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    Composition for treating or preventing amyloid-related diseases comprising 4-O-methylhonokiol
    2.
    发明授权
    Composition for treating or preventing amyloid-related diseases comprising 4-O-methylhonokiol 有权
    用于治疗或预防包含4-O-甲基单烯醇的淀粉样蛋白相关疾病的组合物

    公开(公告)号：US08604087B2

    公开(公告)日：2013-12-10

    申请号：US13120818

    申请日：2009-09-25

    申请人： Ki Ho Kim ,  Ki Soo Kim ,  Young Heui Kim ,  Jin Guk Kim ,  Kyoung Tae Kim ,  Chang Sung Han ,  Sang iL Lee

    发明人： Ki Ho Kim ,  Ki Soo Kim ,  Young Heui Kim ,  Jin Guk Kim ,  Kyoung Tae Kim ,  Chang Sung Han ,  Sang iL Lee

    IPC分类号： A01N31/04 ,  A01N31/08

    CPC分类号： A61K31/085 ,  A23L2/52 ,  A23L33/105 ,  A61K31/05 ,  A61K36/575

    摘要： Disclosed is a composition for treating or preventing amyloid-related diseases including 4-O-methylhonokiol as an active ingredient. More specifically, a pharmaceutical composition including 4-O-methylhonokiol, which is effective for treating or preventing amyloid-related diseases such as Alzheimer's disease, cognitive disorder, defective memory, amyloidosis, etc. is disclosed. The inventors of the present disclosure have found out for the first time that 4-O-methylhonokiol inhibits the production of β-amyloid. It has been confirmed to be useful in treating or preventing amyloid-related diseases. Through animal tests including water maze test and passive avoidance test on mice, 4-O-methylhonokiol has been confirmed to be effective for amyloid-related diseases such as Alzheimer's disease, defective memory, cognitive disorder, and the like. It was further confirmed through acetylcholinesterase activity inhibition test using mouse brain cortex and hippocampus tissue that they are particularly effective in treating or preventing Alzheimer's disease among the amyloid-related diseases.

    摘要翻译： 公开了用于治疗或预防淀粉样蛋白相关疾病的组合物，包括4-O-甲基联苯甲醇作为活性成分。 更具体地说，公开了一种药物组合物，其包含对于治疗或预防淀粉样蛋白相关疾病如阿尔茨海默氏病，认知障碍，缺陷记忆，淀粉样变性等有效的4-O-甲基联苯甲醇。 本公开的发明人首次发现4-O-甲基联苯酚抑制β-淀粉样蛋白的产生。 已经证实可用于治疗或预防淀粉样蛋白相关疾病。 通过动物试验，包括水迷宫试验和小鼠被动回避试验，已证实4-O-甲基黑叶醇对淀粉样蛋白相关疾病如阿尔茨海默病，记忆缺陷，认知障碍等有效。 通过使用小鼠脑皮层和海马组织的乙酰胆碱酯酶活性抑制试验进一步证实，它们在淀粉样蛋白相关疾病中治疗或预防阿尔茨海默氏病方面特别有效。

    COMPOSITION FOR TREATING OR PREVENTING AMYLOID-RELATED DISEASES COMPRISING 4-O-METHYLHONOKIOL
    3.
    发明申请
    COMPOSITION FOR TREATING OR PREVENTING AMYLOID-RELATED DISEASES COMPRISING 4-O-METHYLHONOKIOL 有权
    用于治疗或预防包含4-O-甲基胆碱的与淀粉样相关疾病的组合物

    公开(公告)号：US20110207830A1

    公开(公告)日：2011-08-25

    申请号：US13120818

    申请日：2009-09-25

    申请人： Ki Ho Kim ,  Ki Soo Kim ,  Young Heui Kim ,  Jin Guk Kim ,  Kyoung Tae Kim ,  Chang Sung Han ,  Sang iL Lee

    发明人： Ki Ho Kim ,  Ki Soo Kim ,  Young Heui Kim ,  Jin Guk Kim ,  Kyoung Tae Kim ,  Chang Sung Han ,  Sang iL Lee

    IPC分类号： A61K31/075 ,  A61P25/28 ,  A61P25/00

    CPC分类号： A61K31/085 ,  A23L2/52 ,  A23L33/105 ,  A61K31/05 ,  A61K36/575

    摘要： Disclosed is a composition for treating or preventing amyloid-related diseases including 4-O-methylhonokiol as an active ingredient. More specifically, a pharmaceutical composition including 4-O-methylhonokiol, which is effective for treating or preventing amyloid-related diseases such as Alzheimer's disease, cognitive disorder, defective memory, amyloidosis, etc. is disclosed. The inventors of the present disclosure have found out for the first time that 4-O-methylhonokiol inhibits the production of β-amyloid. It has been confirmed to be useful in treating or preventing amyloid-related diseases. Through animal tests including water maze test and passive avoidance test on mice, 4-O-methylhonokiol has been confirmed to be effective for amyloid-related diseases such as Alzheimer's disease, defective memory, cognitive disorder, and the like. It was further confirmed through acetylcholinesterase activity inhibition test using mouse brain cortex and hippocampus tissue that they are particularly effective in treating or preventing Alzheimer's disease among the amyloid-related diseases.

    摘要翻译： 公开了用于治疗或预防淀粉样蛋白相关疾病的组合物，包括4-O-甲基联苯甲醇作为活性成分。 更具体地说，公开了一种药物组合物，其包含对于治疗或预防淀粉样蛋白相关疾病如阿尔茨海默氏病，认知障碍，缺陷记忆，淀粉样变性等有效的4-O-甲基联苯甲醇。 本公开的发明人首次发现4-O-甲基胡酮醇抑制β-淀粉样蛋白的产生。 已经证实可用于治疗或预防淀粉样蛋白相关疾病。 通过动物试验，包括水迷宫试验和小鼠被动回避试验，已证实4-O-甲基黑叶醇对淀粉样蛋白相关疾病如阿尔茨海默病，记忆缺陷，认知障碍等有效。 通过使用小鼠脑皮层和海马组织的乙酰胆碱酯酶活性抑制试验进一步证实，它们在淀粉样蛋白相关疾病中治疗或预防阿尔茨海默氏病方面特别有效。

    Data output device and semiconductor memory apparatus including the same
    8.
    发明授权
    Data output device and semiconductor memory apparatus including the same 有权
    数据输出装置和包括其的半导体存储装置

    公开(公告)号：US07911225B2

    公开(公告)日：2011-03-22

    申请号：US12482075

    申请日：2009-06-10

    申请人： Jeong Yoon Ahn ,  Ki Ho Kim

    发明人： Jeong Yoon Ahn ,  Ki Ho Kim

    IPC分类号： H03K17/16

    CPC分类号： H03K19/0005 ,  G11C7/1051 ,  G11C7/1057

    摘要： A data output device includes a pre-driver unit configured to control a driving force according to an impedance control signal and to drive output data using the driving force. The data output device includes a main-driver unit configured to control an impedance according to pull-up and pull-down resistance control codes having values that correspond to the impedance control signal provided to the pre-driver unit and to drive an output of the pre-driver unit by utilizing the controlled impedance.

    摘要翻译： 数据输出装置包括：预驱动器单元，被配置为根据阻抗控制信号来控制驱动力，并使用驱动力来驱动输出数据。 数据输出装置包括：主驱动器单元，被配置为根据具有与提供给预驱动器单元的阻抗控制信号相对应的值的上拉和下拉电阻控制代码控制阻抗，并驱动 预驱动单元利用受控阻抗。

    SYSTEM AND APPARATUS OF SEPARATING REMAINING POWER OF HULL
    9.
    发明申请
    SYSTEM AND APPARATUS OF SEPARATING REMAINING POWER OF HULL 有权
    分离船体剩余能力的系统和装置

    公开(公告)号：US20100272616A1

    公开(公告)日：2010-10-28

    申请号：US12708239

    申请日：2010-02-18

    申请人： Jae-Hoo JUNG ,  Young-Hwan Kim ,  Byung-Suk Park ,  Ki Ho Kim ,  Ho-Dong Kim

    发明人： Jae-Hoo JUNG ,  Young-Hwan Kim ,  Byung-Suk Park ,  Ki Ho Kim ,  Ho-Dong Kim

    IPC分类号： B01J19/00

    CPC分类号： B07B1/04 ,  B07B4/08 ,  G21F9/30 ,  Y10S422/903

    摘要： An apparatus and system for separating remaining powder of hulls includes a first remaining powder separating unit to be supplied with hulls of a spent nuclear fuel subjected to a high-temperature oxidation, and to include a first brush for separating remaining powder of the hulls; a hull alignment unit to be supplied with the hulls from the first remaining powder separating unit, and to align the hulls; a second remaining powder separating unit to be supplied with the aligned hulls from the hull alignment unit, and to include a second brush for separating remaining powder adhered on an inner peripheral surface of the hulls; and a third remaining powder separating unit to be supplied with the hulls from the second remaining powder separating unit, and to separate the remaining powder remaining on the inner/outer peripheral surface of the hulls by using air.

    摘要翻译： 用于分离船体的剩余粉末的装置和系统包括供给经受高温氧化的废核燃料的船体的第一剩余粉末分离单元，并且包括用于分离船体的剩余粉末的第一刷; 船体对准单元，其从第一剩余粉末分离单元提供船体，并对准船体; 第二剩余粉末分离单元，其从船体对准单元提供对准的船体，并且包括用于分离附着在船体的内周表面上的残留粉末的第二刷; 以及第三剩余粉末分离单元，从第二剩余粉末分离单元供给船体，并通过使用空气分离残留在船体的内外表面上的剩余粉末。

    Input buffer capable of reducing delay skew
    10.
    发明申请
    Input buffer capable of reducing delay skew 失效
    能够减少延迟偏移的输入缓冲器

    公开(公告)号：US20090251175A1

    公开(公告)日：2009-10-08

    申请号：US12291731

    申请日：2008-11-13

    申请人： Ki Ho Kim ,  Kang Seol Lee

    发明人： Ki Ho Kim ,  Kang Seol Lee

    IPC分类号： H03K3/00 ,  H03K5/12

    CPC分类号： H03K19/00323 ,  H03K19/018564

    摘要： An input buffer includes a delay compensation unit for combining (a) a first signal obtained by buffering an input signal using another signal, which is out of phase with the input signal, with (b) a second signal obtained by buffering the input signal using a reference voltage signal, to output a third signal.

    摘要翻译： 输入缓冲器包括延迟补偿单元，用于组合（a）通过使用与输入信号异相的另一信号来缓冲输入信号而获得的第一信号，（b）通过使用 参考电压信号，以输出第三信号。