Methods and systems for delivering liquid substances to tissues surrounding body lumens
    1.
    发明授权
    Methods and systems for delivering liquid substances to tissues surrounding body lumens 有权
    将液体物质输送到体腔内的组织的方法和系统

    公开(公告)号:US07465298B2

    公开(公告)日:2008-12-16

    申请号:US10610790

    申请日:2003-06-30

    IPC分类号: A61M31/00

    摘要: Methods, systems, and apparatus for delivering drugs and other substances to extraluminal tissue surrounding a body lumen are described. Catheters are used to inject the drug or other substance intraluminally into tissue surrounding a stent or other luminal scaffold. The drug or other substance is injected in an amount sufficient to cause diffusion back through the tissue to the stent. An absorptive structure, reservoir, or the like, on the stent then absorbs excess drug as it passes from the luminal tissue. In this way, the stent is first loaded with drug. After time, as the stent becomes fully loaded and the tissue becomes depleted, drug will be begin to flow back from the stent into the surrounding luminal tissue.

    摘要翻译: 描述了用于将药物和其他物质递送到体腔周围的外部组织的方法,系统和装置。 导管用于将药物或其他物质内腔注射到支架或其他管腔支架周围的组织中。 药物或其他物质的注射量足以引起扩散通过组织到支架。 支架上的吸收结构,储存器等在从管腔组织通过时吸收过量的药物。 以这种方式,支架首先装载药物。 随着时间的推移,当支架变得完全负载并且组织耗尽时,药物将开始从支架流回到周围的管腔组织中。