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公开(公告)号：US20090069414A1
公开(公告)日：2009-03-12
申请号：US11977683
申请日：2007-10-25
申请人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, JR. , Hans M. Geyet , Mary E. Myers , Eric J. Whitacre , Harold H. Schmitz
发明人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, JR. , Hans M. Geyet , Mary E. Myers , Eric J. Whitacre , Harold H. Schmitz
IPC分类号： A61K31/353
CPC分类号： C07H17/06 , A23G1/32 , A23G3/36 , A23K20/111 , A23K50/40 , A61K9/2018 , A61K9/2068 , A61K9/4858 , A61K31/353 , A61K31/7048 , A61K36/185 , A61K45/06 , C07D311/32 , C07D311/62 , C07D311/64 , C11B5/0035 , A61K2300/00
摘要： This invention relates to compositions comprising epicatechin and method of use of such compositions for inducing vasodilation of blood vessels in humans and veterinary animals.
摘要翻译： 本发明涉及包含表儿茶素的组合物及其用于诱导人体和兽医动物血管血管扩张的方法。
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公开(公告)号：US20080188550A1
公开(公告)日：2008-08-07
申请号：US11977496
申请日：2007-10-25
申请人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk , Hans M. Geyet , Mary E. Myers , Eric J. Whitacre , Harold H. Schmitz
发明人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk , Hans M. Geyet , Mary E. Myers , Eric J. Whitacre , Harold H. Schmitz
IPC分类号： A61K31/353 , A61P29/00
CPC分类号： C07H17/06 , A23G1/32 , A23G3/36 , A23K20/111 , A23K50/40 , A61K9/2018 , A61K9/2068 , A61K9/4858 , A61K31/353 , A61K31/7048 , A61K36/185 , A61K45/06 , C07D311/32 , C07D311/62 , C07D311/64 , C11B5/0035 , A61K2300/00
摘要： This invention relates to methods of treating inflammation comprising administering to a subject in need thereof a composition comprising the inventive compounds described herein.
摘要翻译： 本发明涉及治疗炎症的方法，包括向有需要的受试者施用包含本文所述的本发明化合物的组合物。
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公开(公告)号：US08541045B2
公开(公告)日：2013-09-24
申请号：US11639129
申请日：2006-12-14
申请人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
发明人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
IPC分类号： A23G1/00
CPC分类号： A23G1/48 , A21D2/36 , A21D13/80 , A23G1/002 , A23G1/02 , A23G1/305 , A23G1/56 , A23G3/48 , A23G2200/14 , A23K50/42 , A23K50/48 , A23L27/11 , A23L33/105 , A23V2002/00 , A23V2250/2132
摘要： Cocoa components having enhanced levels of cocoa polyphenols, processes for producing the cocoa components while conserving a significant amount of the cocoa polyphenols, compositions containing the cocoa components or the cocoa polyphenols, and methods of using the cocoa components or the cocoa polyphenols for improving the health of a mammal are described. The cocoa components include partially and fully defatted cocoa solids, cocoa nibs and fractions derived therefrom, cocoa polyphenol extracts, cocoa butter, chocolate liquors, and mixtures thereof. The invention provides processes for extracting fat from cocoa beans and for otherwise processing cocoa beans to yield a cocoa component having conserved concentrations of polyphenols relative to the starting materials.
摘要翻译： 可可组分具有增加的可可多元酚水平，生产可可组分的过程同时保留大量的可可多元酚，含有可可组分或可可多元酚的组合物，以及使用可可组分或可可多元酚改善健康的方法 描述了哺乳动物。 可可组分包括部分和完全脱脂的可可固体，可可可可及其衍生的级分，可可多酚提取物，可可脂，巧克力液及其混合物。 本发明提供从可可豆中提取脂肪以及否则加工可可豆以产生相对于起始原料具有保守的多酚浓度的可可组分的方法。
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公开(公告)号：US07678407B2
公开(公告)日：2010-03-16
申请号：US11926994
申请日：2007-10-29
申请人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
发明人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
IPC分类号： A23G1/00
CPC分类号： A23G1/48 , A21D2/36 , A21D13/80 , A23G1/002 , A23G1/02 , A23G1/305 , A23G1/56 , A23G3/48 , A23G2200/14 , A23K50/42 , A23K50/48 , A23L27/11 , A23L33/105 , A23V2002/00 , A23V2250/2132
摘要： Cocoa components having enhanced levels of cocoa polyphenols, processes for producing the cocoa components while conserving a significant amount of the cocoa polyphenols, compositions containing the cocoa components or the cocoa polyphenols, and methods of using the cocoa components or the cocoa polyphenols for improving the health of a mammal are described. The cocoa components include partially and fully defatted cocoa solids, cocoa nibs and fractions derived therefrom, cocoa polyphenol extracts, cocoa butter, chocolate liquors, and mixtures thereof. The invention provides processes for extracting fat from cocoa beans and for otherwise processing cocoa beans to yield a cocoa component having conserved concentrations of polyphenols relative to the starting materials.
摘要翻译： 可可组分具有增加的可可多元酚水平，生产可可组分的过程同时保留大量的可可多元酚，含有可可组分或可可多元酚的组合物，以及使用可可组分或可可多元酚改善健康的方法 描述了哺乳动物。 可可组分包括部分和完全脱脂的可可固体，可可可可及其衍生的级分，可可多酚提取物，可可脂，巧克力液及其混合物。 本发明提供从可可豆中提取脂肪以及否则加工可可豆以产生相对于起始原料具有保守的多酚浓度的可可组分的方法。
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公开(公告)号：US06599553B2
公开(公告)日：2003-07-29
申请号：US09992932
申请日：2001-11-05
申请人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
发明人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
IPC分类号： C07D31178
CPC分类号： A23G1/48 , A21D2/36 , A21D2/364 , A21D13/80 , A23G1/02 , A23G1/06 , A23G1/305 , A23G1/56 , A23G3/48 , A23G2200/00 , A23G2200/14 , A23K50/42 , A23K50/48 , A23L7/122 , A23L7/126 , A23L7/17 , A23L7/178 , A23L7/196 , A23L9/10 , A23L19/09 , A23L33/10 , A23L33/105 , A23V2002/00 , C11B1/04 , C11B1/06 , A23V2250/2132
摘要： A dry drink mix which is rich in cocoa polyphenols such as catechin, epicatechin, and cocoa procyanidins contains a cocoa polyphenol rich cocoa powder, an alkalized cocoa powder, and a sweetener. The dry mix contains other conventional ingredients such as vanillin an emulsifier. A chocolate flavored drink can be prepared from the dry drink mix by adding milk, for example a low fat milk. The cocoa polyphenol rich cocoa powder is prepared from non-roasted cocoa beans or blends thereof having a fermentation factor of 275 less, i.e., slaty and/or purple cocoa beans. The alkalized cocoa powder is prepared from roasted cocoa beans.
摘要翻译： 富含可可多酚如儿茶素，表儿茶素和可可原花青素的干饮料混合物含有可可多酚可可粉，碱化可可粉和甜味剂。 干混合物含有其他常规成分，如香草醛和乳化剂。 可以通过加入牛奶（例如低脂牛奶）从干混饮料制备巧克力风味饮料。 可可多元酚丰富的可可粉由发酵因子为275的非焙烤可可豆或其混合物制成，即发酵因子为275以下，即鳞状和/或紫色可可豆。 碱化的可可粉由焙炒的可可豆制成。
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公开(公告)号：US20080268133A1
公开(公告)日：2008-10-30
申请号：US11926994
申请日：2007-10-29
申请人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk , Hans M. Gever , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone , Harold H. Schmitz
发明人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk , Hans M. Gever , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone , Harold H. Schmitz
IPC分类号： A23G1/00
CPC分类号： A23G1/48 , A21D2/36 , A21D13/80 , A23G1/002 , A23G1/02 , A23G1/305 , A23G1/56 , A23G3/48 , A23G2200/14 , A23K50/42 , A23K50/48 , A23L27/11 , A23L33/105 , A23V2002/00 , A23V2250/2132
摘要： Cocoa components having enhanced levels of cocoa polyphenols, processes for producing the cocoa components while conserving a significant amount of the cocoa polyphenols, compositions containing the cocoa components or the cocoa polyphenols, and methods of using the cocoa components or the cocoa polyphenols for improving the health of a mammal are described. The cocoa components include partially and fully defatted cocoa solids, cocoa nibs and fractions derived therefrom, cocoa polyphenol extracts, cocoa butter, chocolate liquors, and mixtures thereof. The invention provides processes for extracting fat from cocoa beans and for otherwise processing cocoa beans to yield a cocoa component having conserved concentrations of polyphenols relative to the starting materials.
摘要翻译： 可可组分具有增加的可可多元酚水平，生产可可组分的过程同时保留大量的可可多元酚，含有可可组分或可可多元酚的组合物，以及使用可可组分或可可多元酚改善健康的方法 描述了哺乳动物。 可可组分包括部分和完全脱脂的可可固体，可可可可及其衍生的级分，可可多酚提取物，可可脂，巧克力液及其混合物。 本发明提供从可可豆中提取脂肪以及否则加工可可豆以产生相对于起始原料具有保守的多酚浓度的可可组分的方法。
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公开(公告)号：US06558713B2
公开(公告)日：2003-05-06
申请号：US09981529
申请日：2001-10-16
申请人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
发明人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
IPC分类号： A61K3578
CPC分类号： A23G1/48 , A21D2/36 , A21D2/364 , A21D13/80 , A23G1/02 , A23G1/06 , A23G1/305 , A23G1/56 , A23G3/48 , A23G2200/00 , A23G2200/14 , A23K50/42 , A23K50/48 , A23L7/122 , A23L7/126 , A23L7/17 , A23L7/178 , A23L7/196 , A23L9/10 , A23L19/09 , A23L33/10 , A23L33/105 , A23V2002/00 , C11B1/04 , C11B1/06 , A23V2250/2132
摘要： Cocoa components having enhanced levels of cocoa polyphenols, processes for producing the cocoa components while conserving a significant amount of the cocoa polyphenols, compositions containing the cocoa components or the cocoa polyphenols, and methods of using the cocoa components or the cocoa polyphenols for improving the health of a mammal are described. The cocoa components include partially and fully defatted cocoa solids, cocoa nibs and fractions derived therefrom, cocoa polyphenol extracts, cocoa butter, chocolate liquors, and mixtures thereof. The invention provides processes for extracting fat from cocoa beans and for otherwise processing cocoa beans to yield a cocoa component having conserved concentrations of polyphenols relative to the starting materials.
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公开(公告)号：US07968140B2
公开(公告)日：2011-06-28
申请号：US10436025
申请日：2003-05-12
申请人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
发明人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
IPC分类号： A23G1/00
CPC分类号： A23G1/48 , A21D2/36 , A21D13/80 , A23G1/002 , A23G1/02 , A23G1/305 , A23G1/56 , A23G3/48 , A23G2200/14 , A23K50/42 , A23K50/48 , A23L27/11 , A23L33/105 , A23V2002/00 , A23V2250/2132
摘要： Cocoa components having enhanced levels of cocoa polyphenols, processes for producing the cocoa components while conserving a significant amount of the cocoa polyphenols, compositions containing the cocoa components or the cocoa polyphenols, and methods of using the cocoa components or the cocoa polyphenols for improving the health of a mammal are described. The cocoa components include partially and fully defatted cocoa solids, cocoa nibs and fractions derived therefrom, cocoa polyphenol extracts, cocoa butter, chocolate liquors, and mixtures thereof. The invention provides processes for extracting fat from cocoa beans and for otherwise processing cocoa beans to yield a cocoa component having conserved concentrations of polyphenols relative to the starting materials.
摘要翻译： 可可组分具有增加的可可多元酚水平，生产可可组分的过程同时保留大量的可可多元酚，含有可可组分或可可多元酚的组合物，以及使用可可组分或可可多元酚改善健康的方法 描述了哺乳动物。 可可组分包括部分和完全脱脂的可可固体，可可可可及其衍生的级分，可可多酚提取物，可可脂，巧克力液及其混合物。 本发明提供从可可豆中提取脂肪以及否则加工可可豆以产生相对于起始原料具有保守的多酚浓度的可可组分的方法。
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公开(公告)号：US20090117072A1
公开(公告)日：2009-05-07
申请号：US11978127
申请日：2007-10-26
申请人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, JR. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , Harold H. Schmitz
发明人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, JR. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , Harold H. Schmitz
IPC分类号： A61K31/353 , A61K31/765 , A61P43/00
CPC分类号： C07H17/06 , A23G1/32 , A23G3/36 , A23K20/111 , A23K50/40 , A61K9/2018 , A61K9/2068 , A61K9/4858 , A61K31/353 , A61K31/7048 , A61K36/185 , A61K45/06 , C07D311/32 , C07D311/62 , C07D311/64 , C11B5/0035 , A61K2300/00
摘要： This invention relates to a method of therapeutic or prophylactic treatment of periodontal disease comprising administering to a subject in need thereof epicatechin and/or catechin and/or a polymeric compound of formula An. Also disclosed and claimed is an article of manufacture comprising the above compounds packaged within a container with instructions for use thereof.
摘要翻译： 本发明涉及治疗或预防性治疗牙周疾病的方法，包括向有需要的受试者施用表儿茶素和/或儿茶素和/或式A的聚合物。 还公开并要求保护的是包含在容器内包装的上述化合物的制品，其具有使用说明书。
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10.发明授权Cocoa components, edible products having enriched polyphenol content, methods of making same and medical uses 有权可可成分，富含多酚含量的食用产品，制作方法和医疗用途公开(公告)号：US06312753B1
公开(公告)日：2001-11-06
申请号：US09254353
申请日：1999-08-09
申请人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
发明人： Kirk S. Kealey , Rodney M. Snyder , Leo J. Romanczyk, Jr. , Hans M. Geyer , Mary E. Myers , Eric J. Whitacre , John F. Hammerstone, Jr. , Harold H. Schmitz
IPC分类号： C07D31178
CPC分类号： A23G1/30 , A21D2/36 , A21D2/364 , A21D13/80 , A23G1/02 , A23G1/04 , A23G1/06 , A23G1/305 , A23G1/36 , A23G1/48 , A23G1/56 , A23G3/48 , A23G2200/00 , A23G2200/14 , A23K50/42 , A23K50/48 , A23L3/349 , A23L3/3544 , A23L7/122 , A23L7/126 , A23L7/17 , A23L7/178 , A23L7/196 , A23L9/10 , A23L19/09 , A23L33/10 , A23L33/105 , A23V2002/00 , C11B1/04 , C11B1/06 , A23V2250/2132
摘要： Cocoa components having enhanced levels of cocoa polyphenols, processes for producing the cocoa components while conserving a significant amount of the cocoa polyphenols, compositions containing the cocoa components or the cocoa polyphenols, and methods of using the cocoa components or the cocoa polyphenols for improving the health of a mammal are described. The cocoa components include partially and fully defatted cocoa solids, cocoa nibs and fractions derived therefrom, cocoa polyphenol extracts, cocoa butter, chocolate liquors, and mixtures thereof. The invention provides processes for extracting fat from cocoa beans and for otherwise processing cocoa beans to yield a cocoa component having conserved concentrations of polyphenols relative to the starting materials.
摘要翻译： 可可组分具有增加的可可多元酚水平，生产可可组分的过程同时保留大量的可可多元酚，含有可可组分或可可多元酚的组合物，以及使用可可组分或可可多元酚改善健康的方法 描述了哺乳动物。 可可组分包括部分和完全脱脂的可可固体，可可可可及其衍生的级分，可可多酚提取物，可可脂，巧克力液及其混合物。 本发明提供从可可豆中提取脂肪以及否则加工可可豆以产生相对于起始原料具有保守的多酚浓度的可可组分的方法。
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