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8 条记录 (耗时 0.029 秒)

    Diagnostics for Aging-Related Dermatologic Disorders
    1.
    发明申请
    Diagnostics for Aging-Related Dermatologic Disorders 审中-公开
    老年相关皮肤病障碍诊断

    公开(公告)号：US20090170105A1

    公开(公告)日：2009-07-02

    申请号：US12268233

    申请日：2008-11-10

    申请人： Kenneth S. Kornman ,  Leon Wilkins

    发明人： Kenneth S. Kornman ,  Leon Wilkins

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/172

    摘要： The present invention provides methods for the early prediction of aging-related dermatologic conditions of including skin changes associated with intrinsic aging or skin damages caused by extrinsic aging such as photoaging. The present invention also provides kits for the early determination of the propensity to develop such disorder and conditions. The method consists of detecting the presence of one or more alleles of an IL-1 haplotype or pattern, specifically the IL-1RN (+2018) and the IL-1B (−511) loci. The presence of allele 2 at the IL-1RN (+2018) and the IL-1B (−511) loci indicates decreased risk for a early onset of aging related dermatologic conditions.

    摘要翻译： 本发明提供了用于早期预测老化相关皮肤病学条件的方法，其包括与内在衰老相关的皮肤变化或由诸如光老化的外在老化引起的皮肤损伤。 本发明还提供用于早期确定发展这种病症和病症的倾向的试剂盒。 该方法包括检测IL-1单倍型或模式，特别是IL-1RN（+2018）和IL-1B（-511）基因座的一个或多个等位基因的存在。 在IL-1RN（+2018）和IL-1B（-511）位点处的等位基因2的存在表明衰老相关皮肤病学早期发病风险降低。

    GENETIC MARKERS FOR WEIGHT MANAGEMENT AND METHODS OF USE THEREOF
    3.
    发明申请
    GENETIC MARKERS FOR WEIGHT MANAGEMENT AND METHODS OF USE THEREOF 审中-公开
    重量管理遗传标记及其使用方法

    公开(公告)号：US20100105038A1

    公开(公告)日：2010-04-29

    申请号：US12466614

    申请日：2009-05-15

    申请人： Colleen Draper ,  Leon Wilkins ,  Gary Breton ,  Louis Perusse

    发明人： Colleen Draper ,  Leon Wilkins ,  Gary Breton ,  Louis Perusse

    IPC分类号： C12Q1/68

    摘要： This application relates to methods and tests that allow for the establishment of personalized weight-loss programs for a subject based upon the subject's metabolic genotype in key metabolic genes. Kits and methods are disclosed for determining a subject's metabolic genotype, which may be used to select an appropriate therapeutic/dietary regimen or lifestyle recommendation based upon the likelihood of a subject's responsiveness to certain diets and activity levels. Such a personalized weight-loss program will have obvious benefits (e.g., yield better results in terms of weight loss and weight maintenance) over traditional weight-loss programs that do not take into account genetic information.

    摘要翻译： 本申请涉及允许基于主体代谢基因的代谢基因型为受试者建立个体化减肥计划的方法和测试。 公开了用于确定受试者的代谢基因型的试剂盒和方法，其可以用于基于受试者对某些饮食和活动水平的反应性的可能性来选择适当的治疗/饮食方案或生活方式推荐。 与没有考虑遗传信息的传统减肥计划相比，这样的个性化减肥计划将具有明显的益处（例如，在减肥和体重维持方面产生更好的结果）。

    GENETIC MARKER WEIGHT MANAGEMENT
    4.
    发明申请
    GENETIC MARKER WEIGHT MANAGEMENT 审中-公开
    遗传标记重量管理

    公开(公告)号：US20100098809A1

    公开(公告)日：2010-04-22

    申请号：US12466834

    申请日：2009-05-15

    申请人： Lewis H. Bender ,  Colleen Draper ,  Gary Breton ,  Leon Wilkins

    发明人： Lewis H. Bender ,  Colleen Draper ,  Gary Breton ,  Leon Wilkins

    IPC分类号： A23L1/307 ,  G06F19/00 ,  C12Q1/68

    摘要： A system and method for facilitating personal weight management based on genetic markers. Genetic samples can be analyzed and genotype patterns can be identified and provided to a user. Wellness information, including macronutrient requirements and exercise requirements, based on genotype patterns can be generated. Genotype patterns and wellness information can be stored, transmitted and displayed via computer networks and the internet. Existing third party diets, meal plans, and/or fitness programs can be recommended based on the genotype patterns. Individuals can use nutritional tracking software and/or exercise metric programs coupled with their genetic information to make adjustments to their diet and/or exercise to lose weight. Individuals can purchase nutrition products based on their genotype information.

    摘要翻译： 一种基于遗传标记促进个人体重管理的系统和方法。 可以分析遗传样品，并且可以鉴定并提供给用户的基因型模式。 可以生成基于基因型模式的健康信息，包括大量营养素需求和运动要求。 基因型模式和健康信息可以通过计算机网络和互联网进行存储，传输和显示。 可以根据基因型模式推荐现有的第三方饮食，膳食计划和/或健身计划。 个人可以使用营养跟踪软件和/或运动指标程序加上其遗传信息来调整他们的饮食和/或运动减肥。 个人可以根据其基因型信息购买营养产品。

    SKIN CARE COMPOSITIONS AND TREATMENTS
    7.
    发明申请
    SKIN CARE COMPOSITIONS AND TREATMENTS 审中-公开
    皮肤护理组合物和治疗

    公开(公告)号：US20070243158A1

    公开(公告)日：2007-10-18

    申请号：US11761893

    申请日：2007-06-12

    申请人： Vincent Ronfard ,  Alan Tuck ,  Leon Wilkins

    发明人： Vincent Ronfard ,  Alan Tuck ,  Leon Wilkins

    IPC分类号： A61Q19/08 ,  A61K45/00 ,  C12N5/06 ,  C12P1/00

    CPC分类号： C12N5/0629 ,  A61K8/99 ,  A61K35/12 ,  A61Q19/08 ,  C12N2502/094 ,  C12N2502/1323

    摘要： The invention is directed to compositions containing growth agents synthesized from cultured cells from skin. Skin cells such as keratinocytes and dermal fibroblasts are cultured in vitro in cell medium and in the course of culture the cultured cells synthesize and secrete agents into the cell medium. The medium containing agents are collected and incorporated into pharmaceutical or cosmetic preparations to treat an individual. The preparation is applied and has a rejuvenating effect on the cells and tissue.

    摘要翻译： 本发明涉及含有从皮肤培养的细胞合成的生长剂的组合物。 皮肤细胞如角质形成细胞和真皮成纤维细胞在细胞培养基中体外培养，培养过程中培养的细胞合成并将细胞分泌到细胞培养基中。 收集含有培养基的试剂，并将其并入药物或化妆品制剂中以治疗个体。 应用制剂，对细胞和组织具有恢复活力。