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公开(公告)号:US5595989A
公开(公告)日:1997-01-21
申请号:US367648
申请日:1995-01-03
申请人: Knud E. Andersen , Uffe B. Olsen , Hans Petersen , Frederik Gr.o slashed.nvald , Ursula Sonnewald , Tine K. J.o slashed.rgensen , Henrik S. Andersen
发明人: Knud E. Andersen , Uffe B. Olsen , Hans Petersen , Frederik Gr.o slashed.nvald , Ursula Sonnewald , Tine K. J.o slashed.rgensen , Henrik S. Andersen
IPC分类号: A61K31/00 , A61K31/4427 , A61K31/4433 , A61K31/445 , A61K31/535 , A61K31/54 , A61K31/55 , A61P1/00 , A61P11/00 , A61P17/00 , A61P23/00 , A61P25/04 , A61P29/00 , A61P43/00 , C07D207/10 , C07D211/60 , C07D211/78 , C07D401/06 , C07D403/06 , C07D405/00 , C07D407/06 , C07D409/06 , C07D413/06 , C07D417/06
CPC分类号: C07D401/06 , C07D211/60 , C07D211/78 , C07D409/06 , C07D413/06 , C07D417/06
摘要: The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.