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    Pericardium Fixation Concepts of Epicardium Pacing Leads and Tools
    1.
    发明申请
    Pericardium Fixation Concepts of Epicardium Pacing Leads and Tools 有权
    心包起搏导联和工具的心包固定概念

    公开(公告)号：US20070255376A1

    公开(公告)日：2007-11-01

    申请号：US11380234

    申请日：2006-04-26

    申请人： Koen Michels ,  Jean-Luc Jansens ,  Victor Duysens ,  Paulus Adams ,  Paulus Van Venrooij ,  Markus Lazeroms ,  Fredric Lindemans

    发明人： Koen Michels ,  Jean-Luc Jansens ,  Victor Duysens ,  Paulus Adams ,  Paulus Van Venrooij ,  Markus Lazeroms ,  Fredric Lindemans

    IPC分类号： A61N1/00

    CPC分类号： A61N1/0587

    摘要： Certain aspects of the disclosure pertain to methods and apparatus for providing positive fixation of medical components to a portion of incised pericardial tissue. Accordingly, a resilient member protrudes through an incision in the pericardium and produces a positive biasing force to adjacent pericardial tissue against a side surface of an attached body structure. The resilient member can optionally be compressed during implantation and then relaxed to thereafter provide the positive biasing force. Diverse medical components can thus be safely and reliably chronically deployed into the pericardial space, including without limitation, cardiac sensing/pacing, defibrillation and/or cardioversion electrodes, mechanical and/or metabolic sensors and the like. More than one body structure can be linked to a single medical electrical lead and the medical components can couple within and/or upon a portion of the body structure, the resilient member, and the lead in myriad configurations.

    摘要翻译： 本公开的某些方面涉及用于向切开的心包组织的一部分提供医疗部件的正面固定的方法和装置。 因此，弹性构件通过心包中的切口突出，并且相对于附接体结构的侧表面产生相邻心包组织的正偏置力。 弹性构件可以可选地在植入期间被压缩，然后松弛，之后提供正的偏压力。 因此，不同的医疗部件可以安全可靠地长期地部署到心包空间中，包括但不限于心脏感测/起搏，除颤和/或心脏复律电极，机械和/或代谢传感器等。 多个主体结构可以连接到单个医疗电引线，并且医疗部件可以在各种构造中联接在身体结构，弹性构件和引线的一部分内和/或之内。

    Pericardium fixation concepts of epicardium pacing leads and tools
    2.
    发明授权
    Pericardium fixation concepts of epicardium pacing leads and tools 有权
    心包起搏导联和工具的心包固定概念

    公开(公告)号：US08244379B2

    公开(公告)日：2012-08-14

    申请号：US11380234

    申请日：2006-04-26

    申请人： Koen Michels ,  Jean-Luc Jansens ,  Victor Duysens ,  Paulus G. Adams ,  Paulus Van Venrooij ,  Markus J. C. Lazeroms ,  Fredric W. Lindemans

    发明人： Koen Michels ,  Jean-Luc Jansens ,  Victor Duysens ,  Paulus G. Adams ,  Paulus Van Venrooij ,  Markus J. C. Lazeroms ,  Fredric W. Lindemans

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0587

    摘要： Certain aspects of the disclosure pertain to methods and apparatus for providing positive fixation of medical components to a portion of incised pericardial tissue. Accordingly, a resilient member protrudes through an incision in the pericardium and produces a positive biasing force to adjacent pericardial tissue against a side surface of an attached body structure. The resilient member can optionally be compressed during implantation and then relaxed to thereafter provide the positive biasing force. Diverse medical components can thus be safely and reliably chronically deployed into the pericardial space, including without limitation, cardiac sensing/pacing, defibrillation and/or cardioversion electrodes, mechanical and/or metabolic sensors and the like. More than one body structure can be linked to a single medical electrical lead and the medical components can couple within and/or upon a portion of the body structure, the resilient member, and the lead in myriad configurations.

    摘要翻译： 本公开的某些方面涉及用于向切开的心包组织的一部分提供医疗部件的正面固定的方法和装置。 因此，弹性构件通过心包中的切口突出，并且相对于附接体结构的侧表面产生相邻心包组织的正偏置力。 弹性构件可以可选地在植入期间被压缩，然后松弛，之后提供正的偏压力。 因此，不同的医疗部件可以安全可靠地长期地部署到心包空间中，包括但不限于心脏感测/起搏，除颤和/或心脏复律电极，机械和/或代谢传感器等。 多个主体结构可以连接到单个医疗电引线，并且医疗部件可以在各种构造中联接在身体结构，弹性构件和引线的一部分内和/或之内。

    Medical electrical lead and introducer system
    5.
    发明授权
    Medical electrical lead and introducer system 有权

    公开(公告)号：US06278897B1

    公开(公告)日：2001-08-21

    申请号：US09204314

    申请日：1998-12-03

    申请人： Jean J. G. Rutten ,  Karel Smits ,  Nicolaas Lokhoff ,  Paulus Van Venrooij

    发明人： Jean J. G. Rutten ,  Karel Smits ,  Nicolaas Lokhoff ,  Paulus Van Venrooij

    IPC分类号： A61N105

    CPC分类号： A61N1/056 ,  A61M25/0668

    摘要： A medical electrical lead and introducer system. The lead is a single pass, dual chamber lead, which features in one embodiment an atrial tine. The introducer system is particularly designed for introduction of single pass, dual chamber lead which has an atrial tine. The introducer system facilitates the introduction of a such lead into a patient's heart while safeguarding the tine from damage due to kinking during lead positioning. The lead is a single pass lead which features an atrial tine while the introducer system is particularly designed for introduction of a such lead into a patient's heart so as to safeguard the tine from damage due to kinking during lead positioning. The lead is designed so as to electrically couple both the atrium and the ventricular chambers of the heart. The lead generally features several lengths each having differing stiffness as well as a pre-formed bend. The lead also features a atrial tine having an electrode at the tip. Due to the relatively fragile as well as difficult to maneuver lead, an introducer system is also disclosed. The introducer system is particularly designed to introduce such a lead. In use a removable tubing split element surrounds the atrial tine area of the lead while it is disposed through the introducer sheath, the split element both blocks the tine from lateral movement and fills up the space between the lead body and the introducer, thereby preventing blood leakage through the introducer. The element also has a longitudinal split for receiving the atrial tine while holding it against transverse movement when the lead is being repositioned. After optimal positioning of the lead, the tubing split element is withdrawn, and then the introducer is withdrawn. The tubing split element is a generally cylindrical piece of TEFLON, here called a tube split element, or just a “tube split”, is positioned around the lead body in the atrial tine area. The tube split element has a thickness which substantially fills the radial gap between the smaller diameter lead body and the introducer inner cylindrical wall, and has a longitudinal separation, or split, which accommodates the atrial tine, thereby permitting the tine to extend longitudinally but not transversely. The tubing split element is preferably mounted on the lead at the time of lead assembly. It has a length sufficient to extend proximally out of the introducer so that it can be withdrawn, and has a longitudinal tear line whereby the element can be separated and removed from the lead after final positioning of the lead.

    Medical electrical right atrium and coronary sinus lead
    6.
    发明授权
    Medical electrical right atrium and coronary sinus lead 失效
    医疗电气右心房和冠状窦导联

    公开(公告)号：US6070104A

    公开(公告)日：2000-05-30

    申请号：US980438

    申请日：1997-11-28

    申请人： Douglas Hine ,  Nicolaas Lokhoff ,  Paulus Van Venrooij ,  Arnoldus Bakels

    发明人： Douglas Hine ,  Nicolaas Lokhoff ,  Paulus Van Venrooij ,  Arnoldus Bakels

    IPC分类号： A61N1/05

    CPC分类号： A61N1/056

    摘要： A transvenous lead specifically designed for multi-chamber electrical stimulation or sensing. In a first embodiment the lead features one or more electrodes for communication with the right atrium as well as one or more electrodes for communication with either or both of the left chambers of the heart. The lead further features structures to simultaneously bring the first electrode into contact with a first chamber, such as the right atrial wall and the second electrode into contact with a particular portion of the coronary sinus wall, to electrically access the left atrium or ventricle. In the preferred embodiment the lead body has varying flex or stiffness characteristics along its length between each of the electrodes. The relation of the varying flex or stiffness characteristics along the lead body length as well as the various linear placements of the electrodes along the lead body length function to simultaneously bring the first electrode into contact with a first desired portion of the heart, such as the right atrial wall, and the second electrode into contact with a second desired portion of the heart, such as a portion of the coronary sinus wall.

    摘要翻译： 专为多室电刺激或感应设计的经静脉导管。 在第一实施例中，引线具有用于与右心房连通的一个或多个电极以及用于与心脏的左腔室中的一个或两者连通的一个或多个电极。 引线还具有结构，以同时使第一电极与诸如右心房壁和第二电极的第一腔室接触以与冠状静脉窦壁的特定部分接触以电接入左心房或心室。 在优选实施例中，引线主体沿其长度在每个电极之间具有变化的弯曲或刚度特性。 沿着引线主体长度的变化的弯曲或刚度特性以及电极沿引线体长度的各种线性放置的关系用于同时使第一电极与心脏的第一所需部分接触，例如 右心房壁和第二电极与心脏的第二期望部分接触，例如冠状窦壁的一部分。

    Medical electrical lead
    7.
    发明授权
    Medical electrical lead 失效
    医用电线

    公开(公告)号：US5991668A

    公开(公告)日：1999-11-23

    申请号：US936991

    申请日：1997-09-25

    申请人： Robert Leinders ,  Nicolaas Lokhoff ,  Paulus Van Venrooij ,  Arnoldus Bakels

    发明人： Robert Leinders ,  Nicolaas Lokhoff ,  Paulus Van Venrooij ,  Arnoldus Bakels

    IPC分类号： A61N1/05 ,  A61N1/04

    CPC分类号： A61N1/057 ,  A61N2001/0585

    摘要： A transvenous lead specifically designed for coronary sinus implantation. In the preferred embodiment the lead features an electrode which is eccentricity placed along the lead body. Disposed on the opposite side of the lead body is a tine-like member to push or maintain the electrode into contact with the vessel wall. Because the electrode and tine-like member do not entirely block the cross sectional area of the vessel, blood flow through the vessel is not impeded. Through such a configuration electrical stimulation with the tissue comprising the left side of the heart may be accomplished. In alternative embodiments other mechanisms besides tine-like member are used to maintain the contact of the electrode with the vessel wall. In a still further alternative embodiment the eccentricity disposed electrode is positioned instead upon the tip of the tine.

    摘要翻译： 专门设计用于冠状窦植入的静脉导管。 在优选实施例中，引线具有沿引线本体放置的偏心的电极。 设置在引线体的相反侧的是齿状部件，以推动或保持电极与血管壁接触。 因为电极和齿状构件不完全阻挡血管的横截面积，所以不会妨碍通过血管的血流。 通过这样的配置，可以实现包括心脏左侧的组织的电刺激。 在替代实施例中，使用除了类似元件之外的其它机构来保持电极与血管壁的接触。 在又一替代实施例中，偏心设置电极被替代地置于尖端。

    Implantable cortical neural lead and method
    8.
    发明授权
    Implantable cortical neural lead and method 有权
    植入式皮层神经铅和方法

    公开(公告)号：US07107104B2

    公开(公告)日：2006-09-12

    申请号：US10448645

    申请日：2003-05-30

    申请人： Yves Keravel ,  Jean Paul N'Guyen ,  Paulus Van Venrooij ,  Frans L. H. Gielen ,  Thomas E. Cross, Jr.

    发明人： Yves Keravel ,  Jean Paul N'Guyen ,  Paulus Van Venrooij ,  Frans L. H. Gielen ,  Thomas E. Cross, Jr.

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0531 ,  A61N1/0553

    摘要： A neural lead and method of treating neurological disorders by stimulation of the cerebral cortex of the brain is provided. The lead is designed for reduction of strain between the lead body and the lead paddle caused by the position of the lead body above the cranium and the lead paddle beneath the cranium. The lead is also designed to include a two dimensional chronic electrode array for better stimulation coverage of the target area of the cerebral cortex. A method of treating a neurological disorder by stimulating the cerebral cortex is also presented.

    摘要翻译： 提供了通过刺激脑的大脑皮层治疗神经障碍的神经引导和方法。 引线设计用于减少引线主体和引线板之间的引线引起的引线体在颅骨上方的位置和颅骨下方的引导片之间的应变。 该引线还被设计成包括用于更好地刺激大脑皮层目标区域的覆盖的二维慢性电极阵列。 还提出了通过刺激大脑皮质治疗神经障碍的方法。

    Single pass medical electrical lead
    9.
    发明授权
    Single pass medical electrical lead 失效
    单程医用电线

    公开(公告)号：US5849032A

    公开(公告)日：1998-12-15

    申请号：US937444

    申请日：1997-09-25

    申请人： Paulus Van Venrooij

    发明人： Paulus Van Venrooij

    IPC分类号： A61N1/05

    CPC分类号： A61N1/056

    摘要： A single pass medical electrical lead featuring an atrial wall wedging mechanism which will permit the atrial electrodes to be positioned directly against the right atrial wall. In the preferred embodiment the atrial wall wedging mechanism comprises an extendible finger which may be used to wedge the lead body in the region where the inferior vena cava enters the right atrium and the right atrium empties through the tricuspid valve into the right ventricle. Through such wedging, the atrial electrodes may be caused to be positioned directly against the right atrium wall without causing excessive pressure to be communicated to the distal tip of the lead.

    摘要翻译： 单通道医用电气导线，具有心房壁楔入机构，允许心房电极直接抵靠右心房壁。 在优选实施例中，心房壁楔入机构包括可伸展的手指，其可以用于在下腔静脉进入右心房的区域中楔入引线体，并且右心房通过三尖瓣排空到右心室中。 通过这样的楔入，可以使心房电极直接抵靠右心房壁定位，而不会导致过大的压力与铅的远端连通。

    Minimally invasive medical electrical lead
    10.
    发明授权
    Minimally invasive medical electrical lead 失效
    微创医疗电子铅

    公开(公告)号：US5716392A

    公开(公告)日：1998-02-10

    申请号：US583358

    申请日：1996-01-05

    申请人： Ivan Bourgeois ,  Noud Bakels ,  Paulus Van Venrooij

    发明人： Ivan Bourgeois ,  Noud Bakels ,  Paulus Van Venrooij

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0502 ,  A61N1/0587

    摘要： A medical electrical lead which may be introduced using a thorascope and is used to electrically stimulate tissue, such as a heart. The lead of the present invention has a "ski-shaped" needle, a strand of between 1-5 cm. attached to the needle, an electrode attached to the strand, and an insulated lead body attached to the electrode. In addition, a test wire is also attached to the needle to permit the electrical characteristics of tissue to be ascertained before the lead is fully inserted. In an alternate embodiment the strand may feature a fixation helix. Due to the shape of the needle and the relatively short strand, the lead is particularly suitable for implantation to a heart using minimally invasive techniques, such as through a trocar.

    摘要翻译： 可以使用胸腔引入并用于电刺激诸如心脏的组织的医用电引线。 本发明的引线具有“滑雪形”针，1-5cm之间的线。 连接到针上，附接到股线的电极和连接到电极的绝缘引线体。 此外，测试线也附接到针上，以允许在引线完全插入之前确定组织的电特性。 在替代实施例中，股线可以具有固定螺旋。 由于针的形状和相对短的股线，铅特别适用于使用微创技术（例如穿过套管针）植入心脏。