公开(公告)号：US20190018922A1

公开(公告)日：2019-01-17

申请号：US16067687

申请日：2017-02-02

申请人： King Abdullah University of Science and Technology

发明人： Xin Gao ,  Hiroyuki Kuwahara ,  Meshari Saud Alazmi ,  Xuefeng Cui

IPC分类号： G06F19/12 ,  G06F19/26

摘要： The present invention relates to a method and system for dynamically analyzing, determining, predicting and displaying ranked suitable heterologous biosynthesis pathways for a specified host. The present invention addresses the problem of finding suitable pathways for the endogenous metabolism of a host organism because the efficacy of heterologous biosynthesis is affected by competing endogenous pathways. The present invention is called MRE (Metabolic Route Explorer), and it was conceived and developed to systematically and dynamically search for, determine, analyze, and display promising heterologous pathways while considering competing endogenous reactions in a given host organism.

公开(公告)号：US11342045B2

公开(公告)日：2022-05-24

申请号：US16067687

申请日：2017-02-02

申请人： King Abdullah University of Science and Technology

发明人： Xin Gao ,  Hiroyuki Kuwahara ,  Meshari Saud Alazmi ,  Xuefeng Cui

IPC分类号： G16B5/30 ,  G16B5/00 ,  G16B45/00 ,  G16B30/00 ,  G16B35/00 ,  G16C20/60

摘要： The present invention relates to a method and system for dynamically analyzing, determining, predicting and displaying ranked suitable heterologous biosynthesis pathways for a specified host. The present invention addresses the problem of finding suitable pathways for the endogenous metabolism of a host organism because the efficacy of heterologous biosynthesis is affected by competing endogenous pathways. The present invention is called MRE (Metabolic Route Explorer), and it was conceived and developed to systematically and dynamically search for, determine, analyze, and display promising heterologous pathways while considering competing endogenous reactions in a given host organism.