并具有改变细胞功能的作用的组合物。 细胞是人细胞。 组合物是功能性食品，药物或化妆品。 罕见的糖是属于醛糖和/或酮糖的稀有糖。 醛糖是D-丙氨酸，细胞选自癌细胞增殖抑制活性敏感细胞和活性氧生成抑制活性敏感细胞。 酮糖是D-psicose，细胞选自趋化因子分泌抑制活性敏感细胞，小胶质细胞迁移抑制活性敏感细胞和低血糖活性敏感细胞。

公开(公告)号：US08420606B2

公开(公告)日：2013-04-16

申请号：US13007058

申请日：2011-01-14

申请人： Ken Izumori ,  Masaaki Tokuda ,  Toshifumi Itano ,  Osamu Miyamoto ,  Toshihiko Ishida ,  Koji Murao ,  Taizo Tasaka ,  Gan Muneuchi ,  Fuminori Yamaguchi ,  Terukazu Tanaka ,  Masaaki Ueki ,  Kazuyuki Hirooka ,  Tomohiko Taminato ,  Mohammad A. Hossain ,  Keiji Tsusaki ,  Takeo Takahashi ,  Mitsuhiro Nagata ,  Yutaka Ishida

发明人： Ken Izumori ,  Masaaki Tokuda ,  Toshifumi Itano ,  Osamu Miyamoto ,  Toshihiko Ishida ,  Koji Murao ,  Taizo Tasaka ,  Gan Muneuchi ,  Fuminori Yamaguchi ,  Terukazu Tanaka ,  Masaaki Ueki ,  Kazuyuki Hirooka ,  Tomohiko Taminato ,  Mohammad A. Hossain ,  Keiji Tsusaki ,  Takeo Takahashi ,  Mitsuhiro Nagata ,  Yutaka Ishida

IPC分类号： A61K31/7004 ,  A61K31/70

CPC分类号： A61Q19/00 ,  A23L5/00 ,  A23L29/30 ,  A23L33/10 ,  A23L33/125 ,  A61K8/60 ,  A61K31/7004

摘要： A method of utilizing the physiological activity of a rare saccharide, wherein physiological-activity sensitive cells are treated with the rare saccharide to modify the function of the cells. A composition containing, as an active ingredient, a rare saccharide which is introduced into physiological-activity sensitive cells and has an effect of modifying the function of the cells. The cells are human cells. The composition is a functional food, a drug, or a cosmetic. The rare saccharide is a rare saccharide belonging to aldose and/or ketose. The aldose is D-allose, and the cells are selected from the group consisting of cancer-cell proliferation inhibitory activity sensitive cells and active-oxygen production inhibitory activity sensitive cells. The ketose is D-psicose, and the cells are selected from the group consisting of chemokine secretion inhibitory activity sensitive cells, microglia migration inhibitory activity sensitive cells, and hypoglycemic activity sensitive cells.

摘要翻译： 利用稀有糖类的生理活性的方法，其中用稀有糖类处理生理活性敏感性细胞以改变细胞的功能。 作为活性成分含有引入生理活性敏感性细胞的稀有糖类并具有改变细胞功能的作用的组合物。 细胞是人细胞。 组合物是功能性食品，药物或化妆品。 罕见的糖是属于醛糖和/或酮糖的稀有糖。 醛糖是D-丙氨酸，细胞选自癌细胞增殖抑制活性敏感细胞和活性氧生成抑制活性敏感细胞。 酮糖是D-psicose，细胞选自趋化因子分泌抑制活性敏感细胞，小胶质细胞迁移抑制活性敏感细胞和低血糖活性敏感细胞。

公开(公告)号：US20110112043A1

公开(公告)日：2011-05-12

申请号：US13007058

申请日：2011-01-14

申请人： Ken Izumori ,  Masaaki Tokuda ,  Toshifumi Itano ,  Osamu Miyamoto ,  Toshihiko Ishida ,  Koji Murao ,  Taizo Tasaka ,  Gan Muneuchi ,  Fuminori Yamaguchi ,  Terukazu Tanaka ,  Masaaki Ueki ,  Kazuyuki Hirooka ,  Tomohiko Taminato ,  Mohammad Akram Hossain ,  Keiji Tsusaki ,  Takeo Takahashi ,  Mitsuhiro Nagata ,  Yutaka Ishida

发明人： Ken Izumori ,  Masaaki Tokuda ,  Toshifumi Itano ,  Osamu Miyamoto ,  Toshihiko Ishida ,  Koji Murao ,  Taizo Tasaka ,  Gan Muneuchi ,  Fuminori Yamaguchi ,  Terukazu Tanaka ,  Masaaki Ueki ,  Kazuyuki Hirooka ,  Tomohiko Taminato ,  Mohammad Akram Hossain ,  Keiji Tsusaki ,  Takeo Takahashi ,  Mitsuhiro Nagata ,  Yutaka Ishida

IPC分类号： A61K31/7004 ,  A61P35/04 ,  A61P25/00

CPC分类号： A61Q19/00 ,  A23L5/00 ,  A23L29/30 ,  A23L33/10 ,  A23L33/125 ,  A61K8/60 ,  A61K31/7004

摘要： A method of utilizing the physiological activity of a rare saccharide, wherein physiological-activity sensitive cells are treated with the rare saccharide to modify the function of the cells. A composition containing, as an active ingredient, a rare saccharide which is introduced into physiological-activity sensitive cells and has an effect of modifying the function of the cells. The cells are human cells. The composition is a functional food, a drug, or a cosmetic. The rare saccharide is a rare saccharide belonging to aldose and/or ketose. The aldose is D-allose, and the cells are selected from the group consisting of cancer-cell proliferation inhibitory activity sensitive cells and active-oxygen production inhibitory activity sensitive cells. The ketose is D-psicose, and the cells are selected from the group consisting of chemokine secretion inhibitory activity sensitive cells, microglia migration inhibitory activity sensitive cells, and hypoglycemic activity sensitive cells.

摘要翻译： 利用稀有糖类的生理活性的方法，其中用稀有糖类处理生理活性敏感性细胞以改变细胞的功能。 作为活性成分含有引入生理活性敏感性细胞的稀有糖类并具有改变细胞功能的作用的组合物。 细胞是人细胞。 组合物是功能性食品，药物或化妆品。 罕见的糖是属于醛糖和/或酮糖的稀有糖。 醛糖是D-丙氨酸，细胞选自癌细胞增殖抑制活性敏感细胞和活性氧生成抑制活性敏感细胞。 酮糖是D-psicose，细胞选自趋化因子分泌抑制活性敏感细胞，小胶质细胞迁移抑制活性敏感细胞和低血糖活性敏感细胞。

公开(公告)号：US07906487B2

公开(公告)日：2011-03-15

申请号：US10515018

申请日：2003-05-22

申请人： Ken Izumori ,  Masaaki Tokuda ,  Toshifumi Itano ,  Osamu Miyamoto ,  Toshihiko Ishida ,  Koji Murao ,  Taizo Tasaka ,  Gan Muneuchi ,  Fuminori Yamaguchi ,  Terukazu Tanaka ,  Masaaki Ueki ,  Kazuyuki Hirooka ,  Tomohiko Taminato ,  Mohammad Akram Hossain ,  Keiji Tsusaki ,  Takeo Takahashi ,  Mitsuhiro Nagata ,  Yutaka Ishida

发明人： Ken Izumori ,  Masaaki Tokuda ,  Toshifumi Itano ,  Osamu Miyamoto ,  Toshihiko Ishida ,  Koji Murao ,  Taizo Tasaka ,  Gan Muneuchi ,  Fuminori Yamaguchi ,  Terukazu Tanaka ,  Masaaki Ueki ,  Kazuyuki Hirooka ,  Tomohiko Taminato ,  Mohammad Akram Hossain ,  Keiji Tsusaki ,  Takeo Takahashi ,  Mitsuhiro Nagata ,  Yutaka Ishida

IPC分类号： A61K31/70004 ,  A61K31/70

CPC分类号： A61Q19/00 ,  A23L5/00 ,  A23L29/30 ,  A23L33/10 ,  A23L33/125 ,  A61K8/60 ,  A61K31/7004

摘要： A method of utilizing the physiological activity of a rare saccharide, wherein physiological-activity sensitive cells are treated with the rare saccharide to modify the function of the cells. A composition containing, as an active ingredient, a rare saccharide which is introduced into physiological-activity sensitive cells and has an effect of modifying the function of the cells. The cells are human cells. The composition is a functional food, a drug, or a cosmetic. The rare saccharide is a rare saccharide belonging to aldose and/or ketose. The aldose is D-allose, and the cells are selected from the group consisting of cancer-cell proliferation inhibitory activity sensitive cells and active-oxygen production inhibitory activity sensitive cells. The ketose is D-psicose, and the cells are selected from the group consisting of chemokine secretion inhibitory activity sensitive cells, microglia migration inhibitory activity sensitive cells, and hypoglycemic activity sensitive cells.

摘要翻译： 利用稀有糖类的生理活性的方法，其中用稀有糖类处理生理活性敏感性细胞以改变细胞的功能。 作为活性成分含有引入生理活性敏感性细胞的稀有糖类并具有改变细胞功能的作用的组合物。 细胞是人细胞。 组合物是功能性食品，药物或化妆品。 罕见的糖是属于醛糖和/或酮糖的稀有糖。 醛糖是D-丙氨酸，细胞选自癌细胞增殖抑制活性敏感细胞和活性氧生成抑制活性敏感细胞。 酮糖是D-psicose，细胞选自趋化因子分泌抑制活性敏感细胞，小胶质细胞迁移抑制活性敏感细胞和低血糖活性敏感细胞。