-
1.发明申请MODIFIED OLIGONUCLEOTIDES CONTAINING DIPHOSPHODIESTER INTERNUCLEOTIDE LINKAGES 失效含有二氢吡啶核苷酸连接的修饰的寡核苷酸公开(公告)号：US20080207551A1
公开(公告)日：2008-08-28
申请号：US11972254
申请日：2008-01-10
Applicant: Keykavous Parang , Yousef Ahamdibeni
Inventor： Keykavous Parang , Yousef Ahamdibeni
CPC classification number: C07H21/02
Abstract: The synthesis and biochemical utility of modified oligonucleotides containing diphosphodiester internucleotide linkages. The synthesis of these compounds was carried out using diphosphitylating reagents. Oligonucleotides containing diphosphate diester bridges wherein said oligonucleotides are synthesized via a solid-phase synthesis strategy to form modified oligonucleotides. Diphosphitylating, triphosphitylating, tetraphosphitylating, β-triphosphitylating, bifunctional diphosphitylating, bifunctional triphosphitylating, and bifunctional tetraphosphitylating reagents wherein, the phosphorus atoms are linked together through oxygen, sulfur, amino, or methylene groups and/or are substituted with chlorine, diisopropylamine and cyanoethoxy groups.
Abstract translation: 含有二磷酸二酯核苷酸键的修饰寡核苷酸的合成和生物化学实用性。 这些化合物的合成使用二磷酸化试剂进行。 含有二磷酸二酯桥的寡核苷酸，其中所述寡核苷酸通过固相合成策略合成以形成修饰的寡核苷酸。 双磷化，三磷酸化，四磷酸化，β-三磷酸化，双功能二磷酸化，双功能三磷酸化，双功能四磷酸化试剂，其中磷原子通过氧，硫，氨基或亚甲基连接在一起，和/或被氯，二异丙胺和氰基乙氧基取代 。
-
2.发明授权Polymer-bound phosphitylating reagents for the synthesis of organophosphorus compounds 失效用于合成有机磷化合物的聚合物结合的磷酸化试剂公开(公告)号：US08193384B2
公开(公告)日：2012-06-05
申请号：US11972254
申请日：2008-01-10
Applicant: Keykavous Parang , Yousef Ahamdibeni
Inventor： Keykavous Parang , Yousef Ahamdibeni
IPC: C07F9/48 , C07F9/22 , C07F9/24 , C07F9/26 , C07F9/141 , C07F9/142 , C07F9/143 , C07F9/144 , C07F9/145 , C07F9/146
CPC classification number: C07H21/02
Abstract: The synthesis and biochemical utility of modified oligonucleotides containing diphosphodiester internucleotide linkages. The synthesis of these compounds was carried out using diphosphitylating reagents. Oligonucleotides containing diphosphate diester bridges wherein said oligonucleotides are synthesized via a solid-phase synthesis strategy to form modified oligonucleotides. Diphosphitylating, triphosphitylating, tetraphosphitylating, β-triphosphitylating, bifunctional diphosphitylating, bifunctional triphosphitylating, and bifunctional tetraphosphitylating reagents wherein, the phosphorus atoms are linked together through oxygen, sulfur, amino, or methylene groups and/or are substituted with chlorine, diisopropylamine and cyanoethoxy groups.
Abstract translation: 含有二磷酸二酯核苷酸键的修饰寡核苷酸的合成和生物化学实用性。 这些化合物的合成使用二磷酸化试剂进行。 含有二磷酸二酯桥的寡核苷酸，其中所述寡核苷酸通过固相合成策略合成以形成修饰的寡核苷酸。 双磷化，三磷酸化，四磷酸化，三磷酸化，双官能二磷酸化，双功能三磷酸化，双功能四磷酸化试剂，其中磷原子通过氧，硫，氨基或亚甲基连接在一起，和/或被氯，二异丙胺和氰基乙氧基 团体
-
Search Results
2
records
(took 0.014 seconds)
